Chlorphenoxamine: Difference between revisions
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{{ | {{Drugbox | ||
| IUPAC_name | | Verifiedfields = changed | ||
| image | | Watchedfields = changed | ||
| verifiedrevid = 447811372 | |||
| IUPAC_name = {2-[1-(4-chlorophenyl)-1-phenylethoxy]ethyl}dimethylamine | |||
| | | image = Chlorphenoxamine.svg | ||
| | |||
<!--Clinical data--> | |||
| tradename = | |||
| Drugs.com = {{drugs.com|international|chlorphenoxamine}} | |||
| pregnancy_category = | |||
| legal_status = | |||
| pregnancy_category= | |||
| | |||
| routes_of_administration = Oral, topical | | routes_of_administration = Oral, topical | ||
<!--Pharmacokinetic data--> | |||
| bioavailability = Well absorbed | |||
| protein_bound = | |||
| metabolism = Likely [[liver|hepatic]] | |||
| elimination_half-life = | |||
| excretion = [[Kidney|Renal]] | |||
<!--Identifiers--> | |||
| CAS_number_Ref = {{cascite|correct|??}} | |||
| CAS_number = 77-38-3 | |||
| CAS_supplemental = {{CAS|562-09-4}} | |||
| ATC_prefix = D04 | |||
| ATC_suffix = AA34 | |||
| ATC_supplemental = {{ATC|R06|AA06}} | |||
| PubChem = 6475 | |||
| DrugBank_Ref = {{drugbankcite|changed|drugbank}} | |||
| DrugBank = DB09007 | |||
| ChemSpiderID_Ref = {{chemspidercite|correct|chemspider}} | |||
| ChemSpiderID = 6230 | |||
| ChEMBL_Ref = {{ebicite|changed|EBI}} | |||
| ChEMBL = 2110774 | |||
| UNII_Ref = {{fdacite|correct|FDA}} | |||
| UNII = 3UVD77BP8R | |||
| KEGG_Ref = {{keggcite|correct|kegg}} | |||
| KEGG = D07198 | |||
<!--Chemical data--> | |||
| C=18 | H=22 | Cl=1 | N=1 | O=1 | |||
| molecular_weight = 303.826 g/mol | |||
| smiles = Clc1ccc(cc1)C(OCCN(C)C)(c2ccccc2)C | |||
| InChI = 1/C18H22ClNO/c1-18(21-14-13-20(2)3,15-7-5-4-6-8-15)16-9-11-17(19)12-10-16/h4-12H,13-14H2,1-3H3 | |||
| InChIKey = KKHPNPMTPORSQE-UHFFFAOYAK | |||
| StdInChI_Ref = {{stdinchicite|correct|chemspider}} | |||
| StdInChI = 1S/C18H22ClNO/c1-18(21-14-13-20(2)3,15-7-5-4-6-8-15)16-9-11-17(19)12-10-16/h4-12H,13-14H2,1-3H3 | |||
| StdInChIKey_Ref = {{stdinchicite|correct|chemspider}} | |||
| StdInChIKey = KKHPNPMTPORSQE-UHFFFAOYSA-N | |||
}} | }} | ||
{{ | '''Chlorphenoxamine''' ('''Phenoxene''') is an [[antihistamine]] and [[anticholinergic]] used as an [[antipruritic]]<ref>{{cite pmid|13967113}}</ref> and [[antiparkinsonian]]<ref>{{cite pmid|13779077}}</ref> agent. It is an analog of [[diphenhydramine]].<ref>H. Arnold, N. Brock, E. Kuhas, and D. Lorenz, Arzneimittel Forsch., 4, 189 (1954).</ref> | ||
== References == | |||
{{Reflist}} | |||
{{Antipruritics}} | {{Antipruritics}} | ||
{{Antiparkinsonian}} | |||
{{Antihistamines}} | {{Antihistamines}} | ||
{{Cholinergics}} | |||
{{Histaminergics}} | |||
[[Category:H1 receptor antagonists]] | [[Category:H1 receptor antagonists]] | ||
{{ | [[Category:Organochlorides]] | ||
[[Category:Ethers]] | |||
[[Category:Amines]] | |||
{{respiratory-system-drug-stub}} | |||
{{dermatologic-drug-stub}} | |||
{{nervous-system-drug-stub}} |
Revision as of 20:11, 10 April 2015
File:Chlorphenoxamine.svg | |
Clinical data | |
---|---|
AHFS/Drugs.com | International Drug Names |
Routes of administration | Oral, topical |
ATC code | |
Pharmacokinetic data | |
Bioavailability | Well absorbed |
Metabolism | Likely hepatic |
Excretion | Renal |
Identifiers | |
| |
CAS Number | |
PubChem CID | |
DrugBank | |
ChemSpider | |
UNII | |
KEGG | |
ChEMBL | |
E number | {{#property:P628}} |
ECHA InfoCard | {{#property:P2566}}Lua error in Module:EditAtWikidata at line 36: attempt to index field 'wikibase' (a nil value). |
Chemical and physical data | |
Formula | C18H22ClNO |
Molar mass | 303.826 g/mol |
3D model (JSmol) | |
| |
| |
(what is this?) (verify) |
Chlorphenoxamine (Phenoxene) is an antihistamine and anticholinergic used as an antipruritic[1] and antiparkinsonian[2] agent. It is an analog of diphenhydramine.[3]
References
- ↑ PMID 13967113 (PMID 13967113)
Citation will be completed automatically in a few minutes. Jump the queue or expand by hand - ↑ PMID 13779077 (PMID 13779077)
Citation will be completed automatically in a few minutes. Jump the queue or expand by hand - ↑ H. Arnold, N. Brock, E. Kuhas, and D. Lorenz, Arzneimittel Forsch., 4, 189 (1954).
Template:Antipruritics
Template:Antiparkinsonian
Template:Respiratory-system-drug-stub
Template:Dermatologic-drug-stub
Template:Nervous-system-drug-stub
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- H1 receptor antagonists
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