Ulobetasol: Difference between revisions
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{{ | {{Drugbox | ||
| IUPAC_name = ( | | Verifiedfields = changed | ||
| image = Ulobetasol.png | | verifiedrevid = 470619490 | ||
| IUPAC_name = (6α,11β,16β)-21-chloro-6,9-difluoro-11,17-dihydroxy-16-methylpregna-1,4-diene-3,20-dione | |||
| image = Ulobetasol.png | |||
<!--Clinical data--> | |||
| tradename = | |||
| Drugs.com = {{drugs.com|CONS|ulobetasol}} | |||
| MedlinePlus = a601060 | |||
| pregnancy_AU = <!-- A / B1 / B2 / B3 / C / D / X --> | |||
| pregnancy_US = <!-- A / B / C / D / X --> | |||
| pregnancy_category = | |||
| legal_AU = <!-- Unscheduled / S2 / S3 / S4 / S8 --> | |||
| legal_UK = <!-- GSL / P / POM / CD --> | |||
| legal_US = <!-- OTC / Rx-only --> | |||
| legal_status = | |||
| routes_of_administration = | |||
<!--Pharmacokinetic data--> | |||
| bioavailability = | |||
| protein_bound = | |||
| metabolism = | |||
| elimination_half-life = | |||
| excretion = | |||
<!--Identifiers--> | |||
| CAS_number_Ref = {{cascite|changed|??}} | |||
| CAS_number = 98651-66-2 | | CAS_number = 98651-66-2 | ||
| ATC_prefix = D07 | | ATC_prefix = D07 | ||
| ATC_suffix = AC21 | | ATC_suffix = AC21 | ||
| PubChem = 5311167 | | PubChem = 5311167 | ||
| DrugBank_Ref = {{drugbankcite|correct|drugbank}} | |||
| DrugBank = | | DrugBank = | ||
| C=22 | H=27 | Cl=1 | F=2 | O=4 | | ChemSpiderID_Ref = {{chemspidercite|correct|chemspider}} | ||
| ChemSpiderID = 4470691 | |||
| UNII_Ref = {{fdacite|correct|FDA}} | |||
| UNII = 9P6159HM7T | |||
| KEGG_Ref = {{keggcite|correct|kegg}} | |||
| KEGG = D08660 | |||
| ChEMBL_Ref = {{ebicite|changed|EBI}} | |||
| ChEMBL = 1201360 | |||
<!--Chemical data--> | |||
| C=22 | H=27 | Cl=1 | F=2 | O=4 | |||
| molecular_weight = 428.897 | | molecular_weight = 428.897 | ||
| | | smiles = ClCC(=O)[C@]3(O)[C@]2(C[C@H](O)[C@]4(F)[C@@]/1(\C(=C/C(=O)\C=C\1)[C@@H](F)C[C@H]4[C@@H]2C[C@@H]3C)C)C | ||
| InChI = 1/C22H27ClF2O4/c1-11-6-13-14-8-16(24)15-7-12(26)4-5-19(15,2)21(14,25)17(27)9-20(13,3)22(11,29)18(28)10-23/h4-5,7,11,13-14,16-17,27,29H,6,8-10H2,1-3H3/t11-,13-,14-,16-,17-,19-,20-,21-,22-/m0/s1 | |||
| InChIKey = LEHFPXVYPMWYQD-XHIJKXOTBD | |||
| StdInChI_Ref = {{stdinchicite|correct|chemspider}} | |||
| StdInChI = 1S/C22H27ClF2O4/c1-11-6-13-14-8-16(24)15-7-12(26)4-5-19(15,2)21(14,25)17(27)9-20(13,3)22(11,29)18(28)10-23/h4-5,7,11,13-14,16-17,27,29H,6,8-10H2,1-3H3/t11-,13-,14-,16-,17-,19-,20-,21-,22-/m0/s1 | |||
| | | StdInChIKey_Ref = {{stdinchicite|correct|chemspider}} | ||
| StdInChIKey = LEHFPXVYPMWYQD-XHIJKXOTSA-N | |||
| | | synonyms = <small>(6''S'',8''S'',9''S'',10''S'',11''S'',13''S'',14''S'',16''S'',17''R'')-17-(2-Chloroacetyl)-6,9-difluoro-11,17-dihydroxy-10,13,16-trimethyl-6,7,8,11,12,14,15,16-octahydrocyclopenta[''a'']phenanthren-3-one</small> | ||
| | |||
| | |||
}} | }} | ||
__NOTOC__ | |||
{{SI}} | |||
{{CMG}} | |||
==Overview== | |||
'''Ulobetasol''' ([[International Nonproprietary Name|INN]]) or '''halobetasol''' ([[United States Adopted Name|USAN]]) is a [[corticosteroid]] used to treat [[psoriasis]]. It is a group I corticosteroid under the US classification, the most potent class of such drugs. Halobetasol propionate is usually supplied as a 0.05% topical cream. | |||
