HIV AIDS CT: Difference between revisions
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{{CMG}}; '''Associate Editors-in-Chief:''' [[User:Ujjwal Rastogi|Ujjwal Rastogi, MBBS]]; {{Ammu}} | {{CMG}}; '''Associate Editors-in-Chief:''' [[User:Ujjwal Rastogi|Ujjwal Rastogi, MBBS]]; {{Ammu}} | ||
==Overview== | ==Overview== | ||
CT scans of chest are important part of | CT scans of chest are an important part of the work-up of HIV patients presenting with [[pulmonary]] symptoms. CT scans may show similar findings observed on chest X-rays but carry the advantage of having greater sensitivity in the detection of early [[interstitial lung disease]], [[lymphadenopathy]], and pulmonary [[nodules]]. | ||
==CT== | ==CT== | ||
In HIV patients, nodules can result from bacterial infection ([[pneumonia]] or mycobacterial disease) or [[malignancy]] (most common being [[lymphoma]]). Nodules can be with or without cavitation. CT-guided transthoracic needle [[biopsy]] is used to make a definitive diagnosis. | In HIV patients, nodules can result from bacterial infection ([[pneumonia]] or mycobacterial disease) or [[malignancy]] (most common being [[lymphoma]]). Nodules can be with or without cavitation. CT-guided transthoracic needle [[biopsy]] is used to make a definitive diagnosis. |
Revision as of 16:11, 5 November 2014
AIDS Microchapters |
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [3]; Associate Editors-in-Chief: Ujjwal Rastogi, MBBS; Ammu Susheela, M.D. [4]
Overview
CT scans of chest are an important part of the work-up of HIV patients presenting with pulmonary symptoms. CT scans may show similar findings observed on chest X-rays but carry the advantage of having greater sensitivity in the detection of early interstitial lung disease, lymphadenopathy, and pulmonary nodules.
CT
In HIV patients, nodules can result from bacterial infection (pneumonia or mycobacterial disease) or malignancy (most common being lymphoma). Nodules can be with or without cavitation. CT-guided transthoracic needle biopsy is used to make a definitive diagnosis.
A prospective study done in 30 patients comparing the accuracy of high resolution CT in distinguishing between Pneumocystis carinii pneumonia and non- Pneumocystis carinii pneumonia in AIDS patients stated that the sensitivity, specificity, positive predictive and, negative predictive values of the HRCT for the diagnosis for PCP were 100, 83.3, 90.5 and 100 percent, respectively.[1]
HRCT fndings, that are suggestive of PCP are :
- Diffuse or ground glass pattern predominately in the upper lobes with or without cystic change.
HRCT fndings, that are not suggestive of PCP are :
- "Tree in bud" appearance.
- Consolidation.
- Bronchiectasis.
- Lymphadenopathy.
References
- ↑ Hidalgo A, Falcó V, Mauleón S, Andreu J, Crespo M, Ribera E, Pahissa A, Cáceres J (2003). "Accuracy of high-resolution CT in distinguishing between Pneumocystis carinii pneumonia and non- Pneumocystis carinii pneumonia in AIDS patients". Eur Radiol. 13 (5): 1179–84. doi:10.1007/s00330-002-1641-6. PMID 12695843. Retrieved 2012-02-12. Unknown parameter
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