Oncogenesis: Difference between revisions
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==Overview== | ==Overview== | ||
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===See also=== | ===See also=== | ||
* [[carcinogen]] a substance, radionuclide or radiation directly involved in the promotion of cancer. | *[[carcinogen]] a substance, radionuclide or radiation directly involved in the promotion of cancer. | ||
* [[mutagen]] a physical or chemical agent that changes the genetic information of an organism. | *[[mutagen]] a physical or chemical agent that changes the genetic information of an organism. | ||
* [[teratogen]] | *[[teratogen]] | ||
* [[oncogene]] a modified gene believed to cause cancer. | *[[oncogene]] a modified gene believed to cause cancer. | ||
==References== | ==References== | ||
{{reflist|2}} | |||
Hornberg, J., Binder, B., Bruggeman, F., Schoeber, B., Heinrich, R., Westerhoff, H., "Control of MAPK signalling: from complexity to what really matters", Oncogene, Vol. 24, pp 5533-5542, (published online 20June2005). | Hornberg, J., Binder, B., Bruggeman, F., Schoeber, B., Heinrich, R., Westerhoff, H., "Control of MAPK signalling: from complexity to what really matters", Oncogene, Vol. 24, pp 5533-5542, (published online 20June2005). | ||
Revision as of 15:25, 14 August 2015
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Overview
Oncogenesis is the process of malignant transformation leading to the formation of a tumor (tumorigenesis). It is characterized by a progression of changes on cellular and genetic level that ultimately reprogram a cell to undergo uncontrolled cell division, thus forming a malignant mass.
Oncovirinae, retroviruses which contain an onc gene, are categorized as oncogenic because they trigger the growth of tumorous tissues in the host. This process is also referred to as viral transformation.
See also
- carcinogen a substance, radionuclide or radiation directly involved in the promotion of cancer.
- mutagen a physical or chemical agent that changes the genetic information of an organism.
- teratogen
- oncogene a modified gene believed to cause cancer.
References
Hornberg, J., Binder, B., Bruggeman, F., Schoeber, B., Heinrich, R., Westerhoff, H., "Control of MAPK signalling: from complexity to what really matters", Oncogene, Vol. 24, pp 5533-5542, (published online 20June2005). Template:WH Template:WikiDoc Sources