Isopropyl alcohol: Difference between revisions
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{{DrugProjectFormSinglePage | {{DrugProjectFormSinglePage | ||
|authorTag= | |authorTag={{Ammu}} | ||
|genericName=topical antimicrobial | |||
|aOrAn=a | |aOrAn=a | ||
| | |drugClass=antiseptic | ||
|adverseReactions= | |indicationType=treatment | ||
|indication=cuts, scrapes and minor muscular aches | |||
|adverseReactions=hypersensitivity | |||
|blackBoxWarningTitle=<span style="color:#FF0000;">ConditionName: </span> | |blackBoxWarningTitle=<span style="color:#FF0000;">ConditionName: </span> | ||
|blackBoxWarningBody=<i><span style="color:#FF0000;">ConditionName: </span></i> | |blackBoxWarningBody=<i><span style="color:#FF0000;">ConditionName: </span></i> | ||
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<!--FDA-Labeled Indications and Dosage (Adult)--> | <!--FDA-Labeled Indications and Dosage (Adult)--> | ||
|fdaLIADAdult= | |fdaLIADAdult=to decrease germs in minor cuts and scrapes. | ||
helps relieve minor muscular aches due to exertion. | |||
|offLabelAdultGuideSupport= | |||
There is limited information regarding <i>Off-Label Guideline-Supported Use</i> of {{PAGENAME}} in adult patients. | There is limited information regarding <i>Off-Label Guideline-Supported Use</i> of {{PAGENAME}} in adult patients. | ||
<!--Non–Guideline-Supported Use (Adult)--> | <!--Non–Guideline-Supported Use (Adult)--> | ||
|offLabelAdultNoGuideSupport | |offLabelAdultNoGuideSupport= | ||
There is limited information regarding <i>Off-Label Non–Guideline-Supported Use</i> of {{PAGENAME}} in adult patients. | There is limited information regarding <i>Off-Label Non–Guideline-Supported Use</i> of {{PAGENAME}} in adult patients. | ||
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<!--FDA-Labeled Indications and Dosage (Pediatric)--> | <!--FDA-Labeled Indications and Dosage (Pediatric)--> | ||
|fdaLIADPed | |fdaLIADPed= | ||
There is limited information regarding <i>FDA-Labeled Use</i> of {{PAGENAME}} in pediatric patients. | There is limited information regarding <i>FDA-Labeled Use</i> of {{PAGENAME}} in pediatric patients. | ||
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<!--Guideline-Supported Use (Pediatric)--> | <!--Guideline-Supported Use (Pediatric)--> | ||
|offLabelPedGuideSupport= | |offLabelPedGuideSupport= | ||
There is limited information regarding <i>Off-Label Guideline-Supported Use</i> of {{PAGENAME}} in pediatric patients. | There is limited information regarding <i>Off-Label Guideline-Supported Use</i> of {{PAGENAME}} in pediatric patients. | ||
<!--Non–Guideline-Supported Use (Pediatric)--> | <!--Non–Guideline-Supported Use (Pediatric)--> | ||
|offLabelPedNoGuideSupport | |offLabelPedNoGuideSupport= | ||
There is limited information regarding <i>Off-Label Non–Guideline-Supported Use</i> of {{PAGENAME}} in pediatric patients. | There is limited information regarding <i>Off-Label Non–Guideline-Supported Use</i> of {{PAGENAME}} in pediatric patients. | ||
<!--Contraindications--> | <!--Contraindications--> | ||
|warnings=* For external use only | |||
|warnings=* | |||
flammable, keep away from fire and flame | |||
will produce serious gastric disturbances if taken internally | |||
Ask a doctor before use if you have deep puncture wounds or serious burns | |||
When using this product | |||
do not get into eyes or mucous membranes | |||
use only in a well-ventilated area | |||
