Pheochromocytoma medical therapy

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Medical Therapy

Any surgical option requires prior treatment with both the non-specific alpha adrenoceptor blocker phenoxybenzamine to counteract hypertension and the beta-1 adrenoceptor antagonist atenolol to reduce cardiac output. Given before surgery, these can also block the effect of a sudden release of adrenaline during tumour removal, which would otherwise endanger the anaethetised patient.

Contraindicated medications

Pheochromocytoma is considered an absolute contraindication to the use of the following medications:

• Atomoxetine
• Glucagon
• Minoxidil
• Metoclopramide