Oxetacaine

Oxetacaine

Clinical data
AHFS/Drugs.com	International Drug Names
Routes of administration	Oral, topical
ATC code	C05AD06 (WHO)
Pharmacokinetic data
Elimination half-life	1 hour
Identifiers
IUPAC name 2,2'-(2-hydroxyethylimino)bis [N-(1,1-dimethyl-2- phenylethyl)-N-methylacetamide]
CAS Number	126-27-2 N
PubChem CID	4621
ChemSpider	4460 Y
UNII	IP8QT76V17
KEGG	D01152 Y
ChEMBL	ChEMBL127592 Y
E number	{{#property:P628}}
ECHA InfoCard	{{#property:P2566}}
Chemical and physical data
Formula	C28H41N3O3
Molar mass	467.643 g/mol
3D model (JSmol)	Interactive image
SMILES O=C(N(C(C)(C)Cc1ccccc1)C)CN(CCO)CC(=O)N(C(Cc2ccccc2)(C)C)C
InChI InChI=1S/C28H41N3O3/c1-27(2,19-23-13-9-7-10-14-23)29(5)25(33)21-31(17-18-32)22-26(34)30(6)28(3,4)20-24-15-11-8-12-16-24/h7-16,32H,17-22H2,1-6H3 Y Key:FTLDJPRFCGDUFH-UHFFFAOYSA-N Y
NY (what is this?)  (verify)

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Oxetacaine (INN, also known as oxethazaine) is a potent local anesthetic. It is administered orally (usually in combination with an antacid) for the relief of pain associated with peptic ulcer disease or esophagitis. It is also used topically in the management of hemorrhoid pain. Oral oxetacaine preparations are available in several countries, including India, South Africa, Japan and Brazil, but not the United States.

Unlike most local anesthetics, oxetacaine is active even in strongly acidic conditions.