Adrenocortical carcinoma natural history: Difference between revisions
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==Prognosis== | ==Prognosis== | ||
Adrenocortical carcinoma, generally, carries a poor prognosis<ref name=allolio>{{cite journal | author = Allolio B, Fassnacht M | title = Clinical review: Adrenocortical carcinoma: clinical update. | journal = J Clin Endocrinol Metab | volume = 91 | issue = 6 | pages = 2027-37 | year = 2006 | id = PMID 16551738}} [http://jcem.endojournals.org/cgi/content/full/91/6/2027 Free Full Text].</ref> | Adrenocortical carcinoma, generally, carries a poor prognosis.<ref name=allolio>{{cite journal | author = Allolio B, Fassnacht M | title = Clinical review: Adrenocortical carcinoma: clinical update. | journal = J Clin Endocrinol Metab | volume = 91 | issue = 6 | pages = 2027-37 | year = 2006 | id = PMID 16551738}} [http://jcem.endojournals.org/cgi/content/full/91/6/2027 Free Full Text].</ref> | ||
Five-year disease-free survival for a complete resection of a [[Cancer staging|stage]] I-III is approximately 30%.<ref name=allolio/> | |||
The most important '''prognostic factors''' are: | The most important '''prognostic factors''' are: | ||
* Age of the patient. | * Age of the patient. | ||
* Stage of the tumor. | * Stage of the tumor. | ||
Poor prognostic factors: | Poor prognostic factors include: | ||
* Mitotic activity. | * Mitotic activity. | ||
* Venous invasion. | * Venous invasion. | ||
Revision as of 13:38, 26 August 2015
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Adrenocortical carcinoma Microchapters |
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Differentiating Adrenocortical carcinoma from other Diseases |
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Diagnosis |
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Treatment |
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Case Study |
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Adrenocortical carcinoma natural history On the Web |
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American Roentgen Ray Society Images of Adrenocortical carcinoma natural history |
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Risk calculators and risk factors for Adrenocortical carcinoma natural history |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Raviteja Guddeti, M.B.B.S. [2] Ahmad Al Maradni, M.D. [3]
Complications
The following are the complications of Adrenocortical carcinoma:
- Cushing's syndrome
- Conn syndrome
- Hypertension
- Virilization
- Feminization
- Local metastasis and tumor thrombus formation
- Paraneoplastic syndrome
- Distant metastasis
Prognosis
Adrenocortical carcinoma, generally, carries a poor prognosis.[1] Five-year disease-free survival for a complete resection of a stage I-III is approximately 30%.[1] The most important prognostic factors are:
- Age of the patient.
- Stage of the tumor.
Poor prognostic factors include:
- Mitotic activity.
- Venous invasion.
- Weight more than 50 Kg.
- Diameter more than 6.5 cm.
- Ki-67/MIB1 labeling index.
References
- ↑ 1.0 1.1 Allolio B, Fassnacht M (2006). "Clinical review: Adrenocortical carcinoma: clinical update". J Clin Endocrinol Metab. 91 (6): 2027–37. PMID 16551738. Free Full Text.