Estrone and sus scrofa

Estrone and sus scrofa
Adult Indications & Dosage
Pediatric Indications & Dosage
Contraindications
Warnings & Precautions
Adverse Reactions
Drug Interactions
Use in Specific Populations
Administration & Monitoring
Overdosage
Pharmacology
Clinical Studies
How Supplied
Images
Patient Counseling Information
Precautions with Alcohol
Brand Names
Look-Alike Names

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Ammu Susheela, M.D. [2]

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Overview

Estrone and sus scrofa is a hormone analog that is FDA approved for the treatment of for temporary relief of breast tenderness, hot flashes, irregular periods, mood swings, anxiety, headaches, and nervousness.. Common adverse reactions include hypersensitivity.

Adult Indications and Dosage

FDA-Labeled Indications and Dosage (Adult)

• For temporary relief of breast tenderness, hot flashes, irregular periods, mood swings, anxiety, headaches, and nervousness.
• 10 drops orally, 3 times a day.

Off-Label Use and Dosage (Adult)

Guideline-Supported Use

There is limited information regarding Off-Label Guideline-Supported Use of Estrone and sus scrofa in adult patients.

Non–Guideline-Supported Use

There is limited information regarding Off-Label Non–Guideline-Supported Use of Estrone and sus scrofa in adult patients.

Pediatric Indications and Dosage

FDA-Labeled Indications and Dosage (Pediatric)

There is limited information regarding Estrone and sus scrofa FDA-Labeled Indications and Dosage (Pediatric) in the drug label.

Off-Label Use and Dosage (Pediatric)

Guideline-Supported Use

There is limited information regarding Off-Label Guideline-Supported Use of Estrone and sus scrofa in pediatric patients.

Non–Guideline-Supported Use

There is limited information regarding Off-Label Non–Guideline-Supported Use of Estrone and sus scrofa in pediatric patients.

Contraindications

There is limited information regarding Estrone and sus scrofa Contraindications in the drug label.

Warnings

• If pregnant or breast-feeding, ask a health care professional before use.
• Keep out of reach of children. In case of overdose, get medical help or contact a Poison Control Center right away.
• Do not use if tamper evident seal is broken or missing.
• Store in cool, dry place

Adverse Reactions

Clinical Trials Experience

There is limited information regarding Estrone and sus scrofa Clinical Trials Experience in the drug label.

Postmarketing Experience

There is limited information regarding Estrone and sus scrofa Postmarketing Experience in the drug label.

Drug Interactions

There is limited information regarding Estrone and sus scrofa Drug Interactions in the drug label.

Use in Specific Populations

Pregnancy

Pregnancy Category (FDA): There is no FDA guidance on usage of Estrone and sus scrofa in women who are pregnant.
Pregnancy Category (AUS): There is no Australian Drug Evaluation Committee (ADEC) guidance on usage of Estrone and sus scrofa in women who are pregnant.

Labor and Delivery

There is no FDA guidance on use of Estrone and sus scrofa during labor and delivery.

Nursing Mothers

There is no FDA guidance on the use of Estrone and sus scrofa in women who are nursing.

Pediatric Use

There is no FDA guidance on the use of Estrone and sus scrofa in pediatric settings.

Geriatic Use

There is no FDA guidance on the use of Estrone and sus scrofa in geriatric settings.

Gender

There is no FDA guidance on the use of Estrone and sus scrofa with respect to specific gender populations.

Race

There is no FDA guidance on the use of Estrone and sus scrofa with respect to specific racial populations.

Renal Impairment

There is no FDA guidance on the use of Estrone and sus scrofa in patients with renal impairment.

Hepatic Impairment

There is no FDA guidance on the use of Estrone and sus scrofa in patients with hepatic impairment.

Females of Reproductive Potential and Males

There is no FDA guidance on the use of Estrone and sus scrofa in women of reproductive potentials and males.

Immunocompromised Patients

There is no FDA guidance one the use of Estrone and sus scrofa in patients who are immunocompromised.

Administration and Monitoring

Administration

• Oral

Monitoring

There is limited information regarding Estrone and sus scrofa Monitoring in the drug label.

IV Compatibility

There is limited information regarding the compatibility of Estrone and sus scrofa and IV administrations.

Overdosage

There is limited information regarding Estrone and sus scrofa overdosage. If you suspect drug poisoning or overdose, please contact the National Poison Help hotline (1-800-222-1222) immediately.

Pharmacology

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Estrone and sus scrofa
Systematic (IUPAC) name
(8R,9S,13S,14S)-3-hydroxy-13-methyl- 6,7,8,9,11,12,13,14,15,16- decahydrocyclopenta[a]phenanthren- 17- one
Identifiers
CAS number	53-16-7
ATC code	G03CA07 G03CC04 (WHO)
PubChem	5870
DrugBank	DB00655
Chemical data
Formula	Template:OrganicBox atomTemplate:OrganicBox atomTemplate:OrganicBoxTemplate:OrganicBoxTemplate:OrganicBoxTemplate:OrganicBoxTemplate:OrganicBoxTemplate:OrganicBoxTemplate:OrganicBoxTemplate:OrganicBoxTemplate:OrganicBoxTemplate:OrganicBoxTemplate:OrganicBoxTemplate:OrganicBoxTemplate:OrganicBoxTemplate:OrganicBox atomTemplate:OrganicBoxTemplate:OrganicBoxTemplate:OrganicBoxTemplate:OrganicBoxTemplate:OrganicBoxTemplate:OrganicBoxTemplate:OrganicBox
Mol. mass	270.366 g/mol
SMILES	eMolecules & PubChem
Physical data
Melt. point	254.5 °C (490 °F)
Pharmacokinetic data
Bioavailability	?
Protein binding	>95%
Metabolism	?
Half life	19 hours
Excretion	?
Therapeutic considerations
Pregnancy cat.	?
Legal status	[[Prescription drug|Template:Unicode-only]](US)
Routes	?

Mechanism of Action

There is limited information regarding Estrone and sus scrofa Mechanism of Action in the drug label.

Structure

There is limited information regarding Estrone and sus scrofa Structure in the drug label.

Pharmacodynamics

There is limited information regarding Estrone and sus scrofa Pharmacodynamics in the drug label.

Pharmacokinetics

There is limited information regarding Estrone and sus scrofa Pharmacokinetics in the drug label.

Nonclinical Toxicology

There is limited information regarding Estrone and sus scrofa Nonclinical Toxicology in the drug label.

Clinical Studies

There is limited information regarding Estrone and sus scrofa Clinical Studies in the drug label.

How Supplied

There is limited information regarding Estrone and sus scrofa How Supplied in the drug label.

Storage

• Store in cool, dry place.

Images

Drug Images

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Patient Counseling Information

• 10 drops orally, 3 times a day. Consult a physician for use in children under 12 years of age.

Precautions with Alcohol

Alcohol-Estrone and sus scrofa interaction has not been established. Talk to your doctor about the effects of taking alcohol with this medication.

Brand Names

• ESTROGEN ®

Look-Alike Drug Names

• A® — B®

Drug Shortage Status

Price

References

The contents of this FDA label are provided by the National Library of Medicine.