R-HCVAD regimen: Difference between revisions

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==Overview==
==Overview==
{{PAGENAME}} refers to a regimen consisting of [[rituximab]], [[cyclophosphamide]], [[vincristine]], [[Doxorubicin|doxorubicin (Adriamycin)]], and [[dexamethasone]] used to treat some forms of [[mantle cell lymphoma]].
{{PAGENAME}} refers to a regimen consisting of [[rituximab]], [[cyclophosphamide]], [[vincristine]], [[Doxorubicin|doxorubicin (Adriamycin)]], and [[dexamethasone]] used to treat some forms of [[mantle cell lymphoma]].<ref name="pmid16145068">{{cite journal| author=Romaguera JE, Fayad L, Rodriguez MA, Broglio KR, Hagemeister FB, Pro B et al.| title=High rate of durable remissions after treatment of newly diagnosed aggressive mantle-cell lymphoma with rituximab plus hyper-CVAD alternating with rituximab plus high-dose methotrexate and cytarabine. | journal=J Clin Oncol | year= 2005 | volume= 23 | issue= 28 | pages= 7013-23 | pmid=16145068 | doi=10.1200/JCO.2005.01.1825 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=16145068  }} </ref>


==Regimen==
==Regimen==
{{chemo|R|Rituximab}}
{{chemo|R|Rituximab}}


{{chemo|C|Cyclophosphamide}}
{{chemo|C|Cyclophosphamide}}
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==Indications==
==Indications==
* [[Mantle cell lymphoma]]
* [[Mantle cell lymphoma]]<ref name="pmid16145068">{{cite journal| author=Romaguera JE, Fayad L, Rodriguez MA, Broglio KR, Hagemeister FB, Pro B et al.| title=High rate of durable remissions after treatment of newly diagnosed aggressive mantle-cell lymphoma with rituximab plus hyper-CVAD alternating with rituximab plus high-dose methotrexate and cytarabine. | journal=J Clin Oncol | year= 2005 | volume= 23 | issue= 28 | pages= 7013-23 | pmid=16145068 | doi=10.1200/JCO.2005.01.1825 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=16145068  }} </ref>


==References==  
==References==  

Latest revision as of 17:14, 31 March 2015

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Aparna Vuppala, M.B.B.S. [2]

Synonyms and keywords: Rituximab-Hyper-Cyclophosphamide-Vincristine-Adriamycin-Dexamethasone regimen

Overview

R-HCVAD regimen refers to a regimen consisting of rituximab, cyclophosphamide, vincristine, doxorubicin (Adriamycin), and dexamethasone used to treat some forms of mantle cell lymphoma.[1]

Regimen

RRituximab

CCyclophosphamide

VVincristine (Oncovin)

ADoxorubicin (Adriamycin)

DDexamethasone

Indications

References

  1. 1.0 1.1 Romaguera JE, Fayad L, Rodriguez MA, Broglio KR, Hagemeister FB, Pro B; et al. (2005). "High rate of durable remissions after treatment of newly diagnosed aggressive mantle-cell lymphoma with rituximab plus hyper-CVAD alternating with rituximab plus high-dose methotrexate and cytarabine". J Clin Oncol. 23 (28): 7013–23. doi:10.1200/JCO.2005.01.1825. PMID 16145068.