Cardiac allograft vasculopathy epidemiology and demographics: Difference between revisions
No edit summary |
No edit summary |
||
| Line 19: | Line 19: | ||
===Survival=== | ===Survival=== | ||
* Overall data from 1982 up to June 2011 shows 1 year survival of 81% and 5 year survival of 69%, with median survival of 11 years for all and 13 years for those surviving until the end of first year. The most recent cohort of patients show unadjusted 1 year survival of 84%. However, no significant change in survival was noted in the recent cohort at the end of first year. | * Overall data from 1982 up to June 2011 shows 1 year survival of 81% and 5 year survival of 69%, with median survival of 11 years for all and 13 years for those surviving until the end of first year. The most recent cohort of patients show unadjusted 1 year survival of 84%. However, no significant change in survival was noted in the recent cohort at the end of first year. | ||
* | |||
==References== | ==References== | ||
Revision as of 22:31, 12 September 2014
|
Cardiac allograft vasculopathy Microchapters |
|
Differentiating Cardiac allograft vasculopathy from other Diseases |
|---|
|
Diagnosis |
|
Treatment |
|
Case Studies |
|
Cardiac allograft vasculopathy epidemiology and demographics On the Web |
|
American Roentgen Ray Society Images of Cardiac allograft vasculopathy epidemiology and demographics |
|
FDA on Cardiac allograft vasculopathy epidemiology and demographics |
|
CDC on Cardiac allograft vasculopathy epidemiology and demographics |
|
Cardiac allograft vasculopathy epidemiology and demographics in the news |
|
Blogs on Cardiac allograft vasculopathy epidemiology and demographics |
|
Directions to Hospitals Treating Cardiac allograft vasculopathy |
|
Risk calculators and risk factors for Cardiac allograft vasculopathy epidemiology and demographics |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Aarti Narayan, M.B.B.S [2]; Raviteja Guddeti, M.B.B.S. [3]
Overview
As per data from the Registry of the International Society of Heart and Lung transplantation[1], the number of reported heart transplants has increased slowly in the recent years, especially in North America.
Epidemiology and Demographics
Donor demographics and characteristics
- In the recent cohort from the ISHLT (International Registry of Heart and Lung Transplant)[1], 69% of the donors are male and the incidence of female donor to male recipient transplantation is seen less frequently than previously.
- Average donor age is 34 years whereas average donor recipient age difference is 16 years.
- The leading cause of donor death was head trauma (46%) whereas the second most common cause was stroke (24%). Donor diabetes and hypertension is rare but increasing steadily. Average ischemia time was 3.3 hours (range 1.6 to 5.1 hours).
Recipient demographics and characteristics
- Cardiomyopathy and coronary artery disease are the most frequent diagnoses leading to a heart transplant. The proportion of recipients with history of cardiomyopathy is increasing over time.
- Increasing proportions of high risk patients like re-transplants, congenital heart diseases, co-morbidities like diabetes mellitus, hypertension, prior history of dialysis, previous malignancy and previous cardiac surgery reflect changes in patient characteristics over time. Also the use of left ventricular assist devices (LVAD's) in the interim period as a bridge to transplant has increased over time (28%).
- The average recipient age has stayed stable at 54 years in the last decade whereas the proportion of male recipients has decreased over years from 81% in 1992- 2000 to 76% in 2006- 2012.
Survival
- Overall data from 1982 up to June 2011 shows 1 year survival of 81% and 5 year survival of 69%, with median survival of 11 years for all and 13 years for those surviving until the end of first year. The most recent cohort of patients show unadjusted 1 year survival of 84%. However, no significant change in survival was noted in the recent cohort at the end of first year.
References
- ↑ 1.0 1.1 Taylor DO, Edwards LB, Boucek MM, Trulock EP, Aurora P, Christie J; et al. (2007). "Registry of the International Society for Heart and Lung Transplantation: twenty-fourth official adult heart transplant report--2007". J Heart Lung Transplant. 26 (8): 769–81. doi:10.1016/j.healun.2007.06.004. PMID 17692781.