Lassa fever other diagnostic studies: Difference between revisions

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{{SK}} Lassa hemorrhagic fever; LHF
{{SK}} Lassa hemorrhagic fever; LHF
==Overview==
==Overview==
Other laboratorys test to confirm the diagnosis of lassa fever includes [[Enzyme-linked immunosorbent serologic assays]] ([[ELISA]]), [[reverse transcription]]-[[polymerase chain reaction]] ([[RT-PCR]]) and [[Immunohistochemistry]] of skin, tissue and liver cells.
==Other Diagnostic Studies==
==Other Diagnostic Studies==
Listed below are some of the diagnostic test used to confirm Lassa fever.<ref name=Prevention>{{cite web | title = The Centers for Disease Control and Prevention | url =http://www.cdc.gov/vhf/abroad/pdf/african-healthcare-setting-vhf.pdf }}</ref>
Listed below are some of the diagnostic test used to confirm Lassa fever.<ref name=Prevention>{{cite web | title = The Centers for Disease Control and Prevention | url =http://www.cdc.gov/vhf/abroad/pdf/african-healthcare-setting-vhf.pdf }}</ref>

Revision as of 19:18, 8 June 2015

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Ammu Susheela, M.D. [2]

Synonyms and keywords: Lassa hemorrhagic fever; LHF

Overview

Other laboratorys test to confirm the diagnosis of lassa fever includes Enzyme-linked immunosorbent serologic assays (ELISA), reverse transcription-polymerase chain reaction (RT-PCR) and Immunohistochemistry of skin, tissue and liver cells.

Other Diagnostic Studies

Listed below are some of the diagnostic test used to confirm Lassa fever.[1]

Diagnostic Test Samples required Preparation & Storage Detects
ELISA (Serology) Serum or plasma Freeze or refrigerate Detects Viral antigen, IgM and IgG antibody
Polymerase Chain Reaction(PCR) Serum or plasma or tissues (fresh frozen) Freeze or refrigerate Detects DNA, RNA (genetic material) from virus
Immunohisto-chemistry Liver biopsy from fatal cases Fix in formalin and store or transport in room temperature Detects viral antigen in cells
Immunohisto-chemistry Tissue biopsy from fatal cases Fix in formalin and store or transport in room temperature Detects viral antigen in cells
Immunohisto-chemistry Skin biopsy from fatal cases Fix in formalin and store or transport in room temperature Detects viral antigen in cells

Data from the Center of Disease Control and Prevention

References

  1. "The Centers for Disease Control and Prevention" (PDF).


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