Chlorothiazide (tablet): Difference between revisions

Chlorothiazide (tablet)
	Adult Indications & Dosage
	Pediatric Indications & Dosage
	Contraindications
	Warnings & Precautions
	Adverse Reactions
	Drug Interactions
	Use in Specific Populations
	Administration & Monitoring
	Overdosage
	Pharmacology
	Clinical Studies
	How Supplied
	Images
	Patient Counseling Information
	Precautions with Alcohol
	Brand Names
	Look-Alike Names

VisualWikitext

Revision as of 12:17, 12 May 2015

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Kiran Singh, M.D. [2]

Disclaimer

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Overview

Chlorothiazide (tablet) is a {{{drugClass}}} that is FDA approved for the treatment of {{{indication}}}. Common adverse reactions include .

Adult Indications and Dosage

FDA-Labeled Indications and Dosage (Adult)

Indications

Chlorothiazide is indicated as adjunctive therapy in edema associated with congestive heart failure, hepatic cirrhosis, and corticosteroid and estrogen therapy.

Chlorothiazide has also been found useful in edema due to various forms of renal dysfunction such as nephrotic syndrome, acute glomerulonephritis, and chronic renal failure.

Chlorothiazide is indicated in the management of hypertension either as the sole therapeutic agent or to enhance the effectiveness of other antihypertensive drugs in the more severe forms of hypertension.

Off-Label Use and Dosage (Adult)

Guideline-Supported Use

There is limited information regarding Off-Label Guideline-Supported Use of Chlorothiazide (tablet) in adult patients.

Non–Guideline-Supported Use

There is limited information regarding Off-Label Non–Guideline-Supported Use of Chlorothiazide (tablet) in adult patients.

Pediatric Indications and Dosage

FDA-Labeled Indications and Dosage (Pediatric)

There is limited information regarding FDA-Labeled Use of Chlorothiazide (tablet) in pediatric patients.

Off-Label Use and Dosage (Pediatric)

Guideline-Supported Use

There is limited information regarding Off-Label Guideline-Supported Use of Chlorothiazide (tablet) in pediatric patients.

Non–Guideline-Supported Use

There is limited information regarding Off-Label Non–Guideline-Supported Use of Chlorothiazide (tablet) in pediatric patients.

Contraindications

Condition1

Warnings

Description

Precautions

Description

Adverse Reactions

Clinical Trials Experience

There is limited information regarding Clinical Trial Experience of Chlorothiazide (tablet) in the drug label.

Body as a Whole

Cardiovascular

Digestive

Endocrine

Hematologic and Lymphatic

Metabolic and Nutritional

Musculoskeletal

Neurologic

Respiratory

Skin and Hypersensitivy Reactions

Special Senses

Urogenital

Miscellaneous

Postmarketing Experience

There is limited information regarding Postmarketing Experience of Chlorothiazide (tablet) in the drug label.

Body as a Whole

Cardiovascular

Digestive

Endocrine

Hematologic and Lymphatic

Metabolic and Nutritional

Musculoskeletal

Neurologic

Respiratory

Skin and Hypersensitivy Reactions

Special Senses

Urogenital

Miscellaneous

Drug Interactions

Drug

Description

Use in Specific Populations

Pregnancy

Pregnancy Category (FDA):

Pregnancy Category

Pregnancy Category (AUS):

Australian Drug Evaluation Committee (ADEC) Pregnancy Category

There is no Australian Drug Evaluation Committee (ADEC) guidance on usage of Chlorothiazide (tablet) in women who are pregnant.

Labor and Delivery

There is no FDA guidance on use of Chlorothiazide (tablet) during labor and delivery.

Nursing Mothers

There is no FDA guidance on the use of Chlorothiazide (tablet) with respect to nursing mothers.

Pediatric Use

There is no FDA guidance on the use of Chlorothiazide (tablet) with respect to pediatric patients.

Geriatic Use

There is no FDA guidance on the use of Chlorothiazide (tablet) with respect to geriatric patients.

Gender

There is no FDA guidance on the use of Chlorothiazide (tablet) with respect to specific gender populations.

Race

There is no FDA guidance on the use of Chlorothiazide (tablet) with respect to specific racial populations.

Renal Impairment

There is no FDA guidance on the use of Chlorothiazide (tablet) in patients with renal impairment.

Hepatic Impairment

There is no FDA guidance on the use of Chlorothiazide (tablet) in patients with hepatic impairment.

Females of Reproductive Potential and Males

There is no FDA guidance on the use of Chlorothiazide (tablet) in women of reproductive potentials and males.

Immunocompromised Patients

There is no FDA guidance one the use of Chlorothiazide (tablet) in patients who are immunocompromised.

Administration and Monitoring

Administration

Oral

Intravenous

Monitoring

There is limited information regarding Monitoring of Chlorothiazide (tablet) in the drug label.

Description

IV Compatibility

There is limited information regarding IV Compatibility of Chlorothiazide (tablet) in the drug label.

Overdosage

Acute Overdose

Signs and Symptoms

Description

Management

Description

Chronic Overdose

There is limited information regarding Chronic Overdose of Chlorothiazide (tablet) in the drug label.

Pharmacology

There is limited information regarding Chlorothiazide (tablet) Pharmacology in the drug label.

Mechanism of Action

Structure

File:Chlorothiazide (tablet)01.png

This image is provided by the National Library of Medicine.

Pharmacodynamics

There is limited information regarding Pharmacodynamics of Chlorothiazide (tablet) in the drug label.

Pharmacokinetics

There is limited information regarding Pharmacokinetics of Chlorothiazide (tablet) in the drug label.

