Melanoma staging: Difference between revisions
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==Staging== | ==Staging== | ||
'' | ===2010 American Joint Committee on Cancer (AJC) TNM Definitions for Melanoma== | ||
===Primary Tumor (T)=== | |||
{| {{table}} | |||
| align="center" style="background:#f0f0f0;"|'''T Classification''' | |||
| align="center" style="background:#f0f0f0;"|'''Thickness''' | |||
| align="center" style="background:#f0f0f0;"|'''Ulceration status/mitoses''' | |||
|- | |||
| T1a||≤ 1.0 mm||No ulceration & <1 mitosis/mm2 | |||
|- | |||
| T1b||≤ 1.0 mm||Ulcerated or ≥1 mitosis/mm2 | |||
|- | |||
| T2a||1.01 - 2.0 mm||No ulceration | |||
|- | |||
| T2b||1.01 - 2.0 mm||Ulcerated | |||
|- | |||
| T3a||2.01 - 4.0 mm||No ulceration | |||
|- | |||
| T3b||2.01 - 4.0 mm||Ulcerated | |||
|- | |||
| T4a||> 4.0 mm||No ulceration | |||
|- | |||
| T4b||> 4.0 mm||Ulcerated | |||
|- | |||
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|} | |||
Also of importance are the "Clark level" and "Breslow depth" which refer to the microscopic depth of tumor invasion.<ref> [http://chorus.rad.mcw.edu/doc/00955.html Malignant melanoma: staging] at Collaborative Hypertext of Radiology</ref> | Also of importance are the "Clark level" and "Breslow depth" which refer to the microscopic depth of tumor invasion.<ref> [http://chorus.rad.mcw.edu/doc/00955.html Malignant melanoma: staging] at Collaborative Hypertext of Radiology</ref> | ||
Melanoma | ===Staging of Melanoma=== | ||
'''Stage 0''': Melanoma in Situ (Clark Level I), 100% Survival | '''Stage 0''': Melanoma in Situ (Clark Level I), 100% Survival | ||
Revision as of 20:46, 21 August 2015
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
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Melanoma Microchapters |
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Diagnosis |
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Treatment |
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Case Studies |
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Melanoma staging On the Web |
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American Roentgen Ray Society Images of Melanoma staging |
Overview
Staging
=2010 American Joint Committee on Cancer (AJC) TNM Definitions for Melanoma
Primary Tumor (T)
| T Classification | Thickness | Ulceration status/mitoses |
| T1a | ≤ 1.0 mm | No ulceration & <1 mitosis/mm2 |
| T1b | ≤ 1.0 mm | Ulcerated or ≥1 mitosis/mm2 |
| T2a | 1.01 - 2.0 mm | No ulceration |
| T2b | 1.01 - 2.0 mm | Ulcerated |
| T3a | 2.01 - 4.0 mm | No ulceration |
| T3b | 2.01 - 4.0 mm | Ulcerated |
| T4a | > 4.0 mm | No ulceration |
| T4b | > 4.0 mm | Ulcerated |
Also of importance are the "Clark level" and "Breslow depth" which refer to the microscopic depth of tumor invasion.[1]
Staging of Melanoma
Stage 0: Melanoma in Situ (Clark Level I), 100% Survival
Stage I/II: Invasive Melanoma, 85-95% Survival
- T1a: Less than 1.00 mm primary, w/o Ulceration, Clark Level II-III
- T1b: Less than 1.00 mm primary, w/Ulceration or Clark Level IV-V
- T2a: 1.00-2.00 mm primary, w/o Ulceration
Stage II: High Risk Melanoma, 40-85% Survival
- T2b: 1.00-2.00 mm primary, w/ Ulceration
- T3a: 2.00-4.00 mm primary, w/o Ulceration
- T3b: 2.00-4.00 mm primary, w/ Ulceration
- T4a: 4.00 mm or greater primary w/o Ulceration
- T4b: 4.00 mm or greater primary w/ Ulceration
Stage III: Regional Metastasis, 25-60% Survival
- N1: Single Positive Lymph Node
- N2: 2-3 Positive Lymph Nodes OR Regional Skin/In-Transit Metastasis
- N3: 4 Positive Lymph Nodes OR Lymph Node and Regional Skin/In Transit Metastases
Stage IV: Distant Metastasis, 9-15% Survival
- M1a: Distant Skin Metastasis, Normal LDH
- M1b: Lung Metastasis, Normal LDH
- M1c: Other Distant Metastasis OR Any Distant Metastasis with Elevated LDH
Based Upon AJCC 5-Year Survival With Proper Treatment
References
- ↑ Malignant melanoma: staging at Collaborative Hypertext of Radiology