Tulathromycin: Difference between revisions

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{{Drugbox
{{Drugbox
| IUPAC_name       = (2''R'',3''S'',4''R'',5''R'',8''R'',10''R'',11''R'',12''S'',13''S'',14''R'')-13-<nowiki>[[</nowiki>2,6-dideoxy-3-C-methyl-3-''Ο''-methyl-4-''C''-[(propylamino)methyl]-α-<small>L</small>-ribo-hexopyrano-syl]oxy]-2-ethyl-3,4,10-trihydroxy-3,5,8,10,12,14-hexamethyl-11-<nowiki>[[</nowiki>3,4,6-trideoxy-3-(dimethylamino)-β-<small>D</small>-xylo-hexopyranosyl]-oxy]-1-oxa-6-azacyclopentadecan-15-one
| Watchedfields = changed
| image             = Tulathromycin.png
| verifiedrevid = 443440285
| CAS_number        = 217500-96-4
| IUPAC_name = (2''R'',3''S'',4''R'',5''R'',8''R'',10''R'',11''R'',12''S'',13''S'',14''R'')-13-<nowiki>[[</nowiki>2,6-dideoxy-3-C-methyl-3-''Ο''-methyl-4-''C''-[(propylamino)methyl]-α-<small>L</small>-ribo-hexopyrano-syl]oxy]-2-ethyl-3,4,10-trihydroxy-3,5,8,10,12,14-hexamethyl-11-<nowiki>[[</nowiki>3,4,6-trideoxy-3-(dimethylamino)-β-<small>D</small>-xylo-hexopyranosyl]-oxy]-1-oxa-6-azacyclopentadecan-15-one
| ATC_prefix        =  
| image = Tulathromycin.png
| ATC_suffix        =
 
| PubChem          =
<!--Clinical data-->
| DrugBank          =
| tradename =
| C=41|H=79|N=3|O=12
| Drugs.com = {{drugs.com|international|tulathromycin}}
| molecular_weight  = 806.08 g/mol
| pregnancy_AU = <!-- A / B1 / B2 / B3 / C / D / X -->
| bioavailability  =
| pregnancy_US = <!-- A / B            / C / D / X -->
| protein_bound    =
| pregnancy_category =   
| metabolism        =
| legal_AU = <!-- S2, S3, S4, S5, S6, S7, S8, S9 or Unscheduled-->
| elimination_half-life =
| legal_CA = <!-- Schedule I, II, III, IV, V, VI, VII, VIII -->
| excretion        =
| legal_UK = <!-- GSL, P, POM, CD, or Class A, B, C -->
| pregnancy_AU     = <!-- A / B1 / B2 / B3 / C / D / X -->
| legal_US = <!-- OTC / Rx-only / Schedule I, II, III, IV, V -->
| pregnancy_US     = <!-- A / B            / C / D / X -->
| legal_status =
| pregnancy_category=   
| routes_of_administration =
| legal_AU = <!-- S2, S3, S4, S5, S6, S7, S8, S9 or Unscheduled-->
 
| legal_CA = <!-- Schedule I, II, III, IV, V, VI, VII, VIII -->
<!--Pharmacokinetic data-->
| legal_UK = <!-- GSL, P, POM, CD, or Class A, B, C -->
| bioavailability = 
| legal_US = <!-- OTC / Rx-only / Schedule I, II, III, IV, V -->
| protein_bound = 
| legal_status     =  
| metabolism = 
| routes_of_administration =  
| elimination_half-life = 
| excretion = 
 
<!--Identifiers-->
| CAS_number = 217500-96-4
| ATCvet = yes
| ATC_prefix = J01
| ATC_suffix = FA94
| PubChem = 
| DrugBank_Ref = {{drugbankcite|correct|drugbank}}
| DrugBank = 
| ChemSpiderID_Ref = {{chemspidercite|correct|chemspider}}
| ChemSpiderID = 24583287
| UNII_Ref = {{fdacite|correct|FDA}}
| UNII = Q839I13422
| KEGG_Ref = {{keggcite|correct|kegg}}
| KEGG = D06258
 
<!--Chemical data-->
| C=41 | H=79 | N=3 | O=12
| molecular_weight = 806.08 g/mol
| smiles = CCCNCC1(C(OC(CC1(C)OC)OC2C(C(C(CC(NC(C(C(C(OC(=O)C2C)CC)(C)O)O)C)C)(C)O)OC3C(C(CC(O3)C)N(C)C)O)C)C)O
| StdInChI_Ref = {{stdinchicite|correct|chemspider}}
| StdInChI = 1S/C40H77N3O12/c1-15-17-41-21-40(49)27(8)52-30(20-38(40,10)50-14)54-32-24(5)34(55-36-31(44)28(43(12)13)18-23(4)51-36)37(9,47)19-22(3)42-26(7)33(45)39(11,48)29(16-2)53-35(46)25(32)6/h22-34,36,41-42,44-45,47-49H,15-21H2,1-14H3/t22-,23-,24+,25-,26-,27+,28+,29-,30+,31-,32+,33-,34-,36+,37-,38-,39-,40+/m1/s1
| StdInChIKey_Ref = {{stdinchicite|correct|chemspider}}
| StdInChIKey = HWATWVYEWMIMSO-FROLMUNOSA-N
}}
}}
{{SI}}


'''Tulathromycin''' is a [[macrolide antibiotic]] used to treat [[bovine respiratory disease]] (BRD) in cattle and [[swine respiratory disease]] in pigs. It is marketed by [[Pfizer|Pfizer Inc.]] under the tradename '''Draxxin'''.
'''Tulathromycin''' is a [[macrolide antibiotic]] used to treat [[bovine respiratory disease]] (BRD) in cattle and [[swine respiratory disease]] in pigs. It is marketed by [[Pfizer|Pfizer Inc.]] under the tradename '''Draxxin'''.
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*[http://www.draxxin.com/PAHimages/compliance_pdfs/US_EN_DR_compliance.pdf Pfizer monograph for Draxxin (tulathromycin)]
*[http://www.draxxin.com/PAHimages/compliance_pdfs/US_EN_DR_compliance.pdf Pfizer monograph for Draxxin (tulathromycin)]


 
{{Veterinary-med-stub}}


[[Category:Macrolide antibiotics]]
[[Category:Macrolide antibiotics]]
{{WH}}
{{WS}}

Revision as of 16:14, 10 April 2015

Tulathromycin
Clinical data
AHFS/Drugs.comInternational Drug Names
ATCvet code
Identifiers
CAS Number
ChemSpider
UNII
KEGG
E number{{#property:P628}}
ECHA InfoCard{{#property:P2566}}Lua error in Module:EditAtWikidata at line 36: attempt to index field 'wikibase' (a nil value).
Chemical and physical data
FormulaC41H79N3O12
Molar mass806.08 g/mol
3D model (JSmol)
  (verify)

Tulathromycin is a macrolide antibiotic used to treat bovine respiratory disease (BRD) in cattle and swine respiratory disease in pigs. It is marketed by Pfizer Inc. under the tradename Draxxin.

It is supplied as a solution for injection containing 100 mg of the drug. [1]

References

  1. Draxxin at draxxin.com

External links


Template:Veterinary-med-stub