Stop use and ask a doctor if condition persists or gets worse. | |||
Keep out of reach of children. In case of an accidental ingestion, contact a Poison Control Center immediately. | |||
|clinicalTrials=There is limited information regarding <i>Clinical Trial Experience</i> of {{PAGENAME}} in the drug label. | |clinicalTrials=There is limited information regarding <i>Clinical Trial Experience</i> of {{PAGENAME}} in the drug label. | ||
|postmarketing=There is limited information regarding <i>Postmarketing Experience</i> of {{PAGENAME}} in the drug label. | |postmarketing=There is limited information regarding <i>Postmarketing Experience</i> of {{PAGENAME}} in the drug label. | ||
|drugInteractions=* Drug | |drugInteractions=* Drug | ||
:* Description | :* Description | ||
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<!--Administration and Monitoring--> | <!--Administration and Monitoring--> | ||
|administration=* | |administration=* Topical | ||
|monitoring=There is limited information regarding <i>Monitoring</i> of {{PAGENAME}} in the drug label. | |monitoring=There is limited information regarding <i>Monitoring</i> of {{PAGENAME}} in the drug label. | ||
|IVCompat=There is limited information regarding <i>IV Compatibility</i> of {{PAGENAME}} in the drug label. | |IVCompat=There is limited information regarding <i>IV Compatibility</i> of {{PAGENAME}} in the drug label. | ||
<!--Overdosage--> | <!--Overdosage--> | ||
| | |drugBox=* {{chembox2 | ||
| Watchedfields = changed | |||
==== | | verifiedrevid = 477002700 | ||
| Name = Isopropyl alcohol | |||
| ImageFileL1 = 2-Propanol.svg | |||
| ImageNameL1 = Skeletal formula of isopropyl alcohol | |||
==== | | ImageFileR1 = Propan-2-ol-3D-balls.png | ||
| ImageNameR1 = Ball-and-stick model of isopropyl alcohol | |||
| PIN = 2-Propanol | |||
| IUPACName =isopropyl alcohol | |||
=== | | OtherNames = Propan-2-ol; Isopropanol; [[Rubbing alcohol]]; ''sec''-Propyl alcohol; ''s''-Propanol; iPrOH; IPA | ||
| Section1 = {{Chembox Identifiers | |||
| ChEBI_Ref = {{ebicite|correct|EBI}} | |||
| ChEBI = 17824 | |||
< | | SMILES = CC(O)C | ||
| UNII_Ref = {{fdacite|correct|FDA}} | |||
< | | UNII = ND2M416302 | ||
| | | UNNumber = 1219 | ||
| ChEMBL_Ref = {{ebicite|correct|EBI}} | |||
| ChEMBL = 582 | |||
| StdInChI_Ref = {{stdinchicite|correct|chemspider}} | |||
| StdInChI = 1S/C3H8O/c1-3(2)4/h3-4H,1-2H3 | |||
| StdInChIKey_Ref = {{stdinchicite|correct|chemspider}} | |||
| StdInChIKey = KFZMGEQAYNKOFK-UHFFFAOYSA-N | |||
| CASNo = 67-63-0 | |||
| CASNo_Ref = {{cascite|correct|CAS}} | |||
| ChemSpiderID_Ref = {{chemspidercite|correct|chemspider}} | |||
| ChemSpiderID = 3644 | |||
| PubChem = 3776 | |||
| RTECS = NT8050000 | |||
| KEGG_Ref = {{keggcite|correct|kegg}} | |||
| KEGG = D00137 | |||
| ATCCode_prefix = D08 | |||
| ATCCode_suffix = AX05 | |||
}} | |||
| Section2 = {{Chembox Properties | |||
| C=3|H=8|O=1 | |||
| Appearance = Colorless liquid | |||
| Density = 0.786 g/cm<sup>3</sup> (20 °C) | |||
| Solubility = [[miscible]] | |||
| SolubleOther = miscible in [[benzene]], [[chloroform]], [[ethanol]], [[ether]], [[glycerin]] <br> soluble in [[acetone]] <br> insoluble in [[salt]] solutions | |||
| MeltingPtC = −89 | |||
| BoilingPtC = 82.6 | |||
| pKa = 16.5<ref>{{cite journal|author=Reeve, W.; Erikson, C.M.; Aluotto, P.F. |journal=Can. J. Chem.|year=1979|volume=57|issue=20|pages= 2747|doi=10.1139/v79-444|title=A new method for the determination of the relative acidities of alcohols in alcoholic solutions. The nucleophilicities and competitive reactivities of alkoxides and phenoxides}}</ref> | |||
