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::* Preferred regimen: [[Vancomycin]] 30–45 mg/kg/day IV q8–12h {{and}} ([[Cefepime]] 2 g IV q8h {{or}} [[Ceftazidime]] 2 g IV q8h {{or}} [[Meropenem]] 2 g IV q8h)
::* Preferred regimen: [[Vancomycin]] 30–45 mg/kg/day IV q8–12h {{and}} ([[Cefepime]] 2 g IV q8h {{or}} [[Ceftazidime]] 2 g IV q8h {{or}} [[Meropenem]] 2 g IV q8h)


:* Pathogen-directed antimicrobial therapy
::* Enterococcus
:::* Preferred regimen: ([[Penicillin G]] 4 MU IV q4h {{or}} [[Ampicillin]] 2 g IV q4h) {{and}} [[Gentamicin]] 1–1.7 mg/kg IV q8h
::* Gram-negative bacilli
:::* Preferred regimen: [[Ceftriaxone]] 2 g IV q12h {{or}} [[Cefepime]] 2 g IV q12h {{or}} [[Meropenem]] 2 g IV q8h {{or}} [[Aztreonam]] 2 g IV q6h
::* Propionibacterium acnes
:::* Preferred regimen: ([[Penicillin G]] 4 MU IV q4h {{or}} [[Ampicillin]] 2 g IV q4h) {{withorwithout}} [[Gentamicin]] 1–1.7 mg/kg IV q8h
::* Staphylococcus, coagulase-negative
:::* Preferred regimen: [[Vancomycin]] 30–45 mg/kg/day IV q8–12h {{withorwithout}} [[Rifampin]] 600 mg IV/PO q24h
::* Staphylococcus aureus, methicillin-resistant
:::* Preferred regimen: ([[Nafcillin]] 2 g IV q4h {{or}} [[Oxacillin]] 2 g IV q4h) {{withorwithout}} [[Rifampin]] 600 mg IV/PO q24h
::* Staphylococcus aureus, methicillin-susceptible
:::* Preferred regimen: ([[Nafcillin]] 2 g IV q4h {{or}} [[Oxacillin]] 2 g IV q4h) {{withorwithout}} [[Rifampin]] 600 mg IV/PO q24h
::* Streptococcus agalactiae
:::* Preferred regimen: ([[Penicillin G]] 4 MU IV q4h {{or}} [[Ampicillin]] 2 g IV q4h) {{and}} [[Gentamicin]] 1–1.7 mg/kg IV q8h


==References==
==References==
{{reflist}}
{{reflist}}

Revision as of 08:09, 5 June 2015

Cerebrospinal fluid shunt infection

  • Cerebrospinal fluid shunt infection[1][2]
  • Empiric antimicrobial therapy
  • Pathogen-directed antimicrobial therapy
  • Enterococcus
  • Gram-negative bacilli


  • Propionibacterium acnes


  • Staphylococcus, coagulase-negative


  • Staphylococcus aureus, methicillin-resistant
  • Staphylococcus aureus, methicillin-susceptible


  • Streptococcus agalactiae

References

  1. Tunkel, Allan R.; Hartman, Barry J.; Kaplan, Sheldon L.; Kaufman, Bruce A.; Roos, Karen L.; Scheld, W. Michael; Whitley, Richard J. (2004-11-01). "Practice guidelines for the management of bacterial meningitis". Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America. 39 (9): 1267–1284. doi:10.1086/425368. ISSN 1537-6591. PMID 15494903.
  2. Bartlett, John (2012). Johns Hopkins ABX guide : diagnosis and treatment of infectious diseases. Burlington, MA: Jones and Bartlett Learning. ISBN 978-1449625580.