Cefroxadine: Difference between revisions

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Cefroxadine
Clinical data
AHFS/Drugs.com	International Drug Names
Routes of; administration	Oral
ATC code	J01DB11 (WHO) ;
Legal status
Legal status	In general: ℞ (Prescription only);
Pharmacokinetic data
Elimination half-life	~1 hour
Excretion	Renal
Identifiers
	IUPAC name (6R,7R)-7-{[(2R)-2-amino-2-cyclohexa-1,4-dien-1-ylacetyl]amino}-3-methoxy-8-oxo-5-thia-1-azabicyclo[4.2.0]octane-2-carboxylic acid;
CAS Number	51762-05-1;
PubChem CID	443991;
ChemSpider	4447587;
UNII	B908C4MV2R;
KEGG	D01528;
ChEMBL	ChEMBL2104150;
E number	{{#property:P628}}
ECHA InfoCard	{{#property:P2566}}Lua error in Module:EditAtWikidata at line 36: attempt to index field 'wikibase' (a nil value).
Chemical and physical data
Formula	C16H19N3O5S
Molar mass	365.405 g/mol
3D model (JSmol)	Interactive image;
	SMILES O=C2N1/C(=C(/OC)CS[C@@H]1[C@@H]2NC(=O)[C@@H](C/3=C/C\C=C/C\3)N)C(=O)O;

VisualWikitext

Revision as of 20:22, 8 April 2015

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Cefroxadine (INN, trade names Oraspor and Cefthan-DS) is a cephalosporin antibiotic. It is structurally related to cefalexin, and both drugs share a similar antimicrobial pharmacodynamics|spectrum of activity.^[1]

It is available in Italy.^[2]

References

↑ Yasuda K, Kurashige S, Mitsuhashi S (July 1980). "Cefroxadine (CGP-9000), an orally active cephalosporin". Antimicrobial Agents and Chemotherapy. 18 (1): 105–10. PMC 283947. PMID 6998373.
↑ [No authors listed]. "Oraspor". Prontuario.it (in Italian). Elsevier. Retrieved 2010-07-31.

[1] Yasuda K, Kurashige S, Mitsuhashi S (July 1980). "Cefroxadine (CGP-9000), an orally active cephalosporin". Antimicrobial Agents and Chemotherapy. 18 (1): 105–10. PMC 283947. PMID 6998373.

[2] [No authors listed]. "Oraspor". Prontuario.it (in Italian). Elsevier. Retrieved 2010-07-31.

[1]

[2]

@@ Line 1: / Line 1: @@
 {{Drugbox
 | IUPAC_name = (6''R'',7''R'')-7-{[(2''R'')-2-amino-2-cyclohexa-1,4-dien-1-ylacetyl]amino}-3-methoxy-8-oxo-5-thia-1-azabicyclo[4.2.0]octane-2-carboxylic acid
-| image = Cefroxadine.svg
+| image = Cefroxadine.png
 <!--Clinical data-->
@@ Line 42: / Line 42: @@
 | InChIKey = RDMOROXKXONCAL-UEKVPHQBBX
 }}
-'''Cefroxadine''' ([[International Nonproprietary Name|INN]], trade names '''Oraspor''' and '''Cefthan-DS''') is a [[cephalosporin]] antibiotic. It is structurally related to [[cefalexin]], and both drugs share a similar [[antimicrobial pharmacodynamics|spectrum of activity]].<ref>{{cite journal |author=Yasuda K, Kurashige S, Mitsuhashi S |title=Cefroxadine (CGP-9000), an orally active cephalosporin |journal=[[Antimicrobial Agents and Chemotherapy]] |volume=18 |issue=1 |pages=105–10 |date=July 1980 |pmid=6998373 |pmc=283947}}</ref>
+              __NOTOC__
+{{SI}}
+{{CMG}}
+==Overview==
+'''Cefroxadine''' ([[International Nonproprietary Name|INN]], trade names '''Oraspor''' and '''Cefthan-DS''') is a [[cephalosporin]] antibiotic. It is structurally related to [[cefalexin]], and both drugs share a similar antimicrobial pharmacodynamics|spectrum of activity.<ref>{{cite journal |author=Yasuda K, Kurashige S, Mitsuhashi S |title=Cefroxadine (CGP-9000), an orally active cephalosporin |journal=[[Antimicrobial Agents and Chemotherapy]] |volume=18 |issue=1 |pages=105–10 |date=July 1980 |pmid=6998373 |pmc=283947}}</ref>
 It is available in Italy.<ref>{{cite web |url=http://www.prontuario.it/ORASPOR/?f=xuiqqmolyaqmxu |author=[No authors listed] |title=Oraspor |work=Prontuario.it |publisher=Elsevier |language=Italian |date= |accessdate=2010-07-31}}</ref>
 ==References==
+{{Reflist|2}}
-<references/>
 {{CephalosporinAntiBiotics}}
 [[Category:Cephalosporin antibiotics]]
-[[Category:Enantiopure drugs]]
+[[Category:Drug]]
-{{antibiotic-stub}}

v t e Antibacterials: cell wall disruption (J01C-J01D)
Internal to membrane/ (inhibit peptidoglycan subunit synthesis and transport)	Template:Navbox subgroup
Glycopeptide/ (inhibit PG chain elongation)	Vancomycin # (Oritavancin, Telavancin) · Teicoplanin (Dalbavancin) · Ramoplanin
Beta-lactams/ (inhibit cross-links with PBP)	Template:Navbox subgroup
Other	Template:Navbox subgroup
# = WHO-EM

Clinical data

AHFS/Drugs.com	International Drug Names
Routes of administration	Oral
ATC code	J01DB11 (WHO)
Legal status
Legal status	In general: ℞ (Prescription only)
Pharmacokinetic data
Elimination half-life	~1 hour
Excretion	Renal
Identifiers
IUPAC name (6R,7R)-7-{[(2R)-2-amino-2-cyclohexa-1,4-dien-1-ylacetyl]amino}-3-methoxy-8-oxo-5-thia-1-azabicyclo[4.2.0]octane-2-carboxylic acid
CAS Number	51762-05-1
PubChem CID	443991
ChemSpider	4447587
UNII	B908C4MV2R
KEGG	D01528
ChEMBL	ChEMBL2104150
E number	{{#property:P628}}
ECHA InfoCard	{{#property:P2566}}Lua error in Module:EditAtWikidata at line 36: attempt to index field 'wikibase' (a nil value).
Chemical and physical data
Formula	C₁₆H₁₉N₃O₅S
Molar mass	365.405 g/mol
3D model (JSmol)	Interactive image
SMILES O=C2N1/C(=C(/OC)CS[C@@H]1[C@@H]2NC(=O)[C@@H](C/3=C/C\C=C/C\3)N)C(=O)O

Cefroxadine: Difference between revisions

Revision as of 20:22, 8 April 2015

Overview

References

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