WBR0386: Difference between revisions

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(Created page with "{{WBRQuestion |QuestionAuthor={{Rim}} |ExamType=USMLE Step 1 |MainCategory=Embryology |SubCategory=Renal |MainCategory=Embryology |SubCategory=Renal |MainCategory=Embryology |...")
 
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{{WBRQuestion
{{WBRQuestion
|QuestionAuthor={{Rim}}
|QuestionAuthor={{YD}} (Reviewed by {{YD}})
|ExamType=USMLE Step 1
|ExamType=USMLE Step 1
|MainCategory=Embryology
|MainCategory=Embryology
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|MainCategory=Embryology
|MainCategory=Embryology
|SubCategory=Renal
|SubCategory=Renal
|MainCategory=Embryology
|MainCategory=Embryology
|MainCategory=Embryology
|MainCategory=Embryology
|MainCategory=Embryology
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|MainCategory=Embryology
|MainCategory=Embryology
|SubCategory=Renal
|SubCategory=Renal
|Prompt=A researcher is attempting to create developmental inhibitors of embryological components to study the embryologic origins of various tissues. While studying kidney embryology, the researcher decides to inhibit the development of the ureteric bud. As a result of his experiment, which of the following renal structures will fail to develop?
|Prompt=A researcher discovers developmental inhibitors of embryological components that help him study embryologic origins of various human tissues. In one experiment, the researcher decides to inhibit the development of the ureteric bud. As a result of his experiment, which of the following nephron structures will fail to develop?
|Explanation=Ureteric bud is derived from the caudal end of the mesonephros. It gives rise to collecting ducts, renal pelvicalyceal system, and ureters. In contrast, the metanephros, which interacts with the ureteric bud, gives rise to renal structures such as glomerulus, proximal convoluted tubules, loop of Henle through the distal convoluted tubules.
|Explanation=The ureteric bud is derived from the caudal end of the mesonephros. It gives rise to the collecting ducts, the renal pelvicalyceal system, and the ureters. In contrast, the metanephros, which interacts with the ureteric bud, gives rise to renal structures, such as the glomerulus, proximal convoluted tubules, loop of Henle, and the distal convoluted tubules.
 
Educational Objective:
The metanephros and ureteric bud interact to give rise to renal and urinary structures.  The metanephros gives rise to glomerulus through the distal convoluted tubule, while the ureteric bud gives rise to collecting duct, pelvicalyceal system, and the ureters.
 
|AnswerA=Glomeruli
|AnswerA=Glomeruli
|AnswerAExp=Glomerulus is derived from the metanephros
|AnswerAExp=The glomerulus is derived from the metanephros.
|AnswerB=Cortical proximal convoluted tubule (PCT)
|AnswerB=Cortical proximal convoluted tubule (PCT)
|AnswerBExp=PCT is derived from the metanephros
|AnswerBExp=The proximal convoluted tubule is derived from the metanephros.
|AnswerC=Loop of Henle in the medulla
|AnswerC=Loop of Henle in the medulla
|AnswerCExp=Loop of Henle is derived from the metanephros
|AnswerCExp=Loop of Henle is derived from the metanephros.
|AnswerD=Cortical distal convoluted tubules (DCT)
|AnswerD=Cortical distal convoluted tubules
|AnswerDExp=DCT is derived from the metanephros
|AnswerDExp=The distal convoluted tubules are derived from the metanephros.
|AnswerE=Medullary collecting ducts
|AnswerE=Medullary collecting ducts
|AnswerEExp=Collecting ducts are derived from the ureteric bud.
|AnswerEExp=Collecting ducts are derived from the ureteric bud.
|EducationalObjectives=The metanephros and ureteric bud interact to give rise to the renal and urinary structures. The metanephros gives rise to the glomerulus through the distal convoluted tubule, while the ureteric bud gives rise to the collecting duct, pelvicalyceal system, and the ureters.
|References=First Aid 2014 page 522
|RightAnswer=E
|RightAnswer=E
|Approved=No
|WBRKeyword=Ureteric bud, Kidney embryology, Metanephros, Metanephric mesenchyme, Collecting ducts, Experiment, Developmental inhibitor, Nephron
|Approved=Yes
}}
}}

Revision as of 21:01, 16 February 2015
Author [[PageAuthor::Yazan Daaboul, M.D. (Reviewed by Yazan Daaboul, M.D.)]]
Exam Type ExamType::USMLE Step 1
Main Category MainCategory::Embryology
Sub Category SubCategory::Renal
Prompt [[Prompt::A researcher discovers developmental inhibitors of embryological components that help him study embryologic origins of various human tissues. In one experiment, the researcher decides to inhibit the development of the ureteric bud. As a result of his experiment, which of the following nephron structures will fail to develop?]]
Answer A AnswerA::Glomeruli
Answer A Explanation AnswerAExp::The glomerulus is derived from the metanephros.
Answer B AnswerB::Cortical proximal convoluted tubule (PCT)
Answer B Explanation AnswerBExp::The proximal convoluted tubule is derived from the metanephros.
Answer C AnswerC::Loop of Henle in the medulla
Answer C Explanation AnswerCExp::Loop of Henle is derived from the metanephros.
Answer D AnswerD::Cortical distal convoluted tubules
Answer D Explanation AnswerDExp::The distal convoluted tubules are derived from the metanephros.
Answer E AnswerE::Medullary collecting ducts
Answer E Explanation AnswerEExp::Collecting ducts are derived from the ureteric bud.
Right Answer RightAnswer::E
Explanation [[Explanation::The ureteric bud is derived from the caudal end of the mesonephros. It gives rise to the collecting ducts, the renal pelvicalyceal system, and the ureters. In contrast, the metanephros, which interacts with the ureteric bud, gives rise to renal structures, such as the glomerulus, proximal convoluted tubules, loop of Henle, and the distal convoluted tubules.

Educational Objective: The metanephros and ureteric bud interact to give rise to the renal and urinary structures. The metanephros gives rise to the glomerulus through the distal convoluted tubule, while the ureteric bud gives rise to the collecting duct, pelvicalyceal system, and the ureters.
References: First Aid 2014 page 522]]

Approved Approved::Yes
Keyword WBRKeyword::Ureteric bud, WBRKeyword::Kidney embryology, WBRKeyword::Metanephros, WBRKeyword::Metanephric mesenchyme, WBRKeyword::Collecting ducts, WBRKeyword::Experiment, WBRKeyword::Developmental inhibitor, WBRKeyword::Nephron
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