Tuberculin: Difference between revisions

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{{SI}}
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* Content


{{otheruses4|'''Tuberculin''', the antigen used in the ''tuberculin skin test'' for tuberculosis|information about the '''tuberculin skin test'''|Mantoux test}}
<!--Adult Indications and Dosage-->


==Overview==
<!--FDA-Labeled Indications and Dosage (Adult)-->
|fdaLIADAdult======Condition1=====


'''Tuberculin''' is an [[antigen]] used to aid in the [[diagnosis]] of [[tuberculosis]] infection. An infection with the [[bacterium]] that causes tuberculosis frequently leads to a sensitivity to these antigens. Tuberculin was discovered by [[Germany|German]] scientist and physician [[Robert Koch]] in 1890.
* Dosing Information


The original tuberculin discovered by Koch was a [[glycerine]] extract of the tubercle bacilli and was developed as a remedy for tuberculosis, but it was ineffective in this role.  [[Clemens von Pirquet]] discovered that patients who had previously received injections of horse serum or [[smallpox]] vaccine had quicker, more severe reactions to a second injection, and he coined the word ''[[allergy]]'' to describe this hypersensitivity reaction.  Soon thereafter von Pirquet discovered the same type of reaction took place in those infected with tuberculosis, and he thus found the utility of what would become the tuberculin skin test. The test used in the United States at present is referred to as the [[Mantoux test]], in the United Kingdom it is referred to as the [[Heaf test]]. Both of these tests use "Purified Protein Derivative", or "PPD", which is a tuberculin derivative.
:* Dosage


==See also==
=====Condition2=====
* [[tuberculosis]]
* [[Heaf test]]
* [[Mantoux test]]
* [http://www.webmd.com/a-to-z-guides/Tuberculin-Skin-Tests Tuberculin Skin Tests]


* Dosing Information


:* Dosage


[[Category:Immunology]]
=====Condition3=====
[[Category:Tuberculosis]]


[[de:Tuberkulin-Test]]
* Dosing Information
[[ko:투베르쿨린]]
[[ja:ツベルクリン]]
[[pl:Tuberkulina]]
[[sl:Tuberkulin]]


{{WH}}
:* Dosage
{{WS}}
 
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* Dosing Information
 
:* Dosage
 
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[[Category:Drug]]

Revision as of 14:45, 16 April 2015

Tuberculin
Black Box Warning
Adult Indications & Dosage
Pediatric Indications & Dosage
Contraindications
Warnings & Precautions
Adverse Reactions
Drug Interactions
Use in Specific Populations
Administration & Monitoring
Overdosage
Pharmacology
Clinical Studies
How Supplied
Images
Patient Counseling Information
Precautions with Alcohol
Brand Names
Look-Alike Names

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1];

Disclaimer

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Black Box Warning

ConditionName:
See full prescribing information for complete Boxed Warning.
ConditionName:
  • Content

Overview

Tuberculin is a {{{drugClass}}} that is FDA approved for the treatment of {{{indication}}}. There is a Black Box Warning for this drug as shown here. Common adverse reactions include .

Adult Indications and Dosage

FDA-Labeled Indications and Dosage (Adult)

Condition1
  • Dosing Information
  • Dosage
Condition2
  • Dosing Information
  • Dosage
Condition3
  • Dosing Information
  • Dosage
Condition4
  • Dosing Information
  • Dosage

Off-Label Use and Dosage (Adult)

Guideline-Supported Use

Condition1
  • Developed by:
  • Class of Recommendation:
  • Strength of Evidence:
  • Dosing Information
  • Dosage
Condition2

There is limited information regarding Off-Label Guideline-Supported Use of Tuberculin in adult patients.

Non–Guideline-Supported Use

Condition1
  • Dosing Information
  • Dosage
Condition2

There is limited information regarding Off-Label Non–Guideline-Supported Use of Tuberculin in adult patients.

Pediatric Indications and Dosage

FDA-Labeled Indications and Dosage (Pediatric)

Condition1
  • Dosing Information
  • Dosage
Condition2

There is limited information regarding FDA-Labeled Use of Tuberculin in pediatric patients.

Off-Label Use and Dosage (Pediatric)

Guideline-Supported Use

Condition1
  • Developed by:
  • Class of Recommendation:
  • Strength of Evidence:
  • Dosing Information
  • Dosage
Condition2

There is limited information regarding Off-Label Guideline-Supported Use of Tuberculin in pediatric patients.

Non–Guideline-Supported Use

Condition1
  • Dosing Information
  • Dosage
Condition2

There is limited information regarding Off-Label Non–Guideline-Supported Use of Tuberculin in pediatric patients.

