Etonogestrel

Etonogestrel
Adult Indications & Dosage
Pediatric Indications & Dosage
Contraindications
Warnings & Precautions
Adverse Reactions
Drug Interactions
Use in Specific Populations
Administration & Monitoring
Overdosage
Pharmacology
Clinical Studies
How Supplied
Images
Patient Counseling Information
Precautions with Alcohol
Brand Names
Look-Alike Names

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Gloria Picoy [2]

Disclaimer

WikiDoc MAKES NO GUARANTEE OF VALIDITY. WikiDoc is not a professional health care provider, nor is it a suitable replacement for a licensed healthcare provider. WikiDoc is intended to be an educational tool, not a tool for any form of healthcare delivery. The educational content on WikiDoc drug pages is based upon the FDA package insert, National Library of Medicine content and practice guidelines / consensus statements. WikiDoc does not promote the administration of any medication or device that is not consistent with its labeling. Please read our full disclaimer here.

Overview

Etonogestrel is {{{aOrAn}}} {{{drugClass}}} that is FDA approved for the {{{indicationType}}} of {{{indication}}}. Common adverse reactions include {{{adverseReactions}}}.

Adult Indications and Dosage

FDA-Labeled Indications and Dosage (Adult)

There is limited information regarding Etonogestrel FDA-Labeled Indications and Dosage (Adult) in the drug label.

Off-Label Use and Dosage (Adult)

Guideline-Supported Use

There is limited information regarding Off-Label Guideline-Supported Use of Etonogestrel in adult patients.

Non–Guideline-Supported Use

There is limited information regarding Off-Label Non–Guideline-Supported Use of Etonogestrel in adult patients.

Pediatric Indications and Dosage

FDA-Labeled Indications and Dosage (Pediatric)

There is limited information regarding Etonogestrel FDA-Labeled Indications and Dosage (Pediatric) in the drug label.

Off-Label Use and Dosage (Pediatric)

Guideline-Supported Use

There is limited information regarding Off-Label Guideline-Supported Use of Etonogestrel in pediatric patients.

Non–Guideline-Supported Use

There is limited information regarding Off-Label Non–Guideline-Supported Use of Etonogestrel in pediatric patients.

Contraindications

There is limited information regarding Etonogestrel Contraindications in the drug label.

Warnings

There is limited information regarding Etonogestrel Warnings' in the drug label.

Adverse Reactions

Clinical Trials Experience

There is limited information regarding Etonogestrel Clinical Trials Experience in the drug label.

Postmarketing Experience

There is limited information regarding Etonogestrel Postmarketing Experience in the drug label.

Drug Interactions

There is limited information regarding Etonogestrel Drug Interactions in the drug label.

Use in Specific Populations

Pregnancy

Pregnancy Category (FDA): There is no FDA guidance on usage of Etonogestrel in women who are pregnant.
Pregnancy Category (AUS): There is no Australian Drug Evaluation Committee (ADEC) guidance on usage of Etonogestrel in women who are pregnant.

Labor and Delivery

There is no FDA guidance on use of Etonogestrel during labor and delivery.

Nursing Mothers

There is no FDA guidance on the use of Etonogestrel in women who are nursing.

Pediatric Use

There is no FDA guidance on the use of Etonogestrel in pediatric settings.

Geriatic Use

There is no FDA guidance on the use of Etonogestrel in geriatric settings.

Gender

There is no FDA guidance on the use of Etonogestrel with respect to specific gender populations.

Race

There is no FDA guidance on the use of Etonogestrel with respect to specific racial populations.

Renal Impairment

There is no FDA guidance on the use of Etonogestrel in patients with renal impairment.

Hepatic Impairment

There is no FDA guidance on the use of Etonogestrel in patients with hepatic impairment.

Females of Reproductive Potential and Males

There is no FDA guidance on the use of Etonogestrel in women of reproductive potentials and males.

Immunocompromised Patients

There is no FDA guidance one the use of Etonogestrel in patients who are immunocompromised.

Administration and Monitoring

Administration

There is limited information regarding Etonogestrel Administration in the drug label.

Monitoring

There is limited information regarding Etonogestrel Monitoring in the drug label.

IV Compatibility

There is limited information regarding the compatibility of Etonogestrel and IV administrations.

Overdosage

There is limited information regarding Etonogestrel overdosage. If you suspect drug poisoning or overdose, please contact the National Poison Help hotline (1-800-222-1222) immediately.

Pharmacology

There is limited information regarding Etonogestrel Pharmacology in the drug label.

Mechanism of Action

There is limited information regarding Etonogestrel Mechanism of Action in the drug label.

Structure

There is limited information regarding Etonogestrel Structure in the drug label.

Pharmacodynamics

There is limited information regarding Etonogestrel Pharmacodynamics in the drug label.

Pharmacokinetics

There is limited information regarding Etonogestrel Pharmacokinetics in the drug label.

