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==Overview==
==Overview==
==Risk Factors==
==Risk Factors==
* The most potent risk factor in the development of MMC is [[Immune suppression]].
* The most potent risk factor in the development of Merkel cell cancer is [[Immune suppression]].


* According to a recent study in the Lancet, Merkel cell carcinoma occurs 13.4 times more often in people with advanced [[HIV]] as compared to the general population. Solid organ transplant recipients have  similarly increased risk.
* According to a recent study in the Lancet, Merkel cell carcinoma occurs 13.4 times more often in people with advanced [[HIV]] as compared to the general population. Solid organ transplant recipients have  similarly increased risk.

Revision as of 14:44, 20 August 2015

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Risk Factors

  • The most potent risk factor in the development of Merkel cell cancer is Immune suppression.
  • According to a recent study in the Lancet, Merkel cell carcinoma occurs 13.4 times more often in people with advanced HIV as compared to the general population. Solid organ transplant recipients have similarly increased risk.
  • people treated heavily with methoxsalen (psoralen) and ultraviolet A (PUVA) for psoriasis are at increased risk for MCC. [1]

References

  1. National Cancer Institute. Physician Data Query Database 2015. http://www.cancer.gov/publications/pdp


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