| Viscosity = 2.86 c[[Poise|P]] at 15 °C<br>1.96 c[[Poise|P]] at 25 °C<ref name = yaws>{{cite book | title = Chemical Properties Handbook | author = Yaws, C.L. | publisher = [[McGraw-Hill]] | year = 1999 | isbn = 0-07-073401-1}}</ref><br>1.77 c[[Poise|P]] at 30 °C<ref name = yaws/> | |||
| Dipole = 1.66 [[Debye|D]] (gas) | |||
| RefractIndex = 1.3776 | |||
}} | |||
|mechAction=* | |mechAction=* | ||
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|howSupplied=* | |howSupplied=* | ||
|packLabel=<!--Patient Counseling Information--> | |packLabel=<!--Patient Counseling Information--> | ||
|fdaPatientInfo= | |fdaPatientInfo=apply to skin directly or with clean gauze, cotton or swab. | ||
for rubbing, apply liberally and rub with hands. | |||
|alcohol=* Alcohol-{{PAGENAME}} interaction has not been established. Talk to your doctor about the effects of taking alcohol with this medication. | |alcohol=* Alcohol-{{PAGENAME}} interaction has not been established. Talk to your doctor about the effects of taking alcohol with this medication. | ||
<!--Brand Names--> | <!--Brand Names--> | ||
|brandNames=* | |brandNames=* ISOPROPYL RUBBING ALCOHOL®<ref>{{Cite web | title =ISOPROPYL RUBBING ALCOHOL - isopropyl alcohol liquid | url = http://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=ff80a29c-ed8b-4aa2-badf-f8d11172e52d}}</ref> | ||
<!--Look-Alike Drug Names--> | <!--Look-Alike Drug Names--> |
Revision as of 21:44, 28 January 2015
{{DrugProjectFormSinglePage |authorTag=Ammu Susheela, M.D. [1] |genericName=topical antimicrobial |aOrAn=a |drugClass=antiseptic |indicationType=treatment |indication=cuts, scrapes and minor muscular aches |adverseReactions=hypersensitivity |blackBoxWarningTitle=ConditionName: |blackBoxWarningBody=ConditionName:
- Content
|fdaLIADAdult=to decrease germs in minor cuts and scrapes.
helps relieve minor muscular aches due to exertion.
|offLabelAdultGuideSupport=
There is limited information regarding Off-Label Guideline-Supported Use of Isopropyl alcohol in adult patients.
|offLabelAdultNoGuideSupport=
There is limited information regarding Off-Label Non–Guideline-Supported Use of Isopropyl alcohol in adult patients.
|fdaLIADPed=
There is limited information regarding FDA-Labeled Use of Isopropyl alcohol in pediatric patients.
|offLabelPedGuideSupport=
There is limited information regarding Off-Label Guideline-Supported Use of Isopropyl alcohol in pediatric patients.
|offLabelPedNoGuideSupport=
There is limited information regarding Off-Label Non–Guideline-Supported Use of Isopropyl alcohol in pediatric patients.
|warnings=* For external use only
flammable, keep away from fire and flame will produce serious gastric disturbances if taken internally Ask a doctor before use if you have deep puncture wounds or serious burns When using this product
do not get into eyes or mucous membranes use only in a well-ventilated area Stop use and ask a doctor if condition persists or gets worse. Keep out of reach of children. In case of an accidental ingestion, contact a Poison Control Center immediately. |clinicalTrials=There is limited information regarding Clinical Trial Experience of Isopropyl alcohol in the drug label.
|postmarketing=There is limited information regarding Postmarketing Experience of Isopropyl alcohol in the drug label.
