West nile virus causes: Difference between revisions
Jump to navigation
Jump to search
Joao Silva (talk | contribs) No edit summary |
Joao Silva (talk | contribs) |
||
| Line 8: | Line 8: | ||
==Biology== | ==Biology== | ||
<!-- | |||
West Nile virus is 1 of more than 70 viruses of the family Flaviviridae of the genus Flavivirus. Serologically, West Nile virus is a member of the Japanese encephalitis serocomplex, which includes Japanese en- cephalitis virus and an endemic North American flavivirus, St Louis encephalitis virus. West Nile viruses can be designated into at least 5 phylogenetic lineages.15 Only lineage 1 and 2 West Nile viruses have been associated with significant outbreaks in humans. | |||
Lineage 1 can be further subdivided into 3 sublineages: iso- lates from the western hemisphere, Africa, the Middle East, and Europe constitute lineage 1a; Kunjin virus from Australasia repre- sents lineage 1b; and lineage 1c consists of viruses from India.16 The initial North American isolates (East Coast genotype) identi- fied in 1999 in New York City have been most closely related to a lineage 1a West Nile virus isolated from Israel in 1998.17 Since approximately 2002, the East Coast genotype has largely been displaced by a new genotype (WN02 genotype) encompassing several conserved amino acid substitutions that may have increased the efficiency and rapidity of viral transmission in North American mosquito vectors.7,18 | |||
--> | |||
==Structure== | ==Structure== | ||
Revision as of 13:58, 11 September 2014
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Taxonomy
Viruses; ssRNA viruses; ssRNA positive-strand viruses, no DNA stage; Flaviviridae; Flavivirus; Japanese encephalitis virus group[1]
Biology
Structure
Tropism
Natural Reservoir
Natural reservoirs of the West Nile virus include:[2]
- Humans
- 65 different species of mosquitos
- 326 species of birds
References
- ↑ "West Nile Virus".
- ↑ Petersen LR, Brault AC, Nasci RS (2013). "West Nile virus: review of the literature". JAMA. 310 (3): 308–15. doi:10.1001/jama.2013.8042. PMID 23860989.