Sleep-related hypoventilation

WikiDoc Resources for Sleep-related hypoventilation
Articles
Most recent articles on Sleep-related hypoventilation Most cited articles on Sleep-related hypoventilation Review articles on Sleep-related hypoventilation Articles on Sleep-related hypoventilation in N Eng J Med, Lancet, BMJ
Media
Powerpoint slides on Sleep-related hypoventilation Images of Sleep-related hypoventilation Photos of Sleep-related hypoventilation Podcasts & MP3s on Sleep-related hypoventilation Videos on Sleep-related hypoventilation
Evidence Based Medicine
Cochrane Collaboration on Sleep-related hypoventilation Bandolier on Sleep-related hypoventilation TRIP on Sleep-related hypoventilation
Clinical Trials
Ongoing Trials on Sleep-related hypoventilation at Clinical Trials.gov Trial results on Sleep-related hypoventilation Clinical Trials on Sleep-related hypoventilation at Google
Guidelines / Policies / Govt
US National Guidelines Clearinghouse on Sleep-related hypoventilation NICE Guidance on Sleep-related hypoventilation NHS PRODIGY Guidance FDA on Sleep-related hypoventilation CDC on Sleep-related hypoventilation
Books
Books on Sleep-related hypoventilation
News
Sleep-related hypoventilation in the news Be alerted to news on Sleep-related hypoventilation News trends on Sleep-related hypoventilation
Commentary
Blogs on Sleep-related hypoventilation
Definitions
Definitions of Sleep-related hypoventilation
Patient Resources / Community
Patient resources on Sleep-related hypoventilation Discussion groups on Sleep-related hypoventilation Patient Handouts on Sleep-related hypoventilation Directions to Hospitals Treating Sleep-related hypoventilation Risk calculators and risk factors for Sleep-related hypoventilation
Healthcare Provider Resources
Symptoms of Sleep-related hypoventilation Causes & Risk Factors for Sleep-related hypoventilation Diagnostic studies for Sleep-related hypoventilation Treatment of Sleep-related hypoventilation
Continuing Medical Education (CME)
CME Programs on Sleep-related hypoventilation
International
Sleep-related hypoventilation en Espanol Sleep-related hypoventilation en Francais
Business
Sleep-related hypoventilation in the Marketplace Patents on Sleep-related hypoventilation
Experimental / Informatics
List of terms related to Sleep-related hypoventilation

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Jesus Rosario Hernandez, M.D. [2]

Differential Diagnosis

• Lung diseases
• Skeletal malformations
• Neuromuscular disorders
• Sleep-related hypoxemia
• Obstructive sleep apnea hypopnea
• Central sleep apnea

Epidemiology and Demographics

Prevalence

The prevalence of sleep-related hypoventilation is unknown of the overall population.

Risk Factors

• Central nervous system depressants intake (e.g. benzodiazepines, opioid, alcohol)
• Hypothiroidism
• Neuromuscular or chest wall disorder
• Pulmonary disorder

Natural History, Complications and Prognosis

Prognosis

Poor prognostic criteria include:

• Central nervous system depressants intake (e.g. benzodiazepines, opioid, alcohol)
• Hypothiroidism
• Neuromuscular or chest wall disorder

• Amyotrophic lateral sclerosis
• Spinal cord injury
• Diaphragmatic paralysis
• Myasthenia gravis
• Lambert-Eaton syndrome
• Toxic or metabolic myopathies
• Postpolio syndrome
• Char-cot-Marie-Tooth syndrome

• Pulmonary disorder

Diagnostic Criteria

DSM-V Diagnostic Criteria for Paranoid Personality Disorder

“

A. Polysomnograpy demonstrates episodes of decreased respiration associated with elevated CO2 levels. (Note: In the absence of objective measurement of CO2, persistent low levels of hemoglobin oxygen saturation unassociated with apneic/hypopneic events may indicate hypoventilation.) B. The disturbance is not better explained by another current sleep disorder. Specify whether: Idiopathic hiypoventilation: This subtype is not attributable to any readily identified condition. Congenital central alveolar hypoventilation: This subtype is a rare congenital disorder in which the individual typically presents in the perinatal period with shallow breathing, or cyanosis and apnea during sleep. Comorbid sleep-related hypoventilation: This subtype occurs as a consequence of a medical condition, such as a pulmonary disorder (e.g., interstitial lung disease, chronic obstructive pulmonary disease) or a neuromuscular or chest wall disorder (e.g., muscular dystrophies, postpolio syndrome, cervical spinal cord injury, kyphoscoliosis), or medications (e.g., benzodiazepines, opiates). It also occurs with obesity (obesity hypoventilation disorder), where it reflects a combination of increased work of breathing due to reduced chest wall compliance and ventilation-perfusion mismatch and variably reduced ventilatory drive. Such individuals usually are characterized by body mass index of greater than 30 and hypercapnia during wakefulness (with a PCO2 of greater than 45), without other evidence of hypoventilation. Specify current severity: Severity is graded according to the degree of hypoxemia and hypercarbia present during sleep and evidence of end organ impairment due to these abnormalities (e.g., right sided heart failure). The presence of blood gas abnormalities during wakefulness is an indicator of greater severity.

”