|drugInteractions=* Drug
- Description
|useInPregnancyFDA=* Pregnancy Category |useInPregnancyAUS=* Australian Drug Evaluation Committee (ADEC) Pregnancy Category
There is no Australian Drug Evaluation Committee (ADEC) guidance on usage of Isopropyl alcohol in women who are pregnant. |useInLaborDelivery=There is no FDA guidance on use of Isopropyl alcohol during labor and delivery. |useInNursing=There is no FDA guidance on the use of Isopropyl alcohol with respect to nursing mothers. |useInPed=There is no FDA guidance on the use of Isopropyl alcohol with respect to pediatric patients. |useInGeri=There is no FDA guidance on the use of Isopropyl alcohol with respect to geriatric patients. |useInGender=There is no FDA guidance on the use of Isopropyl alcohol with respect to specific gender populations. |useInRace=There is no FDA guidance on the use of Isopropyl alcohol with respect to specific racial populations. |useInRenalImpair=There is no FDA guidance on the use of Isopropyl alcohol in patients with renal impairment. |useInHepaticImpair=There is no FDA guidance on the use of Isopropyl alcohol in patients with hepatic impairment. |useInReproPotential=There is no FDA guidance on the use of Isopropyl alcohol in women of reproductive potentials and males. |useInImmunocomp=There is no FDA guidance one the use of Isopropyl alcohol in patients who are immunocompromised.
|administration=* Topical |monitoring=There is limited information regarding Monitoring of Isopropyl alcohol in the drug label.
|IVCompat=There is limited information regarding IV Compatibility of Isopropyl alcohol in the drug label.
|drugBox=*
Template:Chembox entryTemplate:Chembox entryTemplate:Chembox entryTemplate:Chembox entryTemplate:Chembox entryTemplate:Chembox entryTemplate:Chembox entryTemplate:Chembox entryTemplate:Chembox entryTemplate:Chembox entryTemplate:Chembox entryTemplate:Chembox entryTemplate:Chembox entryTemplate:Chembox entryTemplate:Chembox entryTemplate:Chembox entryTemplate:Chembox entryTemplate:Chembox entryTemplate:Chembox entryTemplate:Chembox entryTemplate:Chembox entryTemplate:Chembox entryTemplate:Chembox entryTemplate:Chembox entryTemplate:Chembox entryTemplate:Chembox E numberTemplate:Chembox RTECSTemplate:Chembox UNNumberTemplate:Chembox AppearanceTemplate:Chembox DensityTemplate:Chembox MeltingPtTemplate:Chembox BoilingPtTemplate:Chembox SolubilityInWaterTemplate:Chembox SolubilityTemplate:Chembox pKaTemplate:Chembox RefractIndexTemplate:Chembox ViscosityTemplate:Chembox DipoleTemplate:Chembox SupplementTemplate:Chembox header2 | Isopropyl alcohol | |
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Identifiers | |
3D model (JSmol)
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ChEBI | |
ChEMBL | |
ChemSpider | |
ECHA InfoCard | Lua error in Module:Wikidata at line 879: attempt to index field 'wikibase' (a nil value). Lua error in Module:Wikidata at line 879: attempt to index field 'wikibase' (a nil value). |
KEGG | |
PubChem CID
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UNII | |
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Properties | |
C3H8O | |
Molar mass | 60.10 g·mol−1 |
Template:Chembox header2 | Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa) Infobox disclaimer and references |
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}}
{{#subobject:
|Label Page=Isopropyl alcohol |Label Name=Isopropyl alcohol11.png
}}
{{#subobject:
|Label Page=Isopropyl alcohol |Label Name=Isopropyl alcohol11.png
}}
- ↑ Reeve, W.; Erikson, C.M.; Aluotto, P.F. (1979). "A new method for the determination of the relative acidities of alcohols in alcoholic solutions. The nucleophilicities and competitive reactivities of alkoxides and phenoxides". Can. J. Chem. 57 (20): 2747. doi:10.1139/v79-444.
- ↑ 2.0 2.1 Yaws, C.L. (1999). Chemical Properties Handbook. McGraw-Hill. ISBN 0-07-073401-1.