Pranlukast: Difference between revisions
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|IUPAC_name = ''N''-[4-oxo-2-(2''H''-tetrazol-5-yl)chromen-7-yl]-<br>4-(4-phenylbutoxy)benzamide | |IUPAC_name = ''N''-[4-oxo-2-(2''H''-tetrazol-5-yl)chromen-7-yl]-<br>4-(4-phenylbutoxy)benzamide | ||
| image= | | image=Pranlukast.png | ||
| CAS_number= | | CAS_number= | ||
| ATC_prefix=R03 | | ATC_prefix=R03 | ||
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| routes_of_administration= Oral | | routes_of_administration= Oral | ||
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==Overview== | |||
'''Pranlukast''' is a cysteinyl [[Leukotriene receptor antagonist|leukotriene receptor-1 antagonist]]. This drug works similarly to [[Merck & Co.]]'s [[Singulair]] ([[montelukast]]). | '''Pranlukast''' is a cysteinyl [[Leukotriene receptor antagonist|leukotriene receptor-1 antagonist]]. This drug works similarly to [[Merck & Co.]]'s [[Singulair]] ([[montelukast]]). | ||
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==References== | ==References== | ||
{{reflist|2} | |||
{{Asthma and copd rx}} | {{Asthma and copd rx}} | ||
[[Category:Leukotriene antagonists]] | [[Category:Leukotriene antagonists]] | ||
[[Category:Drug]] | |||
Revision as of 15:31, 10 April 2015
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| Clinical data | |
|---|---|
| Routes of administration | Oral |
| ATC code | |
| Pharmacokinetic data | |
| Metabolism | Hepatic (mainly CYP3A4)[1] |
| Elimination half-life | 1.5 hours[1] |
| Identifiers | |
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| PubChem CID | |
| E number | {{#property:P628}} |
| ECHA InfoCard | {{#property:P2566}}Lua error in Module:EditAtWikidata at line 36: attempt to index field 'wikibase' (a nil value). |
| Chemical and physical data | |
| Formula | C27H23N5O4 |
| Molar mass | 481.503 g/mol |
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WikiDoc Resources for Pranlukast |
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Most recent articles on Pranlukast |
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Ongoing Trials on Pranlukast at Clinical Trials.gov Clinical Trials on Pranlukast at Google
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US National Guidelines Clearinghouse on Pranlukast
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Patient resources on Pranlukast Discussion groups on Pranlukast Patient Handouts on Pranlukast Directions to Hospitals Treating Pranlukast Risk calculators and risk factors for Pranlukast
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Causes & Risk Factors for Pranlukast |
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Pranlukast is a cysteinyl leukotriene receptor-1 antagonist. This drug works similarly to Merck & Co.'s Singulair (montelukast).
Medications of this class, which go under a variety of names according to whether one looks at the American, British or European system of nomenclature, have as their primary function the antagonism of bronchospasm caused, principally in asthmatics, by an allergic reaction to accidentally or inadvertently encountered allergens.
Medications of this group are normally used as an adjunct to the standard therapy of inhaled steroids with inhaled long- and/or short-acting beta-agonists. There are several similar medications in the group; all appear to be equally effective.
References
{{reflist|2}
- ↑ 1.0 1.1 Nakade S, Ueda S, Ohno T, Nakayama K, Miyata Y, Yukawa E, Higuchi S (2006). "Population pharmacokinetics of pranlukast hydrate dry syrup in children with allergic rhinitis and bronchial asthma". Drug Metab Pharmacokinet. 21 (2): 133–9. PMID 16702733.
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