Contraindications

  • Condition1

Warnings

ConditionName:
See full prescribing information for complete Boxed Warning.
ConditionName:
  • Content
  • Description

Precautions

  • Description

Adverse Reactions

Clinical Trials Experience

There is limited information regarding Clinical Trial Experience of Tuberculin in the drug label.

Body as a Whole
Cardiovascular
Digestive
Endocrine
Hematologic and Lymphatic
Metabolic and Nutritional
Musculoskeletal
Neurologic
Respiratory
Skin and Hypersensitivy Reactions
Special Senses
Urogenital
Miscellaneous

Postmarketing Experience

There is limited information regarding Postmarketing Experience of Tuberculin in the drug label.

Body as a Whole
Cardiovascular
Digestive
Endocrine
Hematologic and Lymphatic
Metabolic and Nutritional
Musculoskeletal
Neurologic
Respiratory
Skin and Hypersensitivy Reactions
Special Senses
Urogenital
Miscellaneous

Drug Interactions

  • Drug
  • Description

Use in Specific Populations

Pregnancy

Pregnancy Category (FDA):

  • Pregnancy Category


Pregnancy Category (AUS):

  • Australian Drug Evaluation Committee (ADEC) Pregnancy Category

There is no Australian Drug Evaluation Committee (ADEC) guidance on usage of Tuberculin in women who are pregnant.

Labor and Delivery

There is no FDA guidance on use of Tuberculin during labor and delivery.

Nursing Mothers

There is no FDA guidance on the use of Tuberculin with respect to nursing mothers.

Pediatric Use

There is no FDA guidance on the use of Tuberculin with respect to pediatric patients.

Geriatic Use

There is no FDA guidance on the use of Tuberculin with respect to geriatric patients.

Gender

There is no FDA guidance on the use of Tuberculin with respect to specific gender populations.

Race

There is no FDA guidance on the use of Tuberculin with respect to specific racial populations.

Renal Impairment

There is no FDA guidance on the use of Tuberculin in patients with renal impairment.

Hepatic Impairment

There is no FDA guidance on the use of Tuberculin in patients with hepatic impairment.

Females of Reproductive Potential and Males

There is no FDA guidance on the use of Tuberculin in women of reproductive potentials and males.

Immunocompromised Patients

There is no FDA guidance one the use of Tuberculin in patients who are immunocompromised.

Administration and Monitoring

Administration

  • Oral
  • Intravenous

Monitoring

There is limited information regarding Monitoring of Tuberculin in the drug label.

  • Description

IV Compatibility

There is limited information regarding IV Compatibility of Tuberculin in the drug label.

Overdosage

Acute Overdose

Signs and Symptoms

  • Description

Management

  • Description

Chronic Overdose

There is limited information regarding Chronic Overdose of Tuberculin in the drug label.

Pharmacology

There is limited information regarding Tuberculin Pharmacology in the drug label.

Mechanism of Action

Structure

File:Tuberculin01.png
This image is provided by the National Library of Medicine.

Pharmacodynamics

There is limited information regarding Pharmacodynamics of Tuberculin in the drug label.

Pharmacokinetics

There is limited information regarding Pharmacokinetics of Tuberculin in the drug label.

Nonclinical Toxicology

There is limited information regarding Nonclinical Toxicology of Tuberculin in the drug label.

Clinical Studies

There is limited information regarding Clinical Studies of Tuberculin in the drug label.

How Supplied

Storage

There is limited information regarding Tuberculin Storage in the drug label.

Images

Drug Images

{{#ask: Page Name::Tuberculin |?Pill Name |?Drug Name |?Pill Ingred |?Pill Imprint |?Pill Dosage |?Pill Color |?Pill Shape |?Pill Size (mm) |?Pill Scoring |?NDC |?Drug Author |format=template |template=DrugPageImages |mainlabel=- |sort=Pill Name }}

Package and Label Display Panel

{{#ask: Label Page::Tuberculin |?Label Name |format=template |template=DrugLabelImages |mainlabel=- |sort=Label Page }}

Patient Counseling Information

There is limited information regarding Patient Counseling Information of Tuberculin in the drug label.

Precautions with Alcohol

  • Alcohol-Tuberculin interaction has not been established. Talk to your doctor about the effects of taking alcohol with this medication.

Brand Names

Look-Alike Drug Names

Drug Shortage Status

Price

References

The contents of this FDA label are provided by the National Library of Medicine.

  1. ↑ Empty citation (help)
  2. ↑ "http://www.ismp.org". External link in |title= (help)

{{#subobject: 

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}}

{{#subobject: 

 |Label Page=Tuberculin
 |Label Name=Tuberculin11.png

}}

{{#subobject: 

 |Label Page=Tuberculin
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