Respiratory failure causes

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

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Causes

Common Causes

• Codeine
• Clozapine
• Fentanyl
• Gamma-Hydroxybutyric acid
• Heroin
• Ketamine
• Lidocaine
• Labetalol
• Lorazepam
• Morphine
• Nitrazepam
• Opiate
• Oxymorphone
• Procainamide (patient information)
• Sodium thiopental
• Triazolam
• Zopiclone

Causes by Organ System

Cardiovascular	Atrial septal defect (ostium primum), Ebstein anomaly, Eisenmenger syndrome, Fallot tetralogy, Pulmonary valve stenosis, Transposition of great arteries, Tricuspid valve stenosis, Ventricular septal defect -
Chemical / poisoning	3-Quinuclidinyl benzilate, Abrin, Aldicarb, Alpha-amanitin, Barium nitrate, Bungarotoxin, Carbon monoxide poisoning, Cocaine, Cone snail, Cyclophosphamide, Furfural, Snakebites (Patient information)
Congenital	Atrial septal defect (ostium primum), Bland-White-Garland Syndrome, Congenital Central Hypoventilation Syndrome, Congenital diaphragmatic hernia, Fallot tetralogy, Fetal circulation, persistent, Respiratory distress syndrome (neonatal)
Dermatologic	No underlying causes
Drug Side Effect	Codeine, Clozapine, Fentanyl, Gamma-Hydroxybutyric acid, Heroin, Ketamine, Lidocaine, Labetalol, Lorazepam, Morphine, Nitrazepam, Opiate, Oxymorphone, Pramipexole, Procainamide (patient information), Sodium thiopental, Tretinoin, Triazolam, Zopiclone
Ear Nose Throat	No underlying causes
Endocrine	No underlying causes
Environmental	Asbestosis, Coal worker pneumoconiosis, Smoke inhalation, Sulfur dioxide
Gastroenterologic	Hepatic failure, Hepatopulmonary syndrome
Genetic	Achondrogenesis, Acute Porphyria, Alpha 1-antitrypsin deficiency, Atelosteogenesis, type II, Becker's muscular dystrophy, Carnitine palmitoyltransferase II deficiency, Cystic fibrosis, Duchenne's Muscular Dystrophy, Familial dysautonomia, Hereditary haemorrhagic telangiectasia, Osteogenesis imperfecta, Thanatophoric dysplasia
Hematologic	Acute Porphyria, Cholesterol Emboli Syndrome, Fat embolism, Sepsis
Iatrogenic	Blood transfusion, EVAR
Infectious Disease	Babesiosis, Botulism, Crimean-Congo hemorrhagic fever, Hantavirus Pulmonary Syndrome, Heartworm, Post-polio syndrome, Rabies, Tetanus
Musculoskeletal / Ortho	Kyphoscoliosis
Neurologic	Amyotrophic Lateral Sclerosis, Meningitis, Polyrediculitis, Zellweger syndrome
Nutritional / Metabolic	Metabolic Acidosis
Obstetric/Gynecologic	No underlying causes
Oncologic	Malignant Mesothelioma
Ophthalmologic	No underlying causes
Overdose / Toxicity	Acetylsalicylic acid, Alcohol, Bufotenin, Clitocybe dealbata, Colchicine, Cytisine, Dicofol, Saxitoxin, Tetrodotoxin, Tick paralysis, Vinyl chloride
Psychiatric	No underlying causes
Pulmonary	Acute lung syndrome, Acute Respiratory Distress Syndrome, Alpha 1-antitrypsin deficiency, Atelectasis, Bronchial asthma, Bronchiectasis, Bronchiolitis, Bronchiolitis obliterans, Bronchogenic carcinoma, Bronchopulmonary dysplasia, Chronic Obstructive Pulmonary Disease, Cystic adenomatoid malformation of lung, Emphysema, Eosinophilic pneumonia, Fibrosing alveolitis, Flail chest, Interstitial fibrosis, Laryngo-/Bronchospasm, Legionella pneumophila, Pleural effusion, Pneumonia, Pneumothorax, Pulmonary alveolar proteinosis, Pulmonary arterio-venous malformation, Pulmonary edema, Pulmonary embolism, Pulmonary hypertension, Pulmonary oedema, Restrictive Lung Disease, Status asthmaticus
Renal / Electrolyte	Electrolyte abnormalities
Rheum / Immune / Allergy	Acute motor axonal neuropathy, Anaphylaxis, Angioedema, Antiphospholipid Antibody Syndrome, Devic's disease, Guillain-Barre syndrome, Hamman-Rich Syndrome, Myasthenia Gravis, Satoyoshi syndrome
Trauma	Ebstein anomaly, Flail chest
Urologic	No underlying causes
Miscellaneous	Aspiration, Foreign body, Malignant hyperpyrexia, Multiple organ dysfunction syndrome, Near-drowning, Reye's syndrome