Brain tumor pathophysiology

Brain tumor Microchapters
Patient Information
Overview
Classification Adult brain tumors Glioblastoma multiforme Oligodendroglioma Meningioma Hemangioblastoma Pituitary adenoma Schwannoma Primary CNS lymphoma Childhood brain tumors Pilocytic astrocytoma Medulloblastoma Ependymoma Craniopharyngioma Pinealoma Metastasis Lung cancer Breast cancer Melanoma Gastrointestinal tract cancer Renal cell carcinoma Osteoblastoma Head and neck cancer Neuroblastoma Lymphoma Prostate cancer
Causes
Differentiating Brain Tumor from other Diseases

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Pathophysiology

Immunohistochemical profile of the more common brain tumors.

• Astrocytoma - GFAP (Glial Fibrillary Acidic Protein) less positively in poorly differentiated tumors.
• Oligodendroglioma - Fried eggs GFAP-negative. Minigemistocytes GFAP-positive.
• Ependymoma - GFAP, S100, variable EMA-dot positivity.
• Medulloblastoma - Synaptophysin, Neu N, focal GFAP
• Meningioma - EMA, Vimentin.

References

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