Enterovirus 68 historical perspective: Difference between revisions
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==Overview== | ==Overview== | ||
Human enterovirus 68 (EV-D68) was initially isolated in 1962 from samples of 4 hospitalized children presenting for [[pneumonia]] and [[bronchiolitis]] in California. It is a rare disease that has recently become more evident. The most recent outbreak occurred in USA on September 2014; it involved 10 states including Colorado, North Carolina, Georgia, Ohio, Iowa, Illinois, Missouri, Kansas, Oklahoma, and Kentucky. | Human enterovirus 68 (EV-D68) was initially isolated in 1962 from samples of 4 hospitalized children presenting for [[pneumonia]] and [[bronchiolitis]] in California. It is a rare disease that has recently become more clinically evident. The most recent outbreak occurred in USA on September 2014; it involved 10 states including Colorado, North Carolina, Georgia, Ohio, Iowa, Illinois, Missouri, Kansas, Oklahoma, and Kentucky. | ||
==Historical Perspective== | ==Historical Perspective== | ||
Revision as of 13:08, 12 September 2014
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
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Overview
Human enterovirus 68 (EV-D68) was initially isolated in 1962 from samples of 4 hospitalized children presenting for pneumonia and bronchiolitis in California. It is a rare disease that has recently become more clinically evident. The most recent outbreak occurred in USA on September 2014; it involved 10 states including Colorado, North Carolina, Georgia, Ohio, Iowa, Illinois, Missouri, Kansas, Oklahoma, and Kentucky.
Historical Perspective
Human enterovirus 68 (EV-D68) was initially isolated in 1962 from samples of 4 hospitalized children presenting for pneumonia and bronchiolitis in California.[1] While early descriptions of of EV-D68 identified the virus as acid resistant, newer reports refuted earlier findings and consistently confirmed the virus's acid sensitivity.[2][3][4] Prior to 2005, reports of EV-D68 infections were very limited. Only 26 cases of verified EV-D68 infection were documented between 1970 and 2005. EV-D68 is thus considered one of the rarest infectious enteroviruses, representing approximately 0.1% of all enterovirus isolates in that time frame. Over the past few years, outbreaks of EV-D68 have been documented in Japan, the Philippines, the Netherlands, and also in several clusters in the USA.[5] The most recent outbreak occurred in USA on late August and September 2014, with clusters reported in 10 states including Colorado, North Carolina, Georgia, Ohio, Iowa, Illinois, Missouri, Kansas, Oklahoma, and Kentucky.
References
- ↑ Schieble, JH.; Fox, VL.; Lennette, EH. (1967). "A probable new human picornavirus associated with respiratory diseases". Am J Epidemiol. 85 (2): 297–310. PMID 4960233. Unknown parameter
|month=ignored (help) - ↑ "A collaborative report: rhinoviruses--extension of the numbering system". Virology. 43 (2): 524–6. 1971. PMID 5543842.
- ↑ Savolainen C, Blomqvist S, Mulders MN, Hovi T (2002). "Genetic clustering of all 102 human rhinovirus prototype strains: serotype 87 is close to human enterovirus 70". J Gen Virol. 83 (Pt 2): 333–40. PMID 11807226.
- ↑ Ishiko H, Miura R, Shimada Y, Hayashi A, Nakajima H, Yamazaki S; et al. (2002). "Human rhinovirus 87 identified as human enterovirus 68 by VP4-based molecular diagnosis". Intervirology. 45 (3): 136–41. doi:65866 Check
|doi=value (help). PMID 12403917. - ↑ Tokarz R, Firth C, Madhi SA, Howie SR, Wu W, Sall AA; et al. (2012). "Worldwide emergence of multiple clades of enterovirus 68". J Gen Virol. 93 (Pt 9): 1952–8. doi:10.1099/vir.0.043935-0. PMC 3542132. PMID 22694903.