'''Beclometasone dipropionate''' ([[International Nonproprietary Name|INN]] modified) or '''beclomethasone dipropionate''' ([[United States Adopted Name|USAN]], former [[British Approved Name|BAN]]), also referred to as '''beclometasone''' (INN), is a potent Class A [[glucocorticoid]] [[steroid]] drug. In the form of an [[inhaler]] (e.g. Becotide), a wide number of brands of which are available, it is used for the prophylaxis of [[asthma]]. As a [[nasal spray]] (e.g. Beconase, Vancenase), it is used for the treatment of [[rhinitis]] (e.g. [[hayfever]]) and [[sinusitis]]. In some instances it is used by oral pathologists in the treatment of unusually severe canker sores.
As a cream or ointment (trade name Propaderm) it is used to treat severe inflammatory skin disorders (e.g. [[eczema]]) unresponsive to less potent steroids, but is generally avoided in the treatment of [[psoriasis]] due to the risk of rebound on withdrawal.
==Chemistry==
It is a white to creamy-white, odorless powder which is very slightly soluble in [[water]], very soluble in [[chloroform]], and freely soluble in [[acetone]] and in [[ethanol]].
==Side effects==
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Occasionally it may cause a [[cough]] upon inhalation. Deposition on the [[tongue]] and [[throat]] may promote oral [[candidiasis]] which appears as a white coating, possibly with irritation.<!--
--><ref>{{cite journal | author=Salzman G, Pyszczynski D | title=Oropharyngeal candidiasis in patients treated with beclomethasone dipropionate delivered by metered-dose inhaler alone and with Aerochamber. | journal=J Allergy Clin Immunol | volume=81 | issue=2 | pages=424-8 | year=1988 | id=PMID 3339197}}</ref><!--
--><ref>{{cite journal | author=Fukushima C, Matsuse H, Tomari S, Obase Y, Miyazaki Y, Shimoda T, Kohno S | title=Oral candidiasis associated with inhaled corticosteroid use: comparison of fluticasone and beclomethasone. | journal=Ann Allergy Asthma Immunol | volume=90 | issue=6 | pages=646-51 | year=2003 | id=PMID 12839324}}</ref>
This may usually be prevented by rinsing the mouth with water after using the inhaler. Other [[adverse drug reaction|side effect]]s may rarely include unpleasant taste, [[hoarseness]] or [[nasal congestion]], pain or headache and visual changes. [[Allergic reaction]]s rarely may occur.
As a steroid, it can also cause occurrences of retina detachments, by triggering Central Serous Retinopathy.
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Black Box Warning
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See full prescribing information for complete Boxed Warning.
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Overview
Beclomethasone dipropionate (inhalation) is a corticosteroid that is FDA approved for the {{{indicationType}}} of . There is a Black Box Warning for this drug as shown here. Common adverse reactions include .
Adult Indications and Dosage
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Off-Label Use and Dosage (Adult)
Guideline-Supported Use
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There is limited information regarding Off-Label Guideline-Supported Use of Beclomethasone dipropionate (inhalation) in adult patients.
Non–Guideline-Supported Use
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There is limited information regarding Off-Label Non–Guideline-Supported Use of Beclomethasone dipropionate (inhalation) in adult patients.
Pediatric Indications and Dosage
FDA-Labeled Indications and Dosage (Pediatric)
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There is limited information regarding FDA-Labeled Use of Beclomethasone dipropionate (inhalation) in pediatric patients.
Off-Label Use and Dosage (Pediatric)
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There is limited information regarding Off-Label Guideline-Supported Use of Beclomethasone dipropionate (inhalation) in pediatric patients.
Non–Guideline-Supported Use
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There is limited information regarding Off-Label Non–Guideline-Supported Use of Beclomethasone dipropionate (inhalation) in pediatric patients.
Contraindications
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Warnings
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Clinical Trials Experience
There is limited information regarding Clinical Trial Experience of Beclomethasone dipropionate (inhalation) in the drug label.
Body as a Whole
Cardiovascular
Digestive
Endocrine
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Metabolic and Nutritional
Musculoskeletal
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Postmarketing Experience
There is limited information regarding Postmarketing Experience of Beclomethasone dipropionate (inhalation) in the drug label.
There is limited information regarding Patient Counseling Information of Beclomethasone dipropionate (inhalation) in the drug label.
Precautions with Alcohol
Alcohol-Beclomethasone dipropionate (inhalation) interaction has not been established. Talk to your doctor about the effects of taking alcohol with this medication.