Pancreatic cancer pathophysiology: Difference between revisions
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==Pathophysiology== | ==Pathophysiology== | ||
===Pathology=== | |||
The most common form of pancreatic cancer (adenocarcinoma) is typically characterized by moderately to [[Anaplasia|poorly differentiated]] glandular structures on microscopic examination. There is typically considerable [[desmoplasia]] or formation of a dense fibrous [[Stroma (animal tissue)|stroma]] or structural tissue consisting of a range of [[cell type]]s (including [[myofibroblast]]s, [[macrophage]]s, [[lymphocyte]]s and [[mast cell]]s) and deposited material (such as [[type I collagen]] and [[hyaluronic acid]]). | The most common form of pancreatic cancer (adenocarcinoma) is typically characterized by moderately to [[Anaplasia|poorly differentiated]] glandular structures on microscopic examination. There is typically considerable [[desmoplasia]] or formation of a dense fibrous [[Stroma (animal tissue)|stroma]] or structural tissue consisting of a range of [[cell type]]s (including [[myofibroblast]]s, [[macrophage]]s, [[lymphocyte]]s and [[mast cell]]s) and deposited material (such as [[type I collagen]] and [[hyaluronic acid]]). | ||
Revision as of 19:25, 21 August 2015
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Parminder Dhingra, M.D. [2]
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Overview
The pathophysiology of pancreatic adenocarcinoma includes considerable desmoplasia or formation of a dense fibrous stroma or structural tissue consisting of a range of cell types (including myofibroblasts, macrophages, lymphocytes and mast cells) and deposited material (such as type I collagen and hyaluronic acid).
Pathophysiology
Pathology
The most common form of pancreatic cancer (adenocarcinoma) is typically characterized by moderately to poorly differentiated glandular structures on microscopic examination. There is typically considerable desmoplasia or formation of a dense fibrous stroma or structural tissue consisting of a range of cell types (including myofibroblasts, macrophages, lymphocytes and mast cells) and deposited material (such as type I collagen and hyaluronic acid).