Sandbox sc: Difference between revisions
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Shanshan Cen (talk | contribs) |
Shanshan Cen (talk | contribs) |
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| Line 14: | Line 14: | ||
::*2.1 '''First recurrence''' | ::*2.1 '''First recurrence''' | ||
:::* preferred regimen: | :::* preferred regimen: Same as first episode but stratified by severity | ||
::*2.2 '''Second recurrence''' | ::*2.2 '''Second recurrence''' | ||
:::* preferred regimen: | :::* preferred regimen: [[Vancomycin]] 125 mg 4 times daily for 14 days or 125 mg 2 times daily for 7 days or 125 mg once daily for 7 days or 125 mg once every 2 days for 8 days (4 doses) or 125 mg once every 3 days for 15 days (5 doses) | ||
==References== | ==References== | ||
{{reflist|2}} | {{reflist|2}} | ||
Revision as of 18:05, 1 July 2015
Clostridium difficile
- 1. Initial episode
- 1.1 Mild to moderate
- Preferred regimen: Metronidazole 500 mg orally q8h
- Alternative regimen(If no improvement in 5-7 days): Vancomycin 125 mg orally q6h
- 1.2 Severe
- Preferred regimen: Vancomycin 125 mg orally q6h
- 1.3 Severe complicated
- Preferred regimen: Vancomycin 500 mg orally q6h AND Metronidazole 500 mg IV q8h
- NOTE: If ileus present, add Vancomycin 500 mg in 100 mL normal saline per rectum q6h as retention enema
- 2.Recurrence
- 2.1 First recurrence
- preferred regimen: Same as first episode but stratified by severity
- 2.2 Second recurrence
- preferred regimen: Vancomycin 125 mg 4 times daily for 14 days or 125 mg 2 times daily for 7 days or 125 mg once daily for 7 days or 125 mg once every 2 days for 8 days (4 doses) or 125 mg once every 3 days for 15 days (5 doses)