Troleandomycin: Difference between revisions

Troleandomycin
Clinical data
AHFS/Drugs.com	Multum Consumer Information
MedlinePlus	a604026
ATC code	J01FA08 (WHO) ;
Identifiers
	IUPAC name (3R,5R,6R,7S,8R,11R,12S,13R,14S,15S)-12-[(4-O-acetyl-2,6-dideoxy-3-O-methyl-α-L-arabino-hexopyranosyl)oxy]-14-{[2-O-acetyl-3,4,6-trideoxy-3-(dimethylamino)-β-D-xylo-hexopyranosyl]oxy}-5,7,8,11,13,15-hexamethyl-4,10-dioxo-1,9-dioxaspiro[2.13]hexadec-6-yl acetate;
CAS Number	2751-09-9 ;
PubChem CID	5284630;
DrugBank	DB01361 ;
ChemSpider	4447675 ;
UNII	C4DZ64560D;
KEGG	D01322 ;
ChEMBL	ChEMBL564085 ;
E number	{{#property:P628}}
ECHA InfoCard	{{#property:P2566}}Lua error in Module:EditAtWikidata at line 36: attempt to index field 'wikibase' (a nil value).
Chemical and physical data
Formula	C41H67NO15
Molar mass	813.968 g/mol
3D model (JSmol)	Interactive image;
	SMILES O=C(O[C@@H]4[C@@H](N(C)C)C[C@H](O[C@H]4O[C@@H]3[C@H]([C@H](O[C@@H]1O[C@H]([C@H](OC(=O)C)[C@@H](OC)C1)C)[C@H](C(=O)O[C@H](C)[C@H](C)[C@H](OC(=O)C)[C@H](C(=O)[C@]2(OC2)C[C@@H]3C)C)C)C)C)C;
	InChI InChI=1S/C41H67NO15/c1-19-17-41(18-49-41)38(46)23(5)34(53-27(9)43)21(3)25(7)52-39(47)24(6)35(56-32-16-31(48-14)36(26(8)51-32)54-28(10)44)22(4)33(19)57-40-37(55-29(11)45)30(42(12)13)15-20(2)50-40/h19-26,30-37,40H,15-18H2,1-14H3/t19-,20+,21-,22+,23+,24+,25+,26-,30-,31-,32-,33-,34-,35-,36-,37+,40-,41-/m0/s1 ; Key:LQCLVBQBTUVCEQ-MCQAQMIOSA-N ;
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VisualWikitext

Revision as of 13:27, 9 April 2015

Troleandomycin is a macrolide antibiotic. It is sold in Italy (branded Triocetin) and Turkey (branded Tekmisin).

Troleandomycin is a CYP3A4 inhibitor that may cause drug interactions.

