Zollinger-Ellison syndrome history and symptoms: Difference between revisions
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==History and Symptoms== | ==History and Symptoms== | ||
Patients with Zollinger–Ellison syndrome may experience [[abdominal pain]] and [[diarrhea]]. The diagnosis is also suspected in patients without symptoms who have severe [[ulceration]] of the stomach and small bowel, especially if they fail to respond to treatment. | |||
Patients with Zollinger–Ellison syndrome may experience abdominal pain and [[diarrhea]]. The diagnosis is also suspected in patients without symptoms who have severe ulceration of the stomach and small bowel, especially if they fail to respond to treatment. | * Chronic [[diarrhea]], including [[steatorrhea]] (fatty stools) | ||
* Chronic diarrhea, including [[steatorrhea]] (fatty stools) | |||
* Pain in the esophagus, especially between and after meals at night | * Pain in the esophagus, especially between and after meals at night | ||
* Nausea | * [[Nausea]] | ||
* Wheezing | * [[Wheezing]] | ||
* Vomiting blood (digested blood) | * Vomiting blood (digested blood) | ||
* Malnourishment | * [[Malnourishment]] | ||
* Loss of weight due to loss of appetite | * Loss of weight due to loss of appetite | ||
[[Gastrinoma]]s may occur as single tumors or as multiple, small tumors. About one-half to two-thirds of single gastrinomas are [[malignant]] tumors that most commonly spread to the [[liver]] and [[lymph node]] | [[Gastrinoma]]s may occur as single tumors or as multiple, small tumors. About one-half to two-thirds of single gastrinomas are [[malignant]] tumors that most commonly spread to the [[liver]] and [[lymph node]] near the pancreas and small bowel. Nearly 25 percent of patients with gastrinomas have multiple tumors as part of a condition called [[multiple endocrine neoplasia]] type I (MEN I). MEN I patients have tumors in their [[pituitary gland]] and [[parathyroid gland]]s, in addition to tumors of the pancreas. | ||
==References== | ==References== | ||
Revision as of 13:35, 14 August 2015
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
History and Symptoms
Patients with Zollinger–Ellison syndrome may experience abdominal pain and diarrhea. The diagnosis is also suspected in patients without symptoms who have severe ulceration of the stomach and small bowel, especially if they fail to respond to treatment.
- Chronic diarrhea, including steatorrhea (fatty stools)
- Pain in the esophagus, especially between and after meals at night
- Nausea
- Wheezing
- Vomiting blood (digested blood)
- Malnourishment
- Loss of weight due to loss of appetite
Gastrinomas may occur as single tumors or as multiple, small tumors. About one-half to two-thirds of single gastrinomas are malignant tumors that most commonly spread to the liver and lymph node near the pancreas and small bowel. Nearly 25 percent of patients with gastrinomas have multiple tumors as part of a condition called multiple endocrine neoplasia type I (MEN I). MEN I patients have tumors in their pituitary gland and parathyroid glands, in addition to tumors of the pancreas.