JUPITER Trial: Difference between revisions
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Rim Halaby (talk | contribs) Created page with "__NOTOC__ {{LDL}} {{CMG}} '''Click here to download slides for JUPITER.''' ==Objective== ==References== {{Reflist|2}} {{Lipopedia}} Category:Lipopedia Catego..." |
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'''Click [[xxx|here]] to download slides for JUPITER.''' | '''Click [[xxx|here]] to download slides for JUPITER.''' | ||
== | ==Overview== | ||
This most recent trial randomly assigned 17,802 healthy subjects with LDL < 130 mg/dL and high-sensitivity CRP > 2 g/L to Rosuvastatin 20 mg daily or placebo. A significant reduction in the composite and individual components of the primary end-point of myocardial infarction, stroke, arterial revascularization hospitalization for unstable angina or death from cardiovascular causes and all-cause mortality was noted and trial was stopped earlier at 1.9 years (maximum of 5 years)<ref name="pmid18997196">{{cite journal| author=Ridker PM, Danielson E, Fonseca FA, Genest J, Gotto AM, Kastelein JJ et al.| title=Rosuvastatin to prevent vascular events in men and women with elevated C-reactive protein. | journal=N Engl J Med | year= 2008 | volume= 359 | issue= 21 | pages= 2195-207 | pmid=18997196 | doi=10.1056/NEJMoa0807646 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=18997196 }} [http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=19332604 Review in: Evid Based Med. 2009 Apr;14(2):48] [http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=19172709 Review in: Ann Intern Med. 2009 Jan 20;150(2):JC1-4] </ref>. | |||
==References== | ==References== | ||
Revision as of 04:16, 29 September 2014
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Low Density Lipoprotein Microchapters |
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Diagnosis |
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Treatment |
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Case Studies |
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JUPITER Trial On the Web |
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American Roentgen Ray Society Images of JUPITER Trial |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Click here to download slides for JUPITER.
Overview
This most recent trial randomly assigned 17,802 healthy subjects with LDL < 130 mg/dL and high-sensitivity CRP > 2 g/L to Rosuvastatin 20 mg daily or placebo. A significant reduction in the composite and individual components of the primary end-point of myocardial infarction, stroke, arterial revascularization hospitalization for unstable angina or death from cardiovascular causes and all-cause mortality was noted and trial was stopped earlier at 1.9 years (maximum of 5 years)[1].
References
- ↑ Ridker PM, Danielson E, Fonseca FA, Genest J, Gotto AM, Kastelein JJ; et al. (2008). "Rosuvastatin to prevent vascular events in men and women with elevated C-reactive protein". N Engl J Med. 359 (21): 2195–207. doi:10.1056/NEJMoa0807646. PMID 18997196. Review in: Evid Based Med. 2009 Apr;14(2):48 Review in: Ann Intern Med. 2009 Jan 20;150(2):JC1-4