==References== | |||
{{reflist|2}} | |||
{{ | {{Glucocorticoids}} | ||
{{Glucocorticoidics}} | |||
[[Category:Glucocorticoids]] | [[Category:Glucocorticoids]] | ||
[[Category: | [[Category:Organofluorides]] | ||
[[Category:Organochlorides]] | |||
[[Category:Alcohols]] | |||
[[Category:Ketones]] | |||
[[Category:Drug]] |
Revision as of 15:07, 17 April 2015
Clinical data | |
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Synonyms | (6S,8S,9S,10S,11S,13S,14S,16S,17R)-17-(2-Chloroacetyl)-6,9-difluoro-11,17-dihydroxy-10,13,16-trimethyl-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-3-one |
AHFS/Drugs.com | Micromedex Detailed Consumer Information |
MedlinePlus | a601060 |
ATC code | |
Identifiers | |
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CAS Number | |
PubChem CID | |
ChemSpider | |
UNII | |
KEGG | |
ChEMBL | |
E number | {{#property:P628}} |
ECHA InfoCard | {{#property:P2566}}Lua error in Module:EditAtWikidata at line 36: attempt to index field 'wikibase' (a nil value). |
Chemical and physical data | |
Formula | C22H27ClF2O4 |
Molar mass | 428.897 |
3D model (JSmol) | |
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(what is this?) (verify) |
WikiDoc Resources for Ulobetasol |
Articles |
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Most recent articles on Ulobetasol |
Media |
Evidence Based Medicine |
Clinical Trials |
Ongoing Trials on Ulobetasol at Clinical Trials.gov Clinical Trials on Ulobetasol at Google
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Guidelines / Policies / Govt |
US National Guidelines Clearinghouse on Ulobetasol
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Books |
News |
Commentary |
Definitions |
Patient Resources / Community |
Patient resources on Ulobetasol Discussion groups on Ulobetasol Patient Handouts on Ulobetasol Directions to Hospitals Treating Ulobetasol Risk calculators and risk factors for Ulobetasol
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Healthcare Provider Resources |
Causes & Risk Factors for Ulobetasol |
Continuing Medical Education (CME) |
International |
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Business |
Experimental / Informatics |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Ulobetasol (INN) or halobetasol (USAN) is a corticosteroid used to treat psoriasis. It is a group I corticosteroid under the US classification, the most potent class of such drugs. Halobetasol propionate is usually supplied as a 0.05% topical cream.
References
- Pages with script errors
- Template:drugs.com link with non-standard subpage
- Articles with changed CASNo identifier
- Articles with changed EBI identifier
- E number from Wikidata
- ECHA InfoCard ID from Wikidata
- Chemical articles with unknown parameter in Infobox drug
- Chemical pages without DrugBank identifier
- Drugs with no legal status
- Drugboxes which contain changes to verified fields
- Glucocorticoids
- Organofluorides
- Organochlorides
- Alcohols
- Ketones
- Drug