Tiamulin: Difference between revisions

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Tiamulin
Clinical data
Routes of; administration	Oral
ATCvet code	Template:Infobox drug/formatATCvet; Template:Infobox drug/formatATCvet;
Legal status
Legal status	Veterinary use only;
Identifiers
	IUPAC name (4R,5S,6S,8R,9aR,10R)-5-Hydroxy-4,6,9,10-tetramethyl-1-oxo-6-vinyldecahydro-3a,9-propanocyclopenta[8]annulen-8-yl {[2-(diethylamino)ethyl]sulfanyl}acetate;
CAS Number	55297-95-5 ;
PubChem CID	656958;
ChemSpider	571196;
UNII	E38WZ4U54R;
ChEMBL	ChEMBL498466 ;
E number	{{#property:P628}}
ECHA InfoCard	{{#property:P2566}}Lua error in Module:EditAtWikidata at line 36: attempt to index field 'wikibase' (a nil value).
Chemical and physical data
Formula	C28H47NO4S
Molar mass	493.742 g/mol
3D model (JSmol)	Interactive image;
	SMILES CCN(CC)CCSCC(=O)O[C@@H]1C[C@@]([C@H]([C@@H]([C@@]23CC[C@H]([C@@]1([C@@H]2C(=O)CC3)C)C)C)O)(C)C=C;
	InChI InChI=1S/C28H47NO4S/c1-8-26(6)17-22(33-23(31)18-34-16-15-29(9-2)10-3)27(7)19(4)11-13-28(20(5)25(26)32)14-12-21(30)24(27)28/h8,19-20,22,24-25,32H,1,9-18H2,2-7H3/t19-,20+,22-,24+,25+,26-,27+,28+/m1/s1; Key:UURAUHCOJAIIRQ-QGLSALSOSA-N;
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Revision as of 18:42, 8 April 2015

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Tiamulin is a pleuromutilin antibiotic drug that is used in veterinary medicine particularly for pigs and poultry.^[1]^[2]

Tiamulin is a diterpene antimicrobial with a pleuromutilin chemical structure similar to that of valnemulin.^[3]

↑ HACCP: Tiamulin in Veterinary Medicine - Overview
↑ Long, Katherine S (April 2006). "Interaction of Pleuromutilin Derivatives with the Ribosomal Peptidyl Transferase Center" (PDF). Antimicrobial Agents and Chemotherapy. 50 (4): 1458–1462. doi:10.1128/AAC.50.4.1458-1462.2006. PMC 1426994. PMID 16569865. |first2= missing |last2= in Authors list (help); |first3= missing |last3= in Authors list (help); |first4= missing |last4= in Authors list (help)
↑ EMEA: Tiamulin Summary Report

@@ Line 3: / Line 3: @@
 | verifiedrevid = 376122925
 | IUPAC_name = (4''R'',5''S'',6''S'',8''R'',9a''R'',10''R'')-5-Hydroxy-4,6,9,10-tetramethyl-1-oxo-6-vinyldecahydro-3a,9-propanocyclopenta[8]annulen-8-yl {[2-(diethylamino)ethyl]sulfanyl}acetate
-| image = Tiamulin.png
+| image = Tiamulin.svg.png
 | width =
@@ Line 53: / Line 53: @@
 }}
 __NOTOC__
 {{SI}}
 {{CMG}}
 ==Overview==
 '''Tiamulin''' is a [[pleuromutilin]] [[antibiotic]] drug that is used in veterinary medicine particularly for pigs and poultry.<ref>[http://www.bioagrimix.com/haccp/html/tiamulin.htm HACCP: Tiamulin in Veterinary Medicine - Overview]</ref><ref>{{cite journal|last=Long|first=Katherine S|title=Interaction of Pleuromutilin Derivatives with the Ribosomal Peptidyl Transferase Center|journal=Antimicrobial Agents and Chemotherapy|date=April 2006|volume=50|issue=4|pages=1458–1462|url=http://aac.asm.org/cgi/reprint/50/4/1458.pdf|doi=10.1128/AAC.50.4.1458-1462.2006|pmid=16569865|first2=LH|first3=L|first4=B|pmc=1426994}}</ref>
@@ Line 66: / Line 63: @@
 {{reflist|2}}
-{{Protein synthesis inhibitor antibiotics}}
-[[Category:Pleuromutilin antibiotics]]
 [[Category:Alcohols]]
 [[Category:Ketones]]

Clinical data

Routes of administration	Oral
ATCvet code	Template:Infobox drug/formatATCvet Template:Infobox drug/formatATCvet
Legal status
Legal status	Veterinary use only
Identifiers
IUPAC name (4R,5S,6S,8R,9aR,10R)-5-Hydroxy-4,6,9,10-tetramethyl-1-oxo-6-vinyldecahydro-3a,9-propanocyclopenta[8]annulen-8-yl {[2-(diethylamino)ethyl]sulfanyl}acetate
CAS Number	55297-95-5^Y
PubChem CID	656958
ChemSpider	571196
UNII	E38WZ4U54R
ChEMBL	ChEMBL498466^N
E number	{{#property:P628}}
ECHA InfoCard	{{#property:P2566}}Lua error in Module:EditAtWikidata at line 36: attempt to index field 'wikibase' (a nil value).
Chemical and physical data
Formula	C₂₈H₄₇NO₄S
Molar mass	493.742 g/mol
3D model (JSmol)	Interactive image
SMILES CCN(CC)CCSCC(=O)O[C@@H]1C[C@@]([C@H]([C@@H]([C@@]23CC[C@H]([C@@]1([C@@H]2C(=O)CC3)C)C)C)O)(C)C=C
InChI InChI=1S/C28H47NO4S/c1-8-26(6)17-22(33-23(31)18-34-16-15-29(9-2)10-3)27(7)19(4)11-13-28(20(5)25(26)32)14-12-21(30)24(27)28/h8,19-20,22,24-25,32H,1,9-18H2,2-7H3/t19-,20+,22-,24+,25+,26-,27+,28+/m1/s1 Key:UURAUHCOJAIIRQ-QGLSALSOSA-N
^NY (what is this?) (verify)