Acute promyelocytic leukemia history and symptoms

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Signs and symptoms of acute promyelocytic leukemia are similar to other forms of AML.

Symptoms

Symptoms include

• Fever
• Fatigue
• Weight loss or loss of appetite
• Shortness of breath with exertion
• Anemia
• Easy bruising or bleeding from thrombocytopenia and coagulopathy
• Petechiae (flat, pin-head sized spots under the skin caused by bleeding)
• Bone and joint pain
• Persistent or frequent infections (from lack of normal white blood cells)