Prednylidene: Difference between revisions

	WikiDoc Resources for Prednylidene
Articles
Most recent articles on Prednylidene Most cited articles on Prednylidene Review articles on Prednylidene Articles on Prednylidene in N Eng J Med, Lancet, BMJ
Media
Powerpoint slides on Prednylidene Images of Prednylidene Photos of Prednylidene Podcasts & MP3s on Prednylidene Videos on Prednylidene
Evidence Based Medicine
Cochrane Collaboration on Prednylidene Bandolier on Prednylidene TRIP on Prednylidene
Clinical Trials
Ongoing Trials on Prednylidene at Clinical Trials.gov Trial results on Prednylidene Clinical Trials on Prednylidene at Google
Guidelines / Policies / Govt
US National Guidelines Clearinghouse on Prednylidene NICE Guidance on Prednylidene NHS PRODIGY Guidance FDA on Prednylidene CDC on Prednylidene
Books
Books on Prednylidene
News
Prednylidene in the news Be alerted to news on Prednylidene News trends on Prednylidene
Commentary
Blogs on Prednylidene
Definitions
Definitions of Prednylidene
Patient Resources / Community
Patient resources on Prednylidene Discussion groups on Prednylidene Patient Handouts on Prednylidene Directions to Hospitals Treating Prednylidene Risk calculators and risk factors for Prednylidene
Healthcare Provider Resources
Symptoms of Prednylidene Causes & Risk Factors for Prednylidene Diagnostic studies for Prednylidene Treatment of Prednylidene
Continuing Medical Education (CME)
CME Programs on Prednylidene
International
Prednylidene en Espanol Prednylidene en Francais
Business
Prednylidene in the Marketplace Patents on Prednylidene
Experimental / Informatics
List of terms related to Prednylidene

Prednylidene
Clinical data
Synonyms	(8S,9S,10R,11S,13S,14S,17R)-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-16-methylidene-6,7,8,9,11,12,14,15-octahydrocyclopenta[a]phenanthren-3-one
ATC code	H02AB11 (WHO) ;
Identifiers
	IUPAC name (11β)-11,17,21-trihydroxy-16-methylenepregna-1,4-diene-3,20-dione;
CAS Number	599-33-7 ;
PubChem CID	20055008;
ChemSpider	16735979 ;
UNII	IF8PQP966U;
E number	{{#property:P628}}
ECHA InfoCard	{{#property:P2566}}Lua error in Module:EditAtWikidata at line 36: attempt to index field 'wikibase' (a nil value).
Chemical and physical data
Formula	C22H28O5
Molar mass	372.455
3D model (JSmol)	Interactive image;
	SMILES OCC(=O)[C@@]2(O)C(=C)C[C@H]3[C@@H]4CC\C1=C\C(=O)\C=C/[C@]1(C)[C@H]4[C@@H](O)C[C@]23C;
	InChI InChI=1S/C22H28O5/c1-12-8-16-15-5-4-13-9-14(24)6-7-20(13,2)19(15)17(25)10-21(16,3)22(12,27)18(26)11-23/h6-7,9,15-17,19,23,25,27H,1,4-5,8,10-11H2,2-3H3/t15-,16-,17-,19+,20-,21-,22-/m0/s1 ; Key:WSVOMANDJDYYEY-CWNVBEKCSA-N ;
(what is this?) (verify)

VisualWikitext

Latest revision as of 19:51, 15 April 2015

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Prednylidene is a glucocorticoid^[1] for systemic use.

Substitution at position 16 also leads to more potent corticosteroids. The additional steric bulk introduced by such substituents adjacent to the dihydroxyacetone side chain also protects that moiety against metabolic degradation.

Synthesis

Curvularia

References

↑ Buttgereit F, Brand MD, Burmester GR (July 1999). "Equivalent doses and relative drug potencies for non-genomic glucocorticoid effects: a novel glucocorticoid hierarchy". Biochem. Pharmacol. 58 (2): 363–8. doi:10.1016/S0006-2952(99)00090-8. PMID 10423179.
↑ Template:Cite doi

[pmid10423179-1] Buttgereit F, Brand MD, Burmester GR (July 1999). "Equivalent doses and relative drug potencies for non-genomic glucocorticoid effects: a novel glucocorticoid hierarchy". Biochem. Pharmacol. 58 (2): 363–8. doi:10.1016/S0006-2952(99)00090-8. PMID 10423179.

[2] Template:Cite doi

[1]

[2]

@@ Line 48: / Line 48: @@
 | synonyms = <small>(8''S'',9''S'',10''R'',11''S'',13''S'',14''S'',17''R'')-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-16-methylidene-6,7,8,9,11,12,14,15-octahydrocyclopenta[''a'']phenanthren-3-one</small>
 }}
+                     __NOTOC__
+{{SI}}
+{{CMG}}
+==Overview==
 '''Prednylidene''' is a [[glucocorticoid]]<ref name="pmid10423179">{{cite journal |author=Buttgereit F, Brand MD, Burmester GR |title=Equivalent doses and relative drug potencies for non-genomic glucocorticoid effects: a novel glucocorticoid hierarchy |journal=Biochem. Pharmacol. |volume=58 |issue=2 |pages=363–8 |date=July 1999 |pmid=10423179 |doi= 10.1016/S0006-2952(99)00090-8|url=http://linkinghub.elsevier.com/retrieve/pii/S0006-2952(99)00090-8}}</ref> for systemic use.
@@ Line 55: / Line 59: @@
 ==Synthesis==
 [[Curvularia]]
-[[File:Prednylidene synthesis.png|thumb|center|700px|Prednylidene synthesis:<ref>{{Cite doi|10.1016/S0040-4039(01)99336-0}}</ref>]]
+[[File:Prednylidene_synthesis.png|thumb|center|700px|Prednylidene synthesis:<ref>{{Cite doi|10.1016/S0040-4039(01)99336-0}}</ref>]]
 ==References==
@@ Line 61: / Line 65: @@
-{{Glucocorticoids}}
-{{Glucocorticoidics}}
 [[Category:Glucocorticoids]]
+[[Category:Drug]]
-{{systemic-hormonal-drug-stub}}

Prednylidene: Difference between revisions

Latest revision as of 19:51, 15 April 2015

Overview

Synthesis

References

Navigation menu