Nonclinical Toxicology

There is limited information regarding Etonogestrel Nonclinical Toxicology in the drug label.

Clinical Studies

There is limited information regarding Etonogestrel Clinical Studies in the drug label.

How Supplied

There is limited information regarding Etonogestrel How Supplied in the drug label.

Storage

There is limited information regarding Etonogestrel Storage in the drug label.

Images

Drug Images

{{#ask: Page Name::Etonogestrel |?Pill Name |?Drug Name |?Pill Ingred |?Pill Imprint |?Pill Dosage |?Pill Color |?Pill Shape |?Pill Size (mm) |?Pill Scoring |?NDC |?Drug Author |format=template |template=DrugPageImages |mainlabel=- |sort=Pill Name }}

Package and Label Display Panel

{{#ask: Label Page::Etonogestrel |?Label Name |format=template |template=DrugLabelImages |mainlabel=- |sort=Label Page }}

Patient Counseling Information

There is limited information regarding Etonogestrel Patient Counseling Information in the drug label.

Precautions with Alcohol

Alcohol-Etonogestrel interaction has not been established. Talk to your doctor about the effects of taking alcohol with this medication.

Brand Names

There is limited information regarding Etonogestrel Brand Names in the drug label.

Look-Alike Drug Names

There is limited information regarding Etonogestrel Look-Alike Drug Names in the drug label.

Drug Shortage Status

Price

References

The contents of this FDA label are provided by the National Library of Medicine.

Etonogestrel

Clinical data
Routes of administration	Subdermal as slow-release implant
ATC code	G03AC08 (WHO)
Legal status
Legal status	AU: S4 (Prescription only) UK: POM (Prescription only) US: ℞-only In general: ℞ (Prescription only)
Pharmacokinetic data
Metabolism	Hepatic (P450 3A4)
Elimination half-life	25 hours
Excretion	Urinary (majority) and fecal
Identifiers
IUPAC name 13-ethyl-17-ethynyl- 17-hydroxy-11-methylidene- 2,6,7,8,9,10,12,13,14,15,16,17- dodecahydro- 1H-cyclopenta[a] phenanthren-3-one
CAS Number	54048-10-1
PubChem CID	40976
DrugBank	APRD00766
E number	{{#property:P628}}
ECHA InfoCard	{{#property:P2566}}
Chemical and physical data
Formula	C22H28O2
Molar mass	324.457 g/mol

WikiDoc Resources for Etonogestrel
Articles
Most recent articles on Etonogestrel Most cited articles on Etonogestrel Review articles on Etonogestrel Articles on Etonogestrel in N Eng J Med, Lancet, BMJ
Media
Powerpoint slides on Etonogestrel Images of Etonogestrel Photos of Etonogestrel Podcasts & MP3s on Etonogestrel Videos on Etonogestrel
Evidence Based Medicine
Cochrane Collaboration on Etonogestrel Bandolier on Etonogestrel TRIP on Etonogestrel
Clinical Trials
Ongoing Trials on Etonogestrel at Clinical Trials.gov Trial results on Etonogestrel Clinical Trials on Etonogestrel at Google
Guidelines / Policies / Govt
US National Guidelines Clearinghouse on Etonogestrel NICE Guidance on Etonogestrel NHS PRODIGY Guidance FDA on Etonogestrel CDC on Etonogestrel
Books
Books on Etonogestrel
News
Etonogestrel in the news Be alerted to news on Etonogestrel News trends on Etonogestrel
Commentary
Blogs on Etonogestrel
Definitions
Definitions of Etonogestrel
Patient Resources / Community
Patient resources on Etonogestrel Discussion groups on Etonogestrel Patient Handouts on Etonogestrel Directions to Hospitals Treating Etonogestrel Risk calculators and risk factors for Etonogestrel
Healthcare Provider Resources
Symptoms of Etonogestrel Causes & Risk Factors for Etonogestrel Diagnostic studies for Etonogestrel Treatment of Etonogestrel
Continuing Medical Education (CME)
CME Programs on Etonogestrel
International
Etonogestrel en Espanol Etonogestrel en Francais
Business
Etonogestrel in the Marketplace Patents on Etonogestrel
Experimental / Informatics
List of terms related to Etonogestrel

Etonogestrel is a molecule used in hormonal contraceptives, most notably the subdermal implant Implanon.

Etonogestrel, the specific progestin used in NuvaRing, is the active metabolite of the inactive prodrug desogestrel, one of two third-generation progestins found in some epidemiological studies of combined oral contraceptive pills to be associated with a higher risk of venous thrombosis than combined oral contraceptive pills containing certain second-generation progestins. Because hormones are released continuously from NuvaRing, peak and total estrogen and progestin doses are significantly lower than with combined oral contraceptives, although it is not known whether this lowers the risk of blood clots.

See also

• Progestin
• Progestagen