Pentamycin: Difference between revisions
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{{Drugbox | {{Drugbox | ||
| IUPAC_name | | verifiedrevid = 464198156 | ||
| image | | IUPAC_name = (3R,4S,6S,8S,10R,12R,14R,15R,16R,17E,19E,21E,23E,25E,27S,28R)-4,6,8,10,12,14,15,16,27-nonahydroxy-3-[(1R)-1-hydroxyhexyl]-17,28-dimethyl-1-oxacyclooctacosa-17,19,21,23,25-pentaen-2-one | ||
| image = Pentamycin.png | |||
<!--Clinical data--> | |||
| tradename = | |||
| pregnancy_AU = <!-- A / B1 / B2 / B3 / C / D / X --> | |||
| pregnancy_US = <!-- A / B / C / D / X --> | |||
| pregnancy_category = | |||
| legal_AU = <!-- Unscheduled / S2 / S3 / S4 / S5 / S6 / S7 / S8 / S9 --> | |||
| legal_CA = <!-- / Schedule I, II, III, IV, V, VI, VII, VIII --> | |||
| legal_UK = <!-- GSL / P / POM / CD / Class A, B, C --> | |||
| legal_US = <!-- OTC / Rx-only / Schedule I, II, III, IV, V --> | |||
| | | legal_status = | ||
| pregnancy_AU | | routes_of_administration = Vaginal pessary | ||
| pregnancy_US | |||
| pregnancy_category= | <!--Pharmacokinetic data--> | ||
| legal_AU | | bioavailability = | ||
| legal_CA | | protein_bound = | ||
| legal_UK | | metabolism = | ||
| legal_US | | elimination_half-life = | ||
| legal_status | | excretion = | ||
| routes_of_administration = | |||
<!--Identifiers--> | |||
| CAS_number_Ref = {{cascite|correct|??}} | |||
| CAS_number = | |||
| ATC_prefix = G01 | |||
| ATC_suffix = AA11 | |||
| ChemSpiderID_Ref = {{chemspidercite|correct|chemspider}} | |||
| ChemSpiderID = 4445390 | |||
| StdInChI_Ref = {{stdinchicite|correct|chemspider}} | |||
| StdInChI = 1S/C35H58O12/c1-4-5-11-16-29(41)32-30(42)20-26(38)18-24(36)17-25(37)19-27(39)21-31(43)34(45)33(44)22(2)14-12-9-7-6-8-10-13-15-28(40)23(3)47-35(32)46/h6-10,12-15,23-34,36-45H,4-5,11,16-21H2,1-3H3/b7-6+,10-8+,12-9+,15-13+,22-14+/t23-,24+,25-,26+,27-,28+,29-,30+,31-,32-,33-,34-/m1/s1 | |||
| StdInChIKey_Ref = {{stdinchicite|correct|chemspider}} | |||
| StdInChIKey = AGJUUQSLGVCRQA-SWOUQTJZSA-N | |||
| PubChem = 5358751 | |||
| DrugBank_Ref = {{drugbankcite|correct|drugbank}} | |||
| DrugBank = | |||
<!--Chemical data--> | |||
| chemical_formula = | |||
| C=35 | H=58 | O=12 | |||
| molecular_weight = 670.82782 g/mol | |||
}} | }} | ||
__NOTOC__ | |||
{{SI}} | {{SI}} | ||
{{CMG}} | |||
==Overview== | ==Overview== | ||
'''Pentamycin''', also called '''fungichromin''', is a [[macrolide]] [[antibiotic]]. | '''Pentamycin''', also called '''fungichromin''', is a [[macrolide]] [[antibiotic]]. | ||
Pentamycin is a polyene antifungal antibiotic obtained from ''[[Streptomyces pentaticus]]''. It is used in the treatment of vaginal [[candidiasis]] and for the protozoal infection [[trichomoniasis]]. A 3 mg vaginal [[pessary]] is inserted once or twice daily for 5-10 days. | |||
== References == | |||
{{reflist|2}} | |||
{{Gynecological anti-infectives and antiseptics}} | {{Gynecological anti-infectives and antiseptics}} | ||
[[Category:Macrolide antibiotics]] | [[Category:Macrolide antibiotics]] | ||
[[Category:Drug]] | |||
Revision as of 13:36, 15 April 2015
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| Clinical data | |
|---|---|
| Routes of administration | Vaginal pessary |
| ATC code | |
| Identifiers | |
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| PubChem CID | |
| ChemSpider | |
| E number | {{#property:P628}} |
| ECHA InfoCard | {{#property:P2566}}Lua error in Module:EditAtWikidata at line 36: attempt to index field 'wikibase' (a nil value). |
| Chemical and physical data | |
| Formula | C35H58O12 |
| Molar mass | 670.82782 g/mol |
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| (verify) | |
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WikiDoc Resources for Pentamycin |
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Ongoing Trials on Pentamycin at Clinical Trials.gov Clinical Trials on Pentamycin at Google
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US National Guidelines Clearinghouse on Pentamycin
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Patient resources on Pentamycin Discussion groups on Pentamycin Patient Handouts on Pentamycin Directions to Hospitals Treating Pentamycin Risk calculators and risk factors for Pentamycin
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Causes & Risk Factors for Pentamycin |
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Experimental / Informatics |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Pentamycin, also called fungichromin, is a macrolide antibiotic. Pentamycin is a polyene antifungal antibiotic obtained from Streptomyces pentaticus. It is used in the treatment of vaginal candidiasis and for the protozoal infection trichomoniasis. A 3 mg vaginal pessary is inserted once or twice daily for 5-10 days.