Hydroa vacciniforme-like lymphoma other diagnostic studies: Difference between revisions

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{{CMG}}; {{JH}} {{AP}}
{{CMG}}; {{JH}} {{AP}}


===Histology===
==Histology==
Histology of the affected area commonly shows dense perivascular lymphocytic infiltration with reticulated degeneration of the epidermis. A study by Iwatsuki et al. detected [[Epstein-Barr virus]] (EBV) positive T-cells in the perivascular infiltration on biopsy in 28/29 patients tested. Antibody titers to EBV were measured in 14 of these patients and only five had abnormal antibody patterns consistent with chronic active EBV infection.<ref name="iwatsuki">{{cite journal|last=Iwatsuki|first=K|author2=Satoh M |author3=Yamamoto T |author4=Oono T |author5=Morizane S |author6=Ohtsuka M |author7=Xu ZG |author8=Suzuki D |author9=Tsuji K |displayauthors=9 |title=Pathogenic link between hydroa vacciniforme and Epstein-Barr virus-associated hematologic disorders.|journal=Arch Dermatol.|year=2006|volume=May;142(5)|pages=587–95}}</ref>
Histology of the affected area commonly shows dense perivascular lymphocytic infiltration with reticulated degeneration of the epidermis. A study by Iwatsuki et al. detected [[Epstein-Barr virus]] (EBV) positive T-cells in the perivascular infiltration on biopsy in 28/29 patients tested. Antibody titers to EBV were measured in 14 of these patients and only five had abnormal antibody patterns consistent with chronic active EBV infection.<ref name="iwatsuki">{{cite journal|last=Iwatsuki|first=K|author2=Satoh M |author3=Yamamoto T |author4=Oono T |author5=Morizane S |author6=Ohtsuka M |author7=Xu ZG |author8=Suzuki D |author9=Tsuji K |displayauthors=9 |title=Pathogenic link between hydroa vacciniforme and Epstein-Barr virus-associated hematologic disorders.|journal=Arch Dermatol.|year=2006|volume=May;142(5)|pages=587–95}}</ref>



Revision as of 22:25, 15 February 2015

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Jesus Rosario Hernandez, M.D. [2] Alberto Plate [3]

Histology

Histology of the affected area commonly shows dense perivascular lymphocytic infiltration with reticulated degeneration of the epidermis. A study by Iwatsuki et al. detected Epstein-Barr virus (EBV) positive T-cells in the perivascular infiltration on biopsy in 28/29 patients tested. Antibody titers to EBV were measured in 14 of these patients and only five had abnormal antibody patterns consistent with chronic active EBV infection.[1]

References

  1. Iwatsuki, K; Satoh M; Yamamoto T; Oono T; Morizane S; Ohtsuka M; Xu ZG; Suzuki D; Tsuji K (2006). "Pathogenic link between hydroa vacciniforme and Epstein-Barr virus-associated hematologic disorders". Arch Dermatol. May;142(5): 587–95.

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