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*The causative agent was described as intracellular oval cocci in a cerebrospinal fluid sample by Marchiafava and Celli in 1884.
*The causative agent was described as intracellular oval cocci in a cerebrospinal fluid sample by Marchiafava and Celli in 1884.
*The organism was isolated by Anton Weischselbaum in 1887 and he gave the term Diplococcus intracellularis meningitidis.
*The organism was isolated by Anton Weischselbaum in 1887 and he gave the term Diplococcus intracellularis meningitidis.
*From then on for more than 2 hundred years, meningococcus have been caused high rates of morbidity and mortality all around the world.
*From then on for more than 2 hundred years, meningococcus has caused high rates of morbidity and mortality all around the world.
*No reports of outbreaks have been reported prior to 1806.
*The first meningococcal epidemics occured in early 1900s in sub saharan Africa.
 





Revision as of 17:57, 14 November 2014

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] ; Associate Editor(s)-in-Chief: Ammu Susheela, M.D. [2]

Overview

Historical Perspective

  • Records indicate that the first case of meningococcal meningitis was described in Geneva in 1805.[1]
  • Another case was reported in New England , New Bedford , Massachusetts in 1806.[2]
  • The causative agent was described as intracellular oval cocci in a cerebrospinal fluid sample by Marchiafava and Celli in 1884.
  • The organism was isolated by Anton Weischselbaum in 1887 and he gave the term Diplococcus intracellularis meningitidis.
  • From then on for more than 2 hundred years, meningococcus has caused high rates of morbidity and mortality all around the world.
  • No reports of outbreaks have been reported prior to 1806.
  • The first meningococcal epidemics occured in early 1900s in sub saharan Africa.


References

  1. "Meningococcus".
  2. Stephens DS (2009). "Biology and pathogenesis of the evolutionarily successful, obligate human bacterium Neisseria meningitidis". Vaccine. 27 Suppl 2: B71–7. doi:10.1016/j.vaccine.2009.04.070. PMC 2712446. PMID 19477055.