4-dimethylaminophenol: Difference between revisions
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==Overview== | ==Overview== | ||
'''4-Dimethylaminophenol''' (abbreviated in medical practice as DMAP) is an aromatic compound containing both [[phenol]] and [[amine]] functional groups. It has the molecular formula C<sub>8</sub>H<sub>11</sub>NO. | '''4-Dimethylaminophenol''' (abbreviated in medical practice as DMAP) is an aromatic compound containing both [[phenol]] and [[amine]] functional groups. It has the molecular formula C<sub>8</sub>H<sub>11</sub>NO. | ||
==Uses== | ==Uses== | ||
4-Dimethylaminophenol has been used as an [[antidote]] for [[cyanide poisoning]]. | 4-Dimethylaminophenol has been used as an [[antidote]] for [[cyanide poisoning]].It has also been shown to be effective in treating [[hydrogen sulfide]] toxicity. | ||
It works by generating [[methemoglobin]]. | It works by generating [[methemoglobin]]. | ||
This is suitable as an emergency treatment only; treatment must be followed up with [[sodium thiosulfate]] or [[cobalamin]]. | This is suitable as an emergency treatment only; treatment must be followed up with [[sodium thiosulfate]] or [[cobalamin]]. | ||
In an animal model, it has shown effectiveness when given [[Intramuscular injection|intramuscularly]]. | In an animal model, it has shown effectiveness when given [[Intramuscular injection|intramuscularly]].Though, [[intramuscular injection]] should be avoid due to the probability of [[Necrosis|muscular necrosis]] after injection. [[Intravenous injection]] is recommended in a dose of 250mg. | ||
==References== | ==References== | ||
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[[Category:Antidotes]] | [[Category:Antidotes]] | ||
[[Category:Phenols]] | [[Category:Phenols]] | ||
[[Category:Drug]] | [[Category:Drug]] | ||
Revision as of 20:35, 10 April 2015
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3D model (JSmol)
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| ECHA InfoCard | Lua error in Module:Wikidata at line 879: attempt to index field 'wikibase' (a nil value). Lua error in Module:Wikidata at line 879: attempt to index field 'wikibase' (a nil value). |
PubChem CID
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| Properties | |
| C8H11NO | |
| Molar mass | 137.179 g/mol |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). | |
 verify (what is  ?)
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
4-Dimethylaminophenol (abbreviated in medical practice as DMAP) is an aromatic compound containing both phenol and amine functional groups. It has the molecular formula C8H11NO.
Uses
4-Dimethylaminophenol has been used as an antidote for cyanide poisoning.It has also been shown to be effective in treating hydrogen sulfide toxicity.
It works by generating methemoglobin.
This is suitable as an emergency treatment only; treatment must be followed up with sodium thiosulfate or cobalamin.
In an animal model, it has shown effectiveness when given intramuscularly.Though, intramuscular injection should be avoid due to the probability of muscular necrosis after injection. Intravenous injection is recommended in a dose of 250mg.