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==Overview==
==Overview==
'''Legionellosis''' is an [[infectious disease]] caused by [[bacteria]] belonging to the [[genus]] ''[[Legionella]]''.<ref name=Sherris>{{cite book | author = Ryan KJ, Ray CG (editors) | title = Sherris Medical Microbiology | edition = 4th ed. | publisher = McGraw Hill | year = 2004 | isbn = 0838585299 }}</ref> Over 90% of legionellosis cases are caused by ''[[Legionella pneumophila]]'', a  ubiquitous aquatic organism that thrives in warm environments (25 to 45 °C with an optimum around 35 °C).
'''Legionellosis''' is an [[infectious disease]] caused by [[bacteria]] belonging to the [[genus]] ''[[Legionella]]''.<ref name=Sherris>{{cite book | author = Ryan KJ, Ray CG (editors) | title = Sherris Medical Microbiology | edition = 4th ed. | publisher = McGraw Hill | year = 2004 | isbn = 0838585299 }}</ref> Over 90% of legionellosis cases are caused by ''[[Legionella pneumophila]]'', a  ubiquitous aquatic organism that thrives in warm environments (25 to 45 °C with an optimum around 35 °C).
Legionellosis takes two distinct forms:''Legionnaires' disease'' is the more severe form of the infection and produces [[pneumonia]].<ref name=Baron>{{cite book | author =  Winn WC Jr  | chapter = Legionella | title = Baron's Medical Microbiology ''(Baron S ''et al'', eds.)| edition = 4th ed. | publisher = Univ of Texas Medical Branch | year = 1996 | url = http://www.ncbi.nlm.nih.gov/books/bv.fcgi?rid=mmed.section.2222 | isbn = 0-9631172-1-1 }}</ref> and  ''Pontiac fever'' is  caused by the same bacterium, but produces a milder [[upper respiratory infection|respiratory illness]] without pneumonia which resembles [[Acute (medicine)|acute]] [[influenza]].<ref name=Baron />


==Historical Perspective==
==Historical Perspective==

Revision as of 20:26, 30 July 2015

Legionellosis Microchapters

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Overview

Historical Perspective

Classification

Pathophysiology

Causes

Differentiating Legionellosis from other Diseases

Epidemiology and Demographics

Risk Factors

Natural History, Complications and Prognosis

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Legionellosis is an infectious disease caused by bacteria belonging to the genus Legionella.[1] Over 90% of legionellosis cases are caused by Legionella pneumophila, a ubiquitous aquatic organism that thrives in warm environments (25 to 45 °C with an optimum around 35 °C).

Historical Perspective

Classification

Legionellosis may be classified into three types based upon clinical presentations or affected organ systems: pulmonary infection (Legionnaires' disease), extrapulmonary infection, and Pontiac fever.

Pathophysiology

Causes

Differentiating Legionellosis from other Diseases

Epidemiology and Demographics

Risk Factors

Natural History, Complications and Prognosis

Diagnosis

History and Symptoms

Physical Examination

Laboratory Findings

Chest X ray

CT

Other Diagnostic Studies

Treatment

Medical Therapy

Primary Prevention

Secondary Prevention

Cost-Effectiveness of Therapy

Future or Investigational Therapies

Sources

  • CDC Legionellosis [2]


References

  1. Ryan KJ, Ray CG (editors) (2004). Sherris Medical Microbiology (4th ed. ed.). McGraw Hill. ISBN 0838585299.