Oncocytoma pathophysiology: Difference between revisions
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==Pathophysiology== | ==Pathophysiology== | ||
This is an [[epithelial]] tumor composed of large, [[eosinophil]]ic cells having small, round, benign-appearing [[Cell nucleus|nuclei]] that have large [[nucleoli]]. It is thought to arise from the intercalated cells of [[collecting duct]]s. It is not an uncommon tumor, accounting for approximately 5% to 15% of surgically resected [[renal]] [[neoplasm]]s. Ultrastructurally, the eosinophilic cells have numerous [[mitochondria]]. In gross appearance, the tumors are tan or mahogany brown, relatively homogeneous, and usually well encapsulated. However, they may achieve a large size (up to 12 cm in diameter). Although anecdotal cases with metastases have been reported, the tumor is considered [[benign]]. There are some familial cases in which these tumors are multicentric rather than solitary. <ref>Robbins pathology, page 1015</ref> | This is an [[epithelial]] tumor composed of large, [[eosinophil]]ic cells having small, round, benign-appearing [[Cell nucleus|nuclei]] that have large [[nucleoli]]. It is thought to arise from the intercalated cells of [[collecting duct]]s. It is not an uncommon tumor, accounting for approximately 5% to 15% of surgically resected [[renal]] [[neoplasm]]s. Ultrastructurally, the eosinophilic cells have numerous [[mitochondria]]. In gross appearance, the tumors are tan or mahogany brown, relatively homogeneous, and usually well encapsulated. However, they may achieve a large size (up to 12 cm in diameter). Although anecdotal cases with metastases have been reported, the tumor is considered [[benign]]. There are some familial cases in which these tumors are multicentric rather than solitary. <ref>Robbins pathology, page 1015</ref> | ||
==References== | ==References== | ||
{{Reflist|2}} | {{Reflist|2}} | ||
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[[Category:Types of cancer]] | [[Category:Types of cancer]] | ||
[[Category:Urology]] | [[Category:Urology]] | ||
[[Category:Disease]] | [[Category:Disease]] | ||
[[Category:Mature chapter]] | [[Category:Mature chapter]] | ||
Revision as of 20:21, 26 August 2015
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
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Overview
Pathophysiology
This is an epithelial tumor composed of large, eosinophilic cells having small, round, benign-appearing nuclei that have large nucleoli. It is thought to arise from the intercalated cells of collecting ducts. It is not an uncommon tumor, accounting for approximately 5% to 15% of surgically resected renal neoplasms. Ultrastructurally, the eosinophilic cells have numerous mitochondria. In gross appearance, the tumors are tan or mahogany brown, relatively homogeneous, and usually well encapsulated. However, they may achieve a large size (up to 12 cm in diameter). Although anecdotal cases with metastases have been reported, the tumor is considered benign. There are some familial cases in which these tumors are multicentric rather than solitary. [1]
References
- ↑ Robbins pathology, page 1015