Budd-Chiari syndrome causes: Difference between revisions
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Revision as of 14:58, 28 January 2015
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Budd-Chiari syndrome Microchapters |
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Diagnosis |
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Treatment |
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Budd-Chiari syndrome causes On the Web |
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American Roentgen Ray Society Images of Budd-Chiari syndrome causes |
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Risk calculators and risk factors for Budd-Chiari syndrome causes |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Causes
- Primary (75%): thrombosis of the hepatic vein
- Secondary (25%): compression of the hepatic vein by an outside structure (e.g. a tumor)
Often, the patient is known to have a tendency towards thrombosis, although Budd-Chiari syndrome can also be the first symptom of such a tendency. Genetic causes
- Protein C deficiency
- Protein S deficiency
- Factor V Leiden mutation
Other causes
A related condition is veno-occlusive disease, which occurs in recipients of bone marrow transplants as a complication of their medication. Although its mechanism is similar, it is not considered a form of Budd-Chiari syndrome.
References
- ↑ Patel RK, Lea NC, Heneghan MA, Westwood NB, Milojkovic D, Thanigaikumar M, Yallop D, Arya R, Pagliuca A, Gaken J, Wendon J, Heaton ND, Mufti GJ. Prevalence of the activating JAK2 tyrosine kinase mutation V617F in the Budd-Chiari syndrome. Gastroenterology. 2006 Jun;130(7):2031-8.