Template:Antibiotic-stub

@@ Line 1: / Line 1: @@
-__NOTOC__
+{{Drugbox
+| Verifiedfields = changed
+| verifiedrevid = 470617807
+| IUPAC_name = (3''R'',5''R'',6''R'',7''S'',8''R'',11''R'',12''S'',13''R'',14''S'',15''S'')-12-[(4-''O''-acetyl-2,6-dideoxy-3-''O''-methyl-α-<small>L</small>-''arabino''-hexopyranosyl)oxy]-14-{[2-''O''-acetyl-3,4,6-trideoxy-3-(dimethylamino)-β-<small>D</small>-''xylo''-hexopyranosyl]oxy}-5,7,8,11,13,15-hexamethyl-4,10-dioxo-1,9-dioxaspiro[2.13]hexadec-6-yl acetate
+| image = troleandomycin.png
+<!--Clinical data-->
+| tradename =
+| Drugs.com = {{drugs.com|MTM|troleandomycin}}
+| MedlinePlus = a604026
+| pregnancy_AU = <!-- A / B1 / B2 / B3 / C / D / X -->
+| pregnancy_US = <!-- A / B            / C / D / X -->
+| pregnancy_category =
+| legal_AU = <!-- Unscheduled / S2 / S3 / S4 / S5 / S6 / S7 / S8 / S9 -->
+| legal_CA = <!--             / Schedule I, II, III, IV, V, VI, VII, VIII -->
+| legal_UK = <!-- GSL         / P       / POM / CD / Class A, B, C -->
+| legal_US = <!-- OTC                   / Rx-only  / Schedule I, II, III, IV, V -->
+| legal_status =
+| routes_of_administration =
+<!--Pharmacokinetic data-->
+| bioavailability =
+| protein_bound =
+| metabolism =
+| elimination_half-life =
+| excretion =
+<!--Identifiers-->
+| CAS_number_Ref = {{cascite|correct|??}}
+| CAS_number = 2751-09-9
+| ATC_prefix = J01
+| ATC_suffix = FA08
+| PubChem = 5284630
+| DrugBank_Ref = {{drugbankcite|correct|drugbank}}
+| DrugBank = DB01361
+| ChemSpiderID_Ref = {{chemspidercite|correct|chemspider}}
+| ChemSpiderID = 4447675
+| UNII_Ref = {{fdacite|correct|FDA}}
+| UNII = C4DZ64560D
+| KEGG_Ref = {{keggcite|changed|kegg}}
+| KEGG = D01322
+| ChEMBL_Ref = {{ebicite|changed|EBI}}
+| ChEMBL = 564085
+<!--Chemical data-->
+| C=41 | H=67 | N=1 | O=15
+| molecular_weight = 813.968 g/mol
+| smiles = O=C(O[C@@H]4[C@@H](N(C)C)C[C@H](O[C@H]4O[C@@H]3[C@H]([C@H](O[C@@H]1O[C@H]([C@H](OC(=O)C)[C@@H](OC)C1)C)[C@H](C(=O)O[C@H](C)[C@H](C)[C@H](OC(=O)C)[C@H](C(=O)[C@]2(OC2)C[C@@H]3C)C)C)C)C)C
+| InChI = 1/C41H67NO15/c1-19-17-41(18-49-41)38(46)23(5)34(53-27(9)43)21(3)25(7)52-39(47)24(6)35(56-32-16-31(48-14)36(26(8)51-32)54-28(10)44)22(4)33(19)57-40-37(55-29(11)45)30(42(12)13)15-20(2)50-40/h19-26,30-37,40H,15-18H2,1-14H3/t19-,20+,21-,22+,23+,24+,25+,26-,30-,31-,32-,33-,34-,35-,36-,37+,40-,41-/m0/s1
+| InChIKey = LQCLVBQBTUVCEQ-MCQAQMIOBT
+| StdInChI_Ref = {{stdinchicite|correct|chemspider}}
+| StdInChI = 1S/C41H67NO15/c1-19-17-41(18-49-41)38(46)23(5)34(53-27(9)43)21(3)25(7)52-39(47)24(6)35(56-32-16-31(48-14)36(26(8)51-32)54-28(10)44)22(4)33(19)57-40-37(55-29(11)45)30(42(12)13)15-20(2)50-40/h19-26,30-37,40H,15-18H2,1-14H3/t19-,20+,21-,22+,23+,24+,25+,26-,30-,31-,32-,33-,34-,35-,36-,37+,40-,41-/m0/s1
+| StdInChIKey_Ref = {{stdinchicite|correct|chemspider}}
+| StdInChIKey = LQCLVBQBTUVCEQ-MCQAQMIOSA-N
+}}
+'''Troleandomycin''' is a [[macrolide]] antibiotic. It is sold in [[Italy]] (branded '''Triocetin''') and [[Turkey]] (branded '''Tekmisin''').
+Troleandomycin is a [[CYP3A4]] [[enzyme inhibitor|inhibitor]] that may cause [[drug interaction]]s.
+{{Macrolides, lincosamides and streptogramins}}
+[[Category:Macrolide antibiotics]]
+{{antibiotic-stub}}

v t e Antibacterials for systemic use: macrolides, lincosamides and streptogramins (J01F)
Macrolides	Erythromycin - Spiramycin - Midecamycin - Oleandomycin - Roxithromycin - Josamycin - Troleandomycin - Clarithromycin - Azithromycin - Miocamycin - Rokitamycin - Dirithromycin - Flurithromycin - Telithromycin - Cethromycin
Lincosamides	Clindamycin - Lincomycin
Streptogramins	Pristinamycin - Quinupristin/dalfopristin

Troleandomycin: Difference between revisions

Revision as of 13:27, 9 April 2015

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