Nonclinical Toxicology

There is limited information regarding Nonclinical Toxicology of Chlorothiazide (tablet) in the drug label.

Clinical Studies

There is limited information regarding Clinical Studies of Chlorothiazide (tablet) in the drug label.

How Supplied

Storage

There is limited information regarding Chlorothiazide (tablet) Storage in the drug label.

Images

Drug Images

{{#ask: Page Name::Chlorothiazide (tablet) |?Pill Name |?Drug Name |?Pill Ingred |?Pill Imprint |?Pill Dosage |?Pill Color |?Pill Shape |?Pill Size (mm) |?Pill Scoring |?NDC |?Drug Author |format=template |template=DrugPageImages |mainlabel=- |sort=Pill Name }}

Package and Label Display Panel

{{#ask: Label Page::Chlorothiazide (tablet) |?Label Name |format=template |template=DrugLabelImages |mainlabel=- |sort=Label Page }}

Patient Counseling Information

There is limited information regarding Patient Counseling Information of Chlorothiazide (tablet) in the drug label.

Precautions with Alcohol

Alcohol-Chlorothiazide (tablet) interaction has not been established. Talk to your doctor about the effects of taking alcohol with this medication.

Brand Names

CHLOROTHIAZIDE ®^[1]

Look-Alike Drug Names

A® — B®^[2]

Drug Shortage Status

Price

References

The contents of this FDA label are provided by the National Library of Medicine.

↑ "chlorothiazide tablet".
↑ "http://www.ismp.org". External link in |title= (help)

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[1] "chlorothiazide tablet".

[www.ismp.org-2] "http://www.ismp.org". External link in |title= (help)

[1]

[2]

@@ Line 12: / Line 12: @@
 <!--FDA-Labeled Indications and Dosage (Adult)-->
-|fdaLIADAdult======Condition1=====
+|fdaLIADAdult===Indications==
-* Dosing Information
+* Chlorothiazide is indicated as adjunctive therapy in [[edema]] associated with [[congestive heart failure]], [[cirrhosis|hepatic cirrhosis]], and corticosteroid and estrogen therapy.
-:* Dosage
+* Chlorothiazide has also been found useful in edema due to various forms of renal dysfunction such as [[nephrotic syndrome]], [[glomerulonephritis|acute glomerulonephritis]], and [[renal failure|chronic renal failure]].
-=====Condition2=====
+* Chlorothiazide is indicated in the management of [[hypertension]] either as the sole therapeutic agent or to enhance the effectiveness of other antihypertensive drugs in the more severe forms of [[hypertension]].
+|offLabelAdultGuideSupport=There is limited information regarding <i>Off-Label Guideline-Supported Use</i> of {{PAGENAME}} in adult patients.
-* Dosing Information
-:* Dosage
+|offLabelAdultNoGuideSupport=There is limited information regarding <i>Off-Label Non–Guideline-Supported Use</i> of {{PAGENAME}} in adult patients.
-=====Condition3=====
-* Dosing Information
+|fdaLIADPed=There is limited information regarding <i>FDA-Labeled Use</i> of {{PAGENAME}} in pediatric patients.
-:* Dosage
-=====Condition4=====
-* Dosing Information
+|offLabelPedGuideSupport=There is limited information regarding <i>Off-Label Guideline-Supported Use</i> of {{PAGENAME}} in pediatric patients.
-:* Dosage
-<!--Off-Label Use and Dosage (Adult)-->
+|offLabelPedNoGuideSupport=There is limited information regarding <i>Off-Label Non–Guideline-Supported Use</i> of {{PAGENAME}} in pediatric patients.
-<!--Guideline-Supported Use (Adult)-->
-|offLabelAdultGuideSupport======Condition1=====
-* Developed by:
-* Class of Recommendation:
-* Strength of Evidence:
-* Dosing Information
-:* Dosage
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-* Dosing Information
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-<!--Pediatric Indications and Dosage-->
-<!--FDA-Labeled Indications and Dosage (Pediatric)-->
-|fdaLIADPed======Condition1=====
-* Dosing Information
-:* Dosage
-=====Condition2=====
-There is limited information regarding <i>FDA-Labeled Use</i> of {{PAGENAME}} in pediatric patients.
-<!--Off-Label Use and Dosage (Pediatric)-->
-<!--Guideline-Supported Use (Pediatric)-->
-|offLabelPedGuideSupport======Condition1=====
-* Developed by:
-* Class of Recommendation:
-* Strength of Evidence:
-* Dosing Information
-:* Dosage
-=====Condition2=====
-There is limited information regarding <i>Off-Label Guideline-Supported Use</i> of {{PAGENAME}} in pediatric patients.
-<!--Non–Guideline-Supported Use (Pediatric)-->
-|offLabelPedNoGuideSupport======Condition1=====
-* Dosing Information
-:* Dosage
-=====Condition2=====
-There is limited information regarding <i>Off-Label Non–Guideline-Supported Use</i> of {{PAGENAME}} in pediatric patients.
-<!--Contraindications-->
 |contraindications=* Condition1
@@ Line 322: / Line 247: @@
 <!--Brand Names-->
 |brandNames=* CHLOROTHIAZIDE ®<ref>{{Cite web | title =chlorothiazide tablet | url =http://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=d652ef6f-2112-43ea-ba01-c3bf4f8d8030 }}</ref>
 |lookAlike=* A® — B®<ref name="www.ismp.org">{{Cite web  | last =  | first =  | title = http://www.ismp.org | url = http://www.ismp.org | publisher =  | date =  }}</ref>