|fdaLIADAdult=temporarily relieves these symptoms due to hay fever or other upper respiratory allergies:
|fdaLIADAdult=* Temporarily relieves these symptoms due to hay fever or other upper respiratory allergies:
runny nose
:* Runny nose
sneezing
:* Sneezing
itchy, watery eyes
:* Itchy, watery eyes
itchy nose or throat
:* Itchy nose or throat
temporarily relieves these symptoms of the common cold:
runny nose
sneezing
take every 4 to 6 hours, not more than 6 doses in 24 hours
|offLabelAdultGuideSupport======Condition1=====
* Developed by:
* Class of Recommendation:
* Strength of Evidence:
* Dosing Information
:* Dosage
=====Condition2=====
* Temporarily relieves these symptoms of the common cold:
:* Runny nose
There is limited information regarding <i>Off-Label Guideline-Supported Use</i> of {{PAGENAME}} in adult patients.
:* Sneezing
<!--Non–Guideline-Supported Use (Adult)-->
|offLabelAdultNoGuideSupport======Condition1=====
* Dosing Information
* Dosing Information
:* Dosage
:* Take every 4 to 6 hours, not more than 6 doses in 24 hours
|offLabelAdultGuideSupport=* Chemotherapy-induced nausea and vomiting.
=====Condition2=====
* Extrapyramidal disease - Medication-induced movement disorder.
* Hyperemesis gravidarum.
There is limited information regarding <i>Off-Label Non–Guideline-Supported Use</i> of {{PAGENAME}} in adult patients.
* Local anesthesia
|offLabelAdultNoGuideSupport=There is limited information regarding <i>Off-Label Non–Guideline-Supported Use</i> of Diphenhydramine in adult patients.
<!--Pediatric Indications and Dosage-->
<!--Pediatric Indications and Dosage-->
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<!--Guideline-Supported Use (Pediatric)-->
<!--Guideline-Supported Use (Pediatric)-->
|offLabelPedGuideSupport======Condition1=====
|offLabelPedGuideSupport=There is limited information regarding <i>Off-Label Guideline-Supported Use</i> of Diphenhydramine in pediatric patients.
* Developed by:
* Class of Recommendation:
* Strength of Evidence:
* Dosing Information
:* Dosage
=====Condition2=====
There is limited information regarding <i>Off-Label Guideline-Supported Use</i> of {{PAGENAME}} in pediatric patients.
<!--Non–Guideline-Supported Use (Pediatric)-->
<!--Non–Guideline-Supported Use (Pediatric)-->
|offLabelPedNoGuideSupport======Condition1=====
|offLabelPedNoGuideSupport=There is limited information regarding <i>Off-Label Non–Guideline-Supported Use</i> of Diphenhydramine in pediatric patients.
* Dosing Information
<!--Contraindications-->
|contraindications=* Diphenhydramine is contraindicated in persons with known hypersensitivity.
:* Dosage
=====Condition2=====
There is limited information regarding <i>Off-Label Non–Guideline-Supported Use</i> of {{PAGENAME}} in pediatric patients.
<!--Contraindications-->
|contraindications=* Condition1
<!--Warnings-->
|warnings=* Do not use with any other product containing diphenhydramine, even one used on skin
|warnings=Do not use
* To make a child sleepy
with any other product containing diphenhydramine, even one used on skin
* Ask a doctor before use if you have glaucoma
to make a child sleepy
* Trouble urinating due to an enlarged prostate gland
Ask a doctor before use if you have
* A breathing problem such as emphysema or chronic bronchitis
glaucoma
* Ask a doctor or pharmacist before use if you are taking sedatives or tranquilizers
trouble urinating due to an enlarged prostate gland
a breathing problem such as emphysema or chronic bronchitis
Ask a doctor or pharmacist before use if you are
taking sedatives or tranquilizers
When using this product
When using this product
Line 119:
Line 80:
Keep out of reach of children.
Keep out of reach of children.
In case of overdose, get medical help or contact a Poison Control Center right away.
In case of overdose, get medical help or contact a Poison Control Center right away.
|clinicalTrials=There is limited information regarding <i>Clinical Trial Experience</i> of {{PAGENAME}} in the drug label.
|clinicalTrials======Digestive=====
* Xerostomia
=====Body as a Whole=====
=====Cardiovascular=====
=====Digestive=====
=====Endocrine=====
=====Hematologic and Lymphatic=====
=====Metabolic and Nutritional=====
=====Musculoskeletal=====
=====Neurologic=====
=====Neurologic=====
* Sedation
* Dizziness
* Dyskinesia
* Somnolence
=====Respiratory=====
=====Respiratory=====
* Dryness of nasal mucosa
* Pharyngeal dryness
* Thick sputum
* Bronchial dryness
=====Miscellaneous====
* Anaphylaxis reaction
=====Skin and Hypersensitivy Reactions=====
=====Special Senses=====
=====Urogenital=====
=====Miscellaneous=====
<!--Postmarketing Experience-->
<!--Postmarketing Experience-->
|postmarketing=There is limited information regarding <i>Postmarketing Experience</i> of {{PAGENAME}} in the drug label.
|postmarketing=There is limited information regarding <i>Postmarketing Experience</i> of Diphenhydramine in the drug label.
