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YazanDaaboul (talk | contribs)
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{{WBRQuestion
{{WBRQuestion
|QuestionAuthor={{Rim}}, {{AJL}} {{Alison}}
|QuestionAuthor={{YD}} (Reviewed by {{YD}})
|ExamType=USMLE Step 1
|ExamType=USMLE Step 1
|MainCategory=Biostatistics/Epidemiology
|MainCategory=Biostatistics/Epidemiology
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|MainCategory=Biostatistics/Epidemiology
|MainCategory=Biostatistics/Epidemiology
|SubCategory=Renal
|SubCategory=Renal
|MainCategory=Biostatistics/Epidemiology
|MainCategory=Biostatistics/Epidemiology
|MainCategory=Biostatistics/Epidemiology
|MainCategory=Biostatistics/Epidemiology
|MainCategory=Biostatistics/Epidemiology
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|MainCategory=Biostatistics/Epidemiology
|MainCategory=Biostatistics/Epidemiology
|SubCategory=Renal
|SubCategory=Renal
|Prompt=A case-control study investigating the association between the current use of non-steroidal anti-inflammatory drugs (NSAIDs), for more than 1 year, and impaired renal function. 2000 males and females over the age of 50 are surveyed and the results of the study have been categorized in the following table. Which of the following numbers represents the odds ratio for renal impairment among patients with a history of NSAID use, versus those without a history of NSAID use?
|Prompt=A case-control study is investigating the association between the chronic use of non-steroidal anti-inflammatory drugs (NSAIDs) over 1 year duration and impaired renal function. 2000 men and women over the age of 50 are surveyed, and the results of the study have been categorized in the following table. Which of the following numbers represents the odds ratio (OR) for renal impairment among patients with a history of chronic NSAID use, versus those without a history of chronic NSAID use?


[[Image:NSAID use WBR.png|300px]]
[[Image:NSAID use WBR.png|300px]]
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The odds ratio (OR) in this scenario is calculated using the equation:  
The odds ratio (OR) in this scenario is calculated using the equation:  
OR = ad/bc = (800 x 300)/(400 x 500) = 240000/200000 = 1.2
OR = ad/bc = (800 x 300)/(400 x 500) = 240000/200000 = 1.2
|EducationalObjectives= The odds ratio is calculated using the equation: OR = ad/bc
|References= First Aid 2014 page 50
|AnswerA=0.041
|AnswerA=0.041
|AnswerAExp=0.041 represents the attributable risk, calculated using the following equation:  
|AnswerAExp=0.041 represents the attributable risk, calculated using the following equation:  
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|AnswerBExp=0.500 does not correspond to any relevant value.
|AnswerBExp=0.500 does not correspond to any relevant value.
|AnswerC=1.066
|AnswerC=1.066
|AnswerCExp=1.066 represents the relative risk (RR), often used in cohort studies, calculated with the following equation:
|AnswerCExp=1.066 represents the relative risk (RR), often used in cohort studies. RR is calculated using the following equation:
RR = (a/[a+b]) / (c/[c+d])
RR = (a/[a+b]) / (c/[c+d])
|AnswerD=1.200
|AnswerD=1.200
|AnswerDExp=1.200 correctly corresponds to the odds ratio.
|AnswerDExp=1.200 correctly represents the OR
|AnswerE=1.500
|AnswerE=1.500
|AnswerEExp=1.500 does not correspond to any relevant value.
|AnswerEExp=1.500 does not represent any relevant value.
|EducationalObjectives=The odds ratio (OR) is calculated using the equation: OR = ad/bc
|References=First Aid 2014 page 50
|RightAnswer=D
|RightAnswer=D
|WBRKeyword= odds ratio, OR, formulas, formula, case-control, equation
|WBRKeyword=Odds ratio, OR, Case-control, Equation, NSAID, Renal impairment
|Approved=Yes
|Approved=Yes
}}
}}

Revision as of 01:20, 17 September 2014
Author [[PageAuthor::Yazan Daaboul, M.D. (Reviewed by Yazan Daaboul, M.D.)]]
Exam Type ExamType::USMLE Step 1
Main Category MainCategory::Biostatistics/Epidemiology
Sub Category SubCategory::Renal
Prompt [[Prompt::A case-control study is investigating the association between the chronic use of non-steroidal anti-inflammatory drugs (NSAIDs) over 1 year duration and impaired renal function. 2000 men and women over the age of 50 are surveyed, and the results of the study have been categorized in the following table. Which of the following numbers represents the odds ratio (OR) for renal impairment among patients with a history of chronic NSAID use, versus those without a history of chronic NSAID use?

]]

Answer A AnswerA::0.041
Answer A Explanation [[AnswerAExp::0.041 represents the attributable risk, calculated using the following equation:

Attributable Risk = (a/[a+b]) – (c/[c+d])]]

Answer B AnswerB::0.500
Answer B Explanation AnswerBExp::0.500 does not correspond to any relevant value.
Answer C AnswerC::1.066
Answer C Explanation [[AnswerCExp::1.066 represents the relative risk (RR), often used in cohort studies. RR is calculated using the following equation:

RR = (a/[a+b]) / (c/[c+d])]]

Answer D AnswerD::1.200
Answer D Explanation AnswerDExp::1.200 correctly represents the OR
Answer E AnswerE::1.500
Answer E Explanation AnswerEExp::1.500 does not represent any relevant value.
Right Answer RightAnswer::D
Explanation [[Explanation::

The odds ratio (OR) in this scenario is calculated using the equation: OR = ad/bc = (800 x 300)/(400 x 500) = 240000/200000 = 1.2
Educational Objective: The odds ratio (OR) is calculated using the equation: OR = ad/bc
References: First Aid 2014 page 50]]

Approved Approved::Yes
Keyword WBRKeyword::Odds ratio, WBRKeyword::OR, WBRKeyword::Case-control, WBRKeyword::Equation, WBRKeyword::NSAID, WBRKeyword::Renal impairment
Linked Question Linked::
Order in Linked Questions LinkedOrder::
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