Pheochromocytoma pathophysiology: Difference between revisions
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{{Pheochromocytoma}} | {{Pheochromocytoma}} | ||
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==Overview== | ==Overview== | ||
==Pathophysiology== | ==Pathophysiology== |
Revision as of 17:36, 17 August 2015
Pheochromocytoma Microchapters |
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Pheochromocytoma pathophysiology On the Web |
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Risk calculators and risk factors for Pheochromocytoma pathophysiology |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Pathophysiology
Traditionally it is known as the "10% tumor":
- bilateral disease is present in approximately 10% of patients
- approximately 10% of tumours are malignant
- approximately 10% are located in chromaffin tissue outside of the adrenal gland
- Approximately 10% arise in childhood
- Approximately 10% are familial
- Approximately 10% recur after being resected
- Approximately 10% patients do not have hypertension (Campbell's Urology)
Tumor Location
In adults, 90% tumors are located unilaterally and are solitary, and 10% are located outside the adrenal gland. In children 50% are adrenal, while 25% are bilateral and 25% are extraadrenal. The common extradrenal locations are the abdomen, thorax and urinary bladder.
Images
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Micrograph of pheochromocytoma.
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Histopathology of adrenal pheochromocytoma. Adrenectomy specimen.
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Micrograph of pheochromocytoma.
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Micrograph of pheochromocytoma.
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Bilateral pheochromocytoma in MEN2. Gross image.