Lassa fever other diagnostic studies: Difference between revisions
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{{SK}} Lassa hemorrhagic fever; LHF | {{SK}} Lassa hemorrhagic fever; LHF | ||
==Overview== | ==Overview== | ||
Other laboratorys test to confirm the diagnosis of lassa fever includes [[Enzyme-linked immunosorbent serologic assays]] ([[ELISA]]), [[reverse transcription]]-[[polymerase chain reaction]] ([[RT-PCR]]) and [[Immunohistochemistry]] of skin, tissue and liver cells. | |||
==Other Diagnostic Studies== | ==Other Diagnostic Studies== | ||
Listed below are some of the diagnostic test used to confirm Lassa fever.<ref name=Prevention>{{cite web | title = The Centers for Disease Control and Prevention | url =http://www.cdc.gov/vhf/abroad/pdf/african-healthcare-setting-vhf.pdf }}</ref> | Listed below are some of the diagnostic test used to confirm Lassa fever.<ref name=Prevention>{{cite web | title = The Centers for Disease Control and Prevention | url =http://www.cdc.gov/vhf/abroad/pdf/african-healthcare-setting-vhf.pdf }}</ref> |
Revision as of 19:18, 8 June 2015
Lassa fever Microchapters |
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Lassa fever other diagnostic studies On the Web |
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Ammu Susheela, M.D. [2]
Synonyms and keywords: Lassa hemorrhagic fever; LHF
Overview
Other laboratorys test to confirm the diagnosis of lassa fever includes Enzyme-linked immunosorbent serologic assays (ELISA), reverse transcription-polymerase chain reaction (RT-PCR) and Immunohistochemistry of skin, tissue and liver cells.
Other Diagnostic Studies
Listed below are some of the diagnostic test used to confirm Lassa fever.[1]
Diagnostic Test | Samples required | Preparation & Storage | Detects |
ELISA (Serology) | Serum or plasma | Freeze or refrigerate | Detects Viral antigen, IgM and IgG antibody |
Polymerase Chain Reaction(PCR) | Serum or plasma or tissues (fresh frozen) | Freeze or refrigerate | Detects DNA, RNA (genetic material) from virus |
Immunohisto-chemistry | Liver biopsy from fatal cases | Fix in formalin and store or transport in room temperature | Detects viral antigen in cells |
Immunohisto-chemistry | Tissue biopsy from fatal cases | Fix in formalin and store or transport in room temperature | Detects viral antigen in cells |
Immunohisto-chemistry | Skin biopsy from fatal cases | Fix in formalin and store or transport in room temperature | Detects viral antigen in cells |
Data from the Center of Disease Control and Prevention