Revision as of 17:28, 8 April 2015

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview=

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Fluspirilene
Clinical data
Routes of; administration	IM
ATC code	N05AG01 (WHO) ;
Legal status
Legal status	US: ℞-only ;
Identifiers
	IUPAC name 8-[4,4-bis(4-fluorophenyl)butyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one;
CAS Number	1841-19-6;
PubChem CID	3396;
E number	{{#property:P628}}
ECHA InfoCard	{{#property:P2566}}Lua error in Module:EditAtWikidata at line 36: attempt to index field 'wikibase' (a nil value).
Chemical and physical data
Formula	C29H31F2N3O
Molar mass	475.573 g/mol

Fluspirilene is a diphenylbutylpiperidine antipsychotic drug, used for the treatment of schizophrenia. It is administered intramuscularly.

It was discovered at Janssen Pharmaceutica in 1963.

References

@@ Line 1: / Line 1: @@
 {{drugbox |
 | IUPAC_name = 8-[4,4-bis(4-fluorophenyl)butyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one
-| image = Fluspirilene.svg
+| image = Fluspirilene.png
 | width = 220
 | CAS_number = 1841-19-6
@@ Line 25: / Line 25: @@
 | routes_of_administration = IM
 }}
+__NOTOC__
+{{SI}}
+{{CMG}}
+=Overview==
 '''Fluspirilene''' is a [[piperidine|diphenylbutylpiperidine]] [[antipsychotic]] [[drug]], used for the treatment of [[schizophrenia]]. It is administered [[Intramuscular injection|intramuscularly]].
@@ Line 30: / Line 35: @@
 ==References==
-* van Epen JH, Experience with fluspirilene (R 6218), a long-acting neuroleptic, Psychiatr Neurol Neurochir. 1970 Jul-Aug;73(4):277-84.
+{{reflist|2}}
-* Janssen PA, Niemegeers CJ, Schellekens KH, Lenaerts FM, Verbruggen FJ, van Nueten JM, Marsboom RH, Herin VV, Schaper WK., The pharmacology of fluspirilene (R 6218), a potent, long-acting and injectable neuroleptic drug, Arzneimittelforschung. 1970 Nov;20(11):1689-98.
 [[Category:Diphenylbutylpiperidine derivatives]]
+[[Category:Drug]]
-{{drug-stub}}
 {{Antipsychotics}}
-[[de:Fluspirilen]]

v t e Antipsychotics (neuroleptics) (N05A)
Typical	Benzamides: Levosulpiride • Nemonapride • Sulpiride • Sultopride • Tiapride • Veralipride; Butyrophenones: Azaperone • Benperidol • Bromperidol • Droperidol • Fluanisone • Haloperidol • Lenperone • Moperone • Pipamperone • Spiperone • Timiperone • Trifluperidol; Diphenylbutylpiperidines: Clopimozide • Fluspirilene • Penfluridol • Pimozide; Phenothiazines: Acepromazine • Acetophenazine • Butaperazine • Carphenazine • Chloracizine • Chlorproethazine • Chlorpromazine • Cyamemazine • Dixyrazine • Fluacizine • Fluphenazine • Levomepromazine/Methotrimeprazine • Mesoridazine • Perazine • Periciazine • Perphenazine • Piperacetazine • Pipotiazine • Prochlorperazine • Promazine • Promethazine • Propiomazine • Sulforidazine • Thiethylperazine • Thiopropazate • Thioproperazine • Thioridazine • Trifluoperazine • Triflupromazine; Thioxanthenes: Chlorprothixene • Clopenthixol • Flupentixol • Thiothixene • Zuclopenthixol; Tricyclics: Amoxapine • Butaclamol • Fluotracen • Loxapine • Metitepine/Methiothepin • Octoclothiepin • Trimipramine; Others: Prothipendyl
Atypical	Benzamides: Amisulpride • Remoxipride; Butyrophenones: Cinuperone • Setoperone; Benzo(iso)oxazole piperidines: Iloperidone • Ocaperidone • Paliperidone • Risperidone; Benzo(iso)thiazole piperazines: Lurasidone • Perospirone • Revospirone • Tiospirone • Ziprasidone; Diphenylbutylpiperazines: Amperozide; Phenylpiperazines: Aripiprazole • Bifeprunox • Elopiprazole • Umespirone; Tricyclics: Asenapine • Carpipramine • Clocapramine • Clotiapine • Clozapine • Fluperlapine • Gevotroline • Metitepine/Methiothepin • Mosapramine • NDMC • Olanzapine • Piquindone • Quetiapine • Tenilapine • Zotepine; Others: Blonanserin • Cariprazine • Molindone • Pimavanserin • Roxindole • Sarizotan • Sertindole • Spiramide
Others	Azacyclonol • Cannabidiol • D-Cycloserine • Lithium • Mifepristone • Oxypertine • Reserpine • Rimcazole • Secretin • Talnetant • Tetrabenazine • Vabicaserin
^#WHO-EM ^‡Withdrawn from market Clinical trials: ^†Phase III ^§Never to phase III Template:Psychology navs

Fluspirilene: Difference between revisions

Revision as of 17:28, 8 April 2015

Overview=

References

Navigation menu

Clinical data

Routes of administration	IM
ATC code	N05AG01 (WHO)
Legal status
Legal status	US: ℞-only
Identifiers
IUPAC name 8-[4,4-bis(4-fluorophenyl)butyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one
CAS Number	1841-19-6
PubChem CID	3396
E number	{{#property:P628}}
ECHA InfoCard	{{#property:P2566}}Lua error in Module:EditAtWikidata at line 36: attempt to index field 'wikibase' (a nil value).
Chemical and physical data
Formula	C₂₉H₃₁F₂N₃O
Molar mass	475.573 g/mol