=====Body as a Whole=====
=====Body as a Whole=====
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<!--Drug Interactions-->
<!--Drug Interactions-->
|drugInteractions=* Drug
|drugInteractions=There is limited information regarding <i>drug interactions</i> of Diphenhydramine in the drug label.
:* Description
|FDAPregCat=B
<!--Use in Specific Populations-->
|useInPregnancyFDA=* '''Pregnancy Category'''
|useInPregnancyFDA=* '''Pregnancy Category'''
|useInPregnancyAUS=* '''Australian Drug Evaluation Committee (ADEC) Pregnancy Category'''
|useInPregnancyAUS=* '''Australian Drug Evaluation Committee (ADEC) Pregnancy Category'''
There is no Australian Drug Evaluation Committee (ADEC) guidance on usage of {{PAGENAME}} in women who are pregnant.
There is no Australian Drug Evaluation Committee (ADEC) guidance on usage of Diphenhydramine in women who are pregnant.
|useInLaborDelivery=There is no FDA guidance on use of {{PAGENAME}} during labor and delivery.
|useInLaborDelivery=There is no FDA guidance on use of Diphenhydramine during labor and delivery.
|useInNursing=There is no FDA guidance on the use of {{PAGENAME}} with respect to nursing mothers.
|useInNursing=There is no FDA guidance on the use of Diphenhydramine with respect to nursing mothers.
|useInPed=There is no FDA guidance on the use of {{PAGENAME}} with respect to pediatric patients.
|useInPed=* Keep out of reach of children.
|useInGeri=There is no FDA guidance on the use of {{PAGENAME}} with respect to geriatric patients.
* In case of overdose, get medical help or contact a Poison Control Center right away.
|useInGender=There is no FDA guidance on the use of {{PAGENAME}} with respect to specific gender populations.
|useInGeri=There is no FDA guidance on the use of Diphenhydramine with respect to geriatric patients.
|useInRace=There is no FDA guidance on the use of {{PAGENAME}} with respect to specific racial populations.
|useInGender=There is no FDA guidance on the use of Diphenhydramine with respect to specific gender populations.
|useInRenalImpair=There is no FDA guidance on the use of {{PAGENAME}} in patients with renal impairment.
|useInRace=There is no FDA guidance on the use of Diphenhydramine with respect to specific racial populations.
|useInHepaticImpair=There is no FDA guidance on the use of {{PAGENAME}} in patients with hepatic impairment.
|useInRenalImpair=There is no FDA guidance on the use of Diphenhydramine in patients with renal impairment.
|useInReproPotential=There is no FDA guidance on the use of {{PAGENAME}} in women of reproductive potentials and males.
|useInHepaticImpair=There is no FDA guidance on the use of Diphenhydramine in patients with hepatic impairment.
|useInImmunocomp=There is no FDA guidance one the use of {{PAGENAME}} in patients who are immunocompromised.
|useInReproPotential=There is no FDA guidance on the use of Diphenhydramine in women of reproductive potentials and males.
|useInImmunocomp=There is no FDA guidance one the use of Diphenhydramine in patients who are immunocompromised.
<!--Administration and Monitoring-->
<!--Administration and Monitoring-->
|administration=* Oral
|administration=* Intramuscular
* Intravenous
* Intravenous
|monitoring=There is limited information regarding <i>Monitoring</i> of {{PAGENAME}} in the drug label.
* Oral
|monitoring=There is limited information regarding <i>Monitoring</i> of Diphenhydramine in the drug label.
* Description
<!--IV Compatibility-->
<!--IV Compatibility-->
|IVCompat=There is limited information regarding <i>IV Compatibility</i> of {{PAGENAME}} in the drug label.
|IVCompat=There is limited information regarding <i>IV Compatibility</i> of Diphenhydramine in the drug label.
<!--Overdosage-->
<!--Overdosage-->
|overdose====Acute Overdose===
|overdose=There is limited information regarding <i>Chronic Overdose</i> of Diphenhydramine in the drug label.
====Signs and Symptoms====
* Description
====Management====
* Description
===Chronic Overdose===
There is limited information regarding <i>Chronic Overdose</i> of {{PAGENAME}} in the drug label.
<!--Pharmacology-->
<!--Pharmacology-->
Line 304:
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<!--Nonclinical Toxicology-->
<!--Nonclinical Toxicology-->
|nonClinToxic=There is limited information regarding <i>Nonclinical Toxicology</i> of {{PAGENAME}} in the drug label.
|nonClinToxic=There is limited information regarding <i>Nonclinical Toxicology</i> of Diphenhydramine in the drug label.
<!--Clinical Studies-->
<!--Clinical Studies-->
|clinicalStudies=There is limited information regarding <i>Clinical Studies</i> of {{PAGENAME}} in the drug label.
|clinicalStudies=There is limited information regarding <i>Clinical Studies</i> of Diphenhydramine in the drug label.
<!--How Supplied-->
<!--How Supplied-->
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<!--Patient Counseling Information-->
<!--Patient Counseling Information-->
|storage=store at 20°-25°C
|storage=store at 20°-25°C
|fdaPatientInfo=* Marked drowsiness may occur
* Avoid alcoholic drinks
* Excitability may occur, especially in children
* Alcohol, sedatives and tranquilizers may increase drowsiness
* Be careful when driving a motor vehicle or operating machinery
|alcohol=* Avoid alcoholic drinks.
|fdaPatientInfo=marked drowsiness may occur
* Alcohol, sedatives and tranquilizers may increase drowsiness.
avoid alcoholic drinks
|brandNames=* Benadryl®
excitability may occur, especially in children
* Benylin Decongestant Cough®
alcohol, sedatives and tranquilizers may increase drowsiness
* Diphenhist
be careful when driving a motor vehicle or operating machinery
* Diphenyl®
|alcohol=avoid alcoholic drinks
* Genahist®
* Geridryl®
alcohol, sedatives and tranquilizers may increase drowsiness
* Nytol Quickcaps®
* Nytol Quickgels®
|brandNames=* ®<ref>{{Cite web | title = | url = }}</ref>
|lookAlike=* Benadryl® - benazepril®
* diphenhydrAMINE® - dimenhyDRINATE®
<!--Look-Alike Drug Names-->
|lookAlike=* A® — B®<ref name="www.ismp.org">{{Cite web | last = | first = | title = http://www.ismp.org | url = http://www.ismp.org | publisher = | date = }}</ref>
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Overview
Diphenhydramine is a Analgesic , Antihistamine that is FDA approved for the treatment of temporarily relieves symptoms of the common cold like
runny nose, sneezing, itchy watery eyes, itchy nose or throat. Common adverse reactions include Xerostomia, dizziness, dyskinesia, sedatation, somnolence
dryness of nasal mucosa, pharyngeal dryness, thick sputum..
Adult Indications and Dosage
FDA-Labeled Indications and Dosage (Adult)
Temporarily relieves these symptoms due to hay fever or other upper respiratory allergies:
Runny nose
Sneezing
Itchy, watery eyes
Itchy nose or throat
Temporarily relieves these symptoms of the common cold:
Runny nose
Sneezing
Dosing Information
Take every 4 to 6 hours, not more than 6 doses in 24 hours
Off-Label Use and Dosage (Adult)
Guideline-Supported Use
Chemotherapy-induced nausea and vomiting.
Extrapyramidal disease - Medication-induced movement disorder.
Hyperemesis gravidarum.
Local anesthesia
Non–Guideline-Supported Use
There is limited information regarding Off-Label Non–Guideline-Supported Use of Diphenhydramine in adult patients.
Pediatric Indications and Dosage
FDA-Labeled Indications and Dosage (Pediatric)
Condition1
Dosing Information
Dosage
Condition2
There is limited information regarding FDA-Labeled Use of Diphenhydramine in pediatric patients.
Off-Label Use and Dosage (Pediatric)
Guideline-Supported Use
There is limited information regarding Off-Label Guideline-Supported Use of Diphenhydramine in pediatric patients.
Non–Guideline-Supported Use
There is limited information regarding Off-Label Non–Guideline-Supported Use of Diphenhydramine in pediatric patients.
Contraindications
Diphenhydramine is contraindicated in persons with known hypersensitivity.
Warnings
Do not use with any other product containing diphenhydramine, even one used on skin
To make a child sleepy
Ask a doctor before use if you have glaucoma
Trouble urinating due to an enlarged prostate gland
A breathing problem such as emphysema or chronic bronchitis
Ask a doctor or pharmacist before use if you are taking sedatives or tranquilizers
When using this product
marked drowsiness may occur
avoid alcoholic drinks
excitability may occur, especially in children
alcohol, sedatives and tranquilizers may increase drowsiness
be careful when driving a motor vehicle or operating machinery
If pregnant or breast-feeding,
ask a health professional before use.
Keep out of reach of children.
In case of overdose, get medical help or contact a Poison Control Center right away.
Adverse Reactions
Clinical Trials Experience
Digestive
Xerostomia
Neurologic
Sedation
Dizziness
Dyskinesia
Somnolence
Respiratory
Dryness of nasal mucosa
Pharyngeal dryness
Thick sputum
Bronchial dryness
=Miscellaneous
Anaphylaxis reaction
Postmarketing Experience
There is limited information regarding Postmarketing Experience of Diphenhydramine in the drug label.
Body as a Whole
Cardiovascular
Digestive
Endocrine
Hematologic and Lymphatic
Metabolic and Nutritional
Musculoskeletal
Neurologic
Respiratory
Skin and Hypersensitivy Reactions
Special Senses
Urogenital
Miscellaneous
Drug Interactions
There is limited information regarding drug interactions of Diphenhydramine in the drug label.