Basal cell carcinoma natural history: Difference between revisions

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==Prognosis==
==Prognosis==
Although basal cell carcinoma rarely [[metastasis|metastasizes]], it grows locally with invasion and destruction of local tissues, without stopping. The cancer can impinge on vital structures and result in loss of extension or loss of function or rarely death. The vast majority of cases can be successfully treated before serious complications occur. The recurrence rate for the above treatment options ranges from 50% to 1% or less.
*Prognosis of basal cell carcinoma is usually excellent.
 
*Although basal cell carcinoma rarely [[metastasis|metastasizes]], it grows locally with invasion and destruction of local tissues, without stopping.
In choosing the therapy, one must weigh the benefit gained from the morbidity of the procedure.  As most basal cell carcinomas are slow growing, and not deadly; the health and age of the patient must be considered.  Although difficult to discuss, radiation therapy, topical [[chemotherapy]], or no treatment at all should be considered in ill or frail individuals in difficult to excise tumor of no immediate harm to the individual.  While methods with the highest cure rate should be considered for young and healthy individuals with long life expectancy. 
*The cancer can impinge on vital structures and result in loss of extension or loss of function or rarely death.
*The vast majority of cases can be successfully treated before serious complications occur.


==References==
==References==

Revision as of 02:17, 4 August 2015

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Saarah T. Alkhairy, M.D.

Overview

Basal cell carcinoma is slow-growing and locally invasive. Common complications of BCC include reoccurrence and development of other types of skin cancer.

Natural History

  • Patients with basal cell carcinoma are often asymptomatic.
  • Basal cell carcinoma is slow-growing and locally invasive.
  • The overall risk of metastases is estimated to be less than 0.1%.
  • The risk of invasion and recurrence is based on size, duration, location and subtype (sclerodermiform/morpheaform and micronodular clinical variants have a higher risk).
  • Even without a recurrence, a personal history of basal cell carcinoma increases the risk of developing all types of skin cancers.

Complications

Complications of basal cell carcinoma are the following:

Prognosis

  • Prognosis of basal cell carcinoma is usually excellent.
  • Although basal cell carcinoma rarely metastasizes, it grows locally with invasion and destruction of local tissues, without stopping.
  • The cancer can impinge on vital structures and result in loss of extension or loss of function or rarely death.
  • The vast majority of cases can be successfully treated before serious complications occur.

References

  1. 1.0 1.1 1.2 1.3 1.4 Evans, D G; Ladusans, E J; Rimmer, S; Burnell, L D; Thakker, N; Farndon, P A (1993). "Complications of the naevoid basal cell carcinoma syndrome: results of a population based study". Journal of Medical Genetics. 30 (6): 460–464. doi:10.1136/jmg.30.6.460. ISSN 1468-6244.


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