Lassa fever history and symptoms: Difference between revisions
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Lassa fever after an [[incubation period]] of six to twenty-one days, manifest as an acute illness with multiorgan involvement and patients present with [[gastrointestinal]], neurological and [[pulmonary]] symptoms. | Lassa fever after an [[incubation period]] of six to twenty-one days, manifest as an acute illness with multiorgan involvement and patients present with [[gastrointestinal]], neurological and [[pulmonary]] symptoms. | ||
==History== | ==History and Symptoms== | ||
<br> | <br> | ||
| Line 58: | Line 35: | ||
==Less Common Symptoms== | ==Less Common Symptoms== | ||
The other symptoms arising from the affected organs are: | The other symptoms arising from the affected organs are: | ||
===Gastrointestinal tract=== | |||
*[[Hematemesis|Vomiting blood]] | |||
*[[Diarrhea]] (typically bloody) | |||
*[[Constipation]] | |||
*[[Dysphagia]] | |||
*[[Jaundice]] | |||
===Cardiovascular system=== | |||
* | *Facial or neck swelling | ||
*[[Hypotension]] or [[shock]] | |||
** [[Palpitations]] | |||
** [[Palpitations]] | * [[Respiratory tract]] | ||
* [[Respiratory tract]] | ** [[Difficulty breathing]] | ||
** [[Difficulty breathing]] | ** [[Sore throat]] | ||
** [[Sore throat]] | * [[Nervous system]] | ||
* [[Nervous system]] | |||
**[[Tremor]]. | **[[Tremor]]. | ||
** Unilateral or bilateral [[hearing loss]] | ** Unilateral or bilateral [[hearing loss]] | ||
** [[Seizure]]s. | ** [[Seizure]]s. | ||
===Diagnosis=== | |||
The current case definition for suspecting Lassa fever is as follows:<ref name=Prevention>{{cite web | title = The Centers for Disease Control and Prevention | url =http://www.cdc.gov/vhf/abroad/pdf/african-healthcare-setting-vhf.pdf }}</ref> | |||
{| style="border: 2px solid #DCDCDC; font-size: 90%; width: 60%;" align=left | |||
! style="padding: 0 5px; font-size: 100%; background: #4479BA" align=center| ''{{fontcolor|#FFF|Unexplained fever at least 38oC or 100.4oF for one week or more}}'' | |||
|- | |||
! style="padding: 0 5px; font-size: 95%; background: #DCDCDC" align=left | '''And 1 of the following:''' | |||
|- | |||
| rowspan="1" style="font-size: 95%; padding: 0 5px; background: #F5F5F5" | ▸ No response to standard treatment with the choice of regimen for most likely cause of [[fever]] ([[malaria]], [[typhoid fever]]). | |||
|- | |||
| rowspan="1" style="font-size: 95%; padding: 0 5px; background: #F5F5F5" | ▸ Readmitted within 3 weeks of inpatient care for an illness with [[fever]]. | |||
|- | |||
! style="padding: 0 5px; font-size: 95%; background: #DCDCDC" align=left | '''And 1 of the following''' | |||
|- | |||
| rowspan="1" style="font-size: 95%; padding: 0 5px; background: #F5F5F5" | ▸ [[Edema]] or [[bleeding]]. | |||
|- | |||
| rowspan="1" style="font-size: 95%; padding: 0 5px; background: #F5F5F5" | ▸ [[Sore throat]] and [[retrosternal pain]]/[[vomiting]]. | |||
|- | |||
| rowspan="1" style="font-size: 95%; padding: 0 5px; background: #F5F5F5" | ▸ Spontaneous [[abortion]] following [[fever]]. | |||
|- | |||
| rowspan="1" style="font-size: 95%; padding: 0 5px; background: #F5F5F5" | ▸ [[Hearing loss]] following [[fever]]. | |||
|} | |||
==References== | ==References== | ||
Revision as of 19:47, 9 June 2015
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Lassa fever Microchapters |
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Diagnosis |
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Treatment |
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Case Studies |
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Lassa fever history and symptoms On the Web |
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American Roentgen Ray Society Images of Lassa fever history and symptoms |
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Risk calculators and risk factors for Lassa fever history and symptoms |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [2]; Ammu Susheela, M.D. [3]
Synonyms and keywords: Lassa hemorrhagic fever; LHF
Overview
Lassa fever after an incubation period of six to twenty-one days, manifest as an acute illness with multiorgan involvement and patients present with gastrointestinal, neurological and pulmonary symptoms.
History and Symptoms
- The following graph demonstrates the common and rare symptoms associated with Lassa fever:
Common Symptoms
- Because the symptoms of Lassa fever are so varied and nonspecific, clinical diagnosis is often difficult.
- Non-specific symptoms include the following.
- Fever-Almost 100%
- Headache- 85%
- Muscle fatigue- 80%
- Retrosternal pain (pain behind the chest wall)-80%
- Weakness-77%.
- Dizziness-75%
- Sore throat-70%
- Back pain
- Cough-70%
- Vomiting-65%
- Abdominal pain-60%
- Diarrhea-40%
- Mucosal bleeding-40%
Less Common Symptoms
The other symptoms arising from the affected organs are:
Gastrointestinal tract
- Vomiting blood
- Diarrhea (typically bloody)
- Constipation
- Dysphagia
- Jaundice
Cardiovascular system
- Facial or neck swelling
- Hypotension or shock
- Respiratory tract
- Nervous system
- Tremor.
- Unilateral or bilateral hearing loss
- Seizures.
Diagnosis
The current case definition for suspecting Lassa fever is as follows:[1]
| Unexplained fever at least 38oC or 100.4oF for one week or more |
|---|
| And 1 of the following: |
| ▸ No response to standard treatment with the choice of regimen for most likely cause of fever (malaria, typhoid fever). |
| ▸ Readmitted within 3 weeks of inpatient care for an illness with fever. |
| And 1 of the following |
| ▸ Edema or bleeding. |
| ▸ Sore throat and retrosternal pain/vomiting. |
| ▸ Spontaneous abortion following fever. |
| ▸ Hearing loss following fever. |