Sandbox suveen

Cholera

Disease	References	Editor	Status Antibiotics Antibiotic treatments for one to three days shorten the course of the disease and reduce the severity of the symptoms. People can recover even without them, if sufficient hydration and electrolyte balance is maintained. Doxycycline is typically used first line, although some strains of V. cholerae have shown resistance. Doxycycline single dose 300 mg or tetracycline 12,5 mg/kg 4 time/day for 3 days Other antibiotics proven to be effective include cotrimoxazole, erythromycin, tetracycline, chloramphenicol, and furazolidone. Fluoroquinolones, such as norfloxacin, also may be used, but resistance has been reported. Young children: erythromycin 12,5 mg/kg 4 time/day for 3 days for children below 6 months of age: 10 mg daily for 10 days add zinc for children 6 months to 5 years of age: 20mg daily for 10 days add zinc In many areas of the world, antibiotic resistance is increasing. Testing for resistance during an outbreak can help determine appropriate future choices. In Bangladesh, for example, most cases are resistant to tetracycline, trimethoprim-sulfamethoxazole, and erythromycin. Rapid diagnostic assay methods are available for the identification of multiple drug-resistant cases. New generation antimicrobials have been discovered which are effective against